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SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.

Strande JL, Hsu A, Su J, Fu X, Gross GJ, Baker JE.

Basic Res Cardiol. 2007 Jul;102(4):350-8. Epub 2007 Apr 30.


Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury.

Strande JL, Widlansky ME, Tsopanoglou NE, Su J, Wang J, Hsu A, Routhu KV, Baker JE.

Cardiovasc Res. 2009 Jul 15;83(2):325-34. doi: 10.1093/cvr/cvp122. Epub 2009 Apr 20.


Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways.

Hu Y, Chen X, Pan TT, Neo KL, Lee SW, Khin ES, Moore PK, Bian JS.

Pflugers Arch. 2008 Jan;455(4):607-16. Epub 2007 Aug 1.


Rho kinase activation plays a major role as a mediator of irreversible injury in reperfused myocardium.

Hamid SA, Bower HS, Baxter GF.

Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2598-606. Epub 2007 Jan 12.


KR-31762, a novel KATP channel opener, exerts cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury.

Lee SH, Yang MK, Lim JH, Seo HW, Yi KY, Yoo SE, Lee BH, Won HS, Lee CS, Choi WS, Shin HS.

Arch Pharm Res. 2008 Apr;31(4):482-9. doi: 10.1007/s12272-001-1182-9. Epub 2008 May 1.


GSK3beta inhibition and K(ATP) channel opening mediate acute opioid-induced cardioprotection at reperfusion.

Gross ER, Hsu AK, Gross GJ.

Basic Res Cardiol. 2007 Jul;102(4):341-9. Epub 2007 Apr 23.


Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling.

Strande JL, Hsu A, Su J, Fu X, Gross GJ, Baker JE.

J Pharmacol Exp Ther. 2008 Mar;324(3):1045-54. Epub 2007 Nov 30.


NDRG2: a newly identified mediator of insulin cardioprotection against myocardial ischemia-reperfusion injury.

Sun Z, Tong G, Ma N, Li J, Li X, Li S, Zhou J, Xiong L, Cao F, Yao L, Wang H, Shen L.

Basic Res Cardiol. 2013 May;108(3):341. doi: 10.1007/s00395-013-0341-5. Epub 2013 Mar 6.


Inhibition of Mas G-protein signaling improves coronary blood flow, reduces myocardial infarct size, and provides long-term cardioprotection.

Zhang T, Li Z, Dang H, Chen R, Liaw C, Tran TA, Boatman PD, Connolly DT, Adams JW.

Am J Physiol Heart Circ Physiol. 2012 Jan 1;302(1):H299-311. doi: 10.1152/ajpheart.00723.2011. Epub 2011 Oct 14.


Effect of pressure overload on cardioprotection of mitochondrial KATP channels and GSK-3beta: interaction with the MPT pore.

Mozaffari MS, Schaffer SW.

Am J Hypertens. 2008 May;21(5):570-5. doi: 10.1038/ajh.2008.25. Epub 2008 Mar 20.


Protease-activated receptor 2-mediated protection of myocardial ischemia-reperfusion injury: role of transient receptor potential vanilloid receptors.

Zhong B, Wang DH.

Am J Physiol Regul Integr Comp Physiol. 2009 Dec;297(6):R1681-90. doi: 10.1152/ajpregu.90746.2008. Epub 2009 Oct 7.


Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats.

Deschamps AM, Murphy E.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1806-13. doi: 10.1152/ajpheart.00283.2009. Epub 2009 Aug 28.


Preconditioning by isoflurane retains its protection against ischemia-reperfusion injury in postinfarct remodeled rat hearts.

Lucchinetti E, Jamnicki M, Fischer G, Zaugg M.

Anesth Analg. 2008 Jan;106(1):17-23, table of contents. doi: 10.1213/01.ane.0000289527.70545.ed.


Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.

Yasuda S, Kobayashi H, Iwasa M, Kawamura I, Sumi S, Narentuoya B, Yamaki T, Ushikoshi H, Nishigaki K, Nagashima K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1558-65. doi: 10.1152/ajpheart.00712.2008. Epub 2009 Mar 13.


PPAR-alpha activation protects the type 2 diabetic myocardium against ischemia-reperfusion injury: involvement of the PI3-Kinase/Akt and NO pathway.

Bulhak AA, Jung C, Ostenson CG, Lundberg JO, Sjöquist PO, Pernow J.

Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H719-27. doi: 10.1152/ajpheart.00394.2008. Epub 2009 Jan 16.


Catalpol decreases peroxynitrite formation and consequently exerts cardioprotective effects against ischemia/reperfusion insult.

Huang C, Cui Y, Ji L, Zhang W, Li R, Ma L, Xing W, Zhou H, Chen B, Yu J, Zhang H.

Pharm Biol. 2013 Apr;51(4):463-73. doi: 10.3109/13880209.2012.740052. Epub 2013 Jan 22.


Myocardial reperfusion injury management: erythropoietin compared with postconditioning.

Tamareille S, Ghaboura N, Treguer F, Khachman D, Croué A, Henrion D, Furber A, Prunier F.

Am J Physiol Heart Circ Physiol. 2009 Dec;297(6):H2035-43. doi: 10.1152/ajpheart.00472.2009. Epub 2009 Jul 17. Erratum in: Am J Physiol Heart Circ Physiol. 2009 Dec;297:H2035.


Local delivery of a PKCε-activating peptide limits ischemia reperfusion injury in the aged female rat heart.

Lancaster TS, Jefferson SJ, Korzick DH.

Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1242-9. doi: 10.1152/ajpregu.00851.2010. Epub 2011 Aug 31.


Treatment of rats with hypolipidemic compound pirinixic acid protects their hearts against ischemic injury: are mitochondrial K(ATP) channels and reactive oxygen species involved?

Nemčeková M, Čarnická S, Ferko M, Muráriková M, Ledvényiová V, Ravingerová T.

Physiol Res. 2013;62(5):577-84. Epub 2013 Sep 10.

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