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Items: 1 to 20 of 56

1.

Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3.

Mariño G, Salvador-Montoliu N, Fueyo A, Knecht E, Mizushima N, López-Otín C.

J Biol Chem. 2007 Jun 22;282(25):18573-83. Epub 2007 Apr 17.

2.

Autophagy, proteases and the sense of balance.

Cabrera S, Mariño G, Fernández AF, López-Otín C.

Autophagy. 2010 Oct;6(7):961-3. doi: 10.4161/auto.6.7.13065. Epub 2010 Oct 19.

PMID:
20724821
3.

Tagged ATG8-Coding Constructs for the In Vitro and In Vivo Assessment of ATG4 Activity.

López-Otín C, Mariño G.

Methods Enzymol. 2017;587:189-205. doi: 10.1016/bs.mie.2016.11.001. Epub 2016 Dec 5.

PMID:
28253955
4.
5.

Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy.

Mariño G, Uría JA, Puente XS, Quesada V, Bordallo J, López-Otín C.

J Biol Chem. 2003 Feb 7;278(6):3671-8. Epub 2002 Nov 21.

6.

Transient receptor potential vanilloid 1 activation induces autophagy in thymocytes through ROS-regulated AMPK and Atg4C pathways.

Farfariello V, Amantini C, Santoni G.

J Leukoc Biol. 2012 Sep;92(3):421-31. doi: 10.1189/jlb.0312123. Epub 2012 Jun 29.

PMID:
22753949
7.

ATM kinase sustains breast cancer stem-like cells by promoting ATG4C expression and autophagy.

Antonelli M, Strappazzon F, Arisi I, Brandi R, D'Onofrio M, Sambucci M, Manic G, Vitale I, Barilà D, Stagni V.

Oncotarget. 2017 Mar 28;8(13):21692-21709. doi: 10.18632/oncotarget.15537.

8.

The functional and pathologic relevance of autophagy proteases.

Fernández ÁF, López-Otín C.

J Clin Invest. 2015 Jan;125(1):33-41. doi: 10.1172/JCI73940. Epub 2015 Jan 2. Review.

9.

Synthetic substrates for measuring activity of autophagy proteases: autophagins (Atg4).

Shu CW, Drag M, Bekes M, Zhai D, Salvesen GS, Reed JC.

Autophagy. 2010 Oct;6(7):936-47. doi: 10.4161/auto.6.7.13075. Epub 2010 Oct 19.

10.

Unraveling the roles of Atg4 proteases from autophagy modulation to targeted cancer therapy.

Zhang L, Li J, Ouyang L, Liu B, Cheng Y.

Cancer Lett. 2016 Apr 1;373(1):19-26. doi: 10.1016/j.canlet.2016.01.022. Epub 2016 Jan 19. Review.

PMID:
26805760
11.

Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates.

Li M, Hou Y, Wang J, Chen X, Shao ZM, Yin XM.

J Biol Chem. 2011 Mar 4;286(9):7327-38. doi: 10.1074/jbc.M110.199059. Epub 2010 Dec 22.

12.

A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L.

Hemelaar J, Lelyveld VS, Kessler BM, Ploegh HL.

J Biol Chem. 2003 Dec 19;278(51):51841-50. Epub 2003 Oct 6.

13.

Autophagy is essential for mouse sense of balance.

Mariño G, Fernández AF, Cabrera S, Lundberg YW, Cabanillas R, Rodríguez F, Salvador-Montoliu N, Vega JA, Germanà A, Fueyo A, Freije JM, López-Otín C.

J Clin Invest. 2010 Jul;120(7):2331-44. doi: 10.1172/JCI42601. Epub 2010 Jun 23.

14.

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4.

Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z.

EMBO J. 2007 Apr 4;26(7):1749-60. Epub 2007 Mar 8.

15.

The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells.

Lu Z, Luo RZ, Lu Y, Zhang X, Yu Q, Khare S, Kondo S, Kondo Y, Yu Y, Mills GB, Liao WS, Bast RC Jr.

J Clin Invest. 2008 Dec;118(12):3917-29. doi: 10.1172/JCI35512. Epub 2008 Nov 20.

16.

The lipoatrophic caveolin-1 deficient mouse model reveals autophagy in mature adipocytes.

Le Lay S, Briand N, Blouin CM, Chateau D, Prado C, Lasnier F, Le Liepvre X, Hajduch E, Dugail I.

Autophagy. 2010 Aug;6(6):754-63. Epub 2010 Aug 3.

PMID:
20574167
17.

The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers.

Kumanomidou T, Mizushima T, Komatsu M, Suzuki A, Tanida I, Sou YS, Ueno T, Kominami E, Tanaka K, Yamane T.

J Mol Biol. 2006 Jan 27;355(4):612-8. Epub 2005 Nov 28.

PMID:
16325851
18.

The role of autophagy during the early neonatal starvation period.

Kuma A, Hatano M, Matsui M, Yamamoto A, Nakaya H, Yoshimori T, Ohsumi Y, Tokuhisa T, Mizushima N.

Nature. 2004 Dec 23;432(7020):1032-6. Epub 2004 Nov 3.

PMID:
15525940
19.

Induction of autophagy and autophagic cell death in damaged neural tissue after acute spinal cord injury in mice.

Kanno H, Ozawa H, Sekiguchi A, Yamaya S, Itoi E.

Spine (Phila Pa 1976). 2011 Oct 15;36(22):E1427-34. doi: 10.1097/BRS.0b013e3182028c3a.

PMID:
21304420
20.

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