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Items: 1 to 20 of 91

1.

S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury.

Dey A, Caro AA, Cederbaum AI.

Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G91-103. Epub 2007 Apr 19.

2.
3.

Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice.

Dey A, Cederbaum AI.

Hepatology. 2007 Jun;45(6):1355-65. Erratum in: Hepatology. 2007 Aug;46(2):610.

PMID:
17538970
4.

S-adenosyl-L-methionine decreases the elevated hepatotoxicity induced by Fas agonistic antibody plus acute ethanol pretreatment in mice.

Wang X, Cederbaum AI.

Arch Biochem Biophys. 2008 Sep 1;477(1):1-11. doi: 10.1016/j.abb.2008.04.033. Epub 2008 Apr 30.

PMID:
18482574
5.

Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole.

Lu Y, Wang X, Cederbaum AI.

Am J Physiol Gastrointest Liver Physiol. 2005 Aug;289(2):G308-19. Epub 2005 Apr 21.

7.

A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1.

Zhuge J.

Mol Cell Biochem. 2008 Jul;314(1-2):105-12. doi: 10.1007/s11010-008-9770-0. Epub 2008 Apr 15.

PMID:
18414994
8.

Inhibition of the mitochondrial permeability transition by cyclosporin A prevents pyrazole plus lipopolysaccharide-induced liver injury in mice.

Zhuge J, Cederbaum AI.

Free Radic Biol Med. 2009 Feb 1;46(3):406-13. doi: 10.1016/j.freeradbiomed.2008.10.037. Epub 2008 Oct 31.

9.

Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells.

Wu D, Cederbaum AI.

Am J Physiol Gastrointest Liver Physiol. 2006 Apr;290(4):G674-84. Epub 2005 Nov 23.

10.

Role of nitric oxide and nuclear factor-kappaB in the CYP2E1 potentiation of tumor necrosis factor alpha hepatotoxicity in mice.

Wu D, Xu C, Cederbaum A.

Free Radic Biol Med. 2009 Feb 15;46(4):480-91. doi: 10.1016/j.freeradbiomed.2008.11.001. Epub 2008 Nov 19.

PMID:
19063961
11.

CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment.

Cederbaum AI.

Drug Metabol Drug Interact. 2012;27(3):125-44. doi: 10.1515/dmdi-2012-0014. Review.

PMID:
23104821
12.

Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency.

Lu Y, Gong P, Cederbaum AI.

Toxicology. 2008 Oct 30;252(1-3):9-16. doi: 10.1016/j.tox.2008.07.058. Epub 2008 Aug 3.

13.
14.

Depletion of S-adenosyl-l-methionine with cycloleucine potentiates cytochrome P450 2E1 toxicity in primary rat hepatocytes.

Zhuge J, Cederbaum AI.

Arch Biochem Biophys. 2007 Oct 15;466(2):177-85. Epub 2007 Jun 15.

15.
17.

S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver.

Bailey SM, Robinson G, Pinner A, Chamlee L, Ulasova E, Pompilius M, Page GP, Chhieng D, Jhala N, Landar A, Kharbanda KK, Ballinger S, Darley-Usmar V.

Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G857-67. Epub 2006 Jul 6.

18.
19.

Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity.

Wu D, Cederbaum A.

Toxicol Appl Pharmacol. 2006 Oct 15;216(2):282-92. Epub 2006 Jul 1.

PMID:
16938321
20.

Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase.

Wang X, Lu Y, Xie B, Cederbaum AI.

Free Radic Biol Med. 2009 Sep 1;47(5):518-28. doi: 10.1016/j.freeradbiomed.2009.05.021. Epub 2009 May 27.

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