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Items: 1 to 20 of 144

2.

Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways.

Kannaiyan R, Manu KA, Chen L, Li F, Rajendran P, Subramaniam A, Lam P, Kumar AP, Sethi G.

Apoptosis. 2011 Oct;16(10):1028-41. doi: 10.1007/s10495-011-0629-6.

PMID:
21786165
4.

Guggulsterone for Chemoprevention of Cancer.

Shishodia S, Azu N, Rosenzweig JA, Jackson DA.

Curr Pharm Des. 2016;22(3):294-306. Review.

PMID:
26561056
5.
6.

z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo.

Xiao D, Singh SV.

Mol Cancer Ther. 2008 Jan;7(1):171-80. doi: 10.1158/1535-7163.MCT-07-0491.

7.

Reactive oxygen species-dependent apoptosis by gugulipid extract of Ayurvedic medicine plant Commiphora mukul in human prostate cancer cells is regulated by c-Jun N-terminal kinase.

Xiao D, Zeng Y, Prakash L, Badmaev V, Majeed M, Singh SV.

Mol Pharmacol. 2011 Mar;79(3):499-507. doi: 10.1124/mol.110.068551. Epub 2010 Nov 29.

9.

Epicatechin gallate induces cell death via p53 activation and stimulation of p38 and JNK in human colon cancer SW480 cells.

Cordero-Herrera I, Martín MA, Bravo L, Goya L, Ramos S.

Nutr Cancer. 2013;65(5):718-28. doi: 10.1080/01635581.2013.795981.

PMID:
23859040
10.

3,3'-Diindolylmethane exhibits antileukemic activity in vitro and in vivo through a Akt-dependent process.

Gao N, Cheng S, Budhraja A, Liu EH, Chen J, Chen D, Yang Z, Luo J, Shi X, Zhang Z.

PLoS One. 2012;7(2):e31783. doi: 10.1371/journal.pone.0031783. Epub 2012 Feb 21.

12.

14-3-3 zeta is a molecular target in guggulsterone induced apoptosis in head and neck cancer cells.

Macha MA, Matta A, Chauhan S, Siu KM, Ralhan R.

BMC Cancer. 2010 Nov 30;10:655. doi: 10.1186/1471-2407-10-655.

13.

MK-2206 induces cell cycle arrest and apoptosis in HepG2 cells and sensitizes TRAIL-mediated cell death.

Jiao P, Zhou YS, Yang JX, Zhao YL, Liu QQ, Yuan C, Wang FZ.

Mol Cell Biochem. 2013 Oct;382(1-2):217-24.

PMID:
23797319
14.

Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts.

An MJ, Cheon JH, Kim SW, Kim ES, Kim TI, Kim WH.

Cancer Lett. 2009 Jun 28;279(1):93-100. doi: 10.1016/j.canlet.2009.01.026. Epub 2009 Feb 18.

PMID:
19232820
15.

Guggulsterone attenuates activation and survival of hepatic stellate cell by inhibiting nuclear factor kappa B activation and inducing apoptosis.

Kim BH, Yoon JH, Yang JI, Myung SJ, Lee JH, Jung EU, Yu SJ, Kim YJ, Lee HS, Kim CY.

J Gastroenterol Hepatol. 2013 Dec;28(12):1859-68. doi: 10.1111/jgh.12314.

PMID:
23808824
16.

Elesclomol, counteracted by Akt survival signaling, enhances the apoptotic effect of chemotherapy drugs in breast cancer cells.

Qu Y, Wang J, Sim MS, Liu B, Giuliano A, Barsoum J, Cui X.

Breast Cancer Res Treat. 2010 Jun;121(2):311-21. doi: 10.1007/s10549-009-0470-6. Epub 2009 Jul 16.

PMID:
19609669
17.

Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways.

Gao N, Budhraja A, Cheng S, Liu EH, Chen J, Yang Z, Chen D, Zhang Z, Shi X.

Cell Death Dis. 2011 Apr 7;2:e140. doi: 10.1038/cddis.2011.22.

18.

Selenocystine induces S-phase arrest and apoptosis in human breast adenocarcinoma MCF-7 cells by modulating ERK and Akt phosphorylation.

Chen T, Wong YS.

J Agric Food Chem. 2008 Nov 26;56(22):10574-81. doi: 10.1021/jf802125t.

PMID:
18959417
19.

Naphtho[1,2-b]furan-4,5-dione induces apoptosis and S-phase arrest of MDA-MB-231 cells through JNK and ERK signaling activation.

Lin KL, Su JC, Chien CM, Tseng CH, Chen YL, Chang LS, Lin SR.

Toxicol In Vitro. 2010 Feb;24(1):61-70. doi: 10.1016/j.tiv.2009.09.002. Epub 2009 Sep 9.

PMID:
19747539
20.

Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.

Eur J Pharmacol. 2007 Jun 1;563(1-3):49-60. Epub 2007 Feb 8.

PMID:
17341418

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