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Items: 1 to 20 of 67

1.

Evolving proteins in mammalian cells using somatic hypermutation.

Wang L, Tsien RY.

Nat Protoc. 2006;1(3):1346-50.

PMID:
17406421
2.

Clonal instability of V region hypermutation in the Ramos Burkitt's lymphoma cell line.

Zhang W, Bardwell PD, Woo CJ, Poltoratsky V, Scharff MD, Martin A.

Int Immunol. 2001 Sep;13(9):1175-84.

PMID:
11526098
3.

Protein evolution by hypermutation and selection in the B cell line DT40.

Arakawa H, Kudo H, Batrak V, Caldwell RB, Rieger MA, Ellwart JW, Buerstedde JM.

Nucleic Acids Res. 2008 Jan;36(1):e1. Epub 2007 Dec 11.

4.

Evolution of new nonantibody proteins via iterative somatic hypermutation.

Wang L, Jackson WC, Steinbach PA, Tsien RY.

Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16745-9. Epub 2004 Nov 19.

5.

Directed molecular evolution by somatic hypermutation.

Wang CL, Yang DC, Wabl M.

Protein Eng Des Sel. 2004 Sep;17(9):659-64. Epub 2004 Oct 29.

PMID:
15516361
7.

Possible contribution of DNase gamma to immunoglobulin V gene diversification.

Okamoto N, Okamoto M, Araki S, Arakawa H, Mizuta R, Kitamura D.

Immunol Lett. 2009 Jun 30;125(1):22-30. doi: 10.1016/j.imlet.2009.05.005. Epub 2009 Jun 6.

PMID:
19501119
8.

Biotechnology and the chicken B cell line DT40.

Bachl J, Caldwell RB, Buerstedde JM.

Cytogenet Genome Res. 2007;117(1-4):189-94.

PMID:
17675859
9.

Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein.

Shaner NC, Campbell RE, Steinbach PA, Giepmans BN, Palmer AE, Tsien RY.

Nat Biotechnol. 2004 Dec;22(12):1567-72. Epub 2004 Nov 21.

PMID:
15558047
10.

Biochemistry. Immune cells speed the evolution of novel proteins.

Service RF.

Science. 2004 Nov 26;306(5701):1457. No abstract available.

PMID:
15567823
11.

Method for generation of human hyperdiversified antibody fragment library.

Mondon P, Souyris N, Douchy L, Crozet F, Bouayadi K, Kharrat H.

Biotechnol J. 2007 Jan;2(1):76-82.

PMID:
17225253
12.

DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination.

Hackney JA, Misaghi S, Senger K, Garris C, Sun Y, Lorenzo MN, Zarrin AA.

Adv Immunol. 2009;101:163-89. doi: 10.1016/S0065-2776(08)01005-5. Review.

PMID:
19231595
13.

Matching of oligoclonal immunoglobulin transcriptomes and proteomes of cerebrospinal fluid in multiple sclerosis.

Obermeier B, Mentele R, Malotka J, Kellermann J, Kümpfel T, Wekerle H, Lottspeich F, Hohlfeld R, Dornmair K.

Nat Med. 2008 Jun;14(6):688-93. doi: 10.1038/nm1714. Epub 2008 May 18.

PMID:
18488038
14.

Usefulness of a Darwinian system in a biotechnological application: evolution of optical window fluorescent protein variants under selective pressure.

Schoetz U, Deliolanis NC, Ng D, Pauli J, Resch-Genger U, Kühn E, Heuer S, Beisker W, Köster RW, Zitzelsberger H, Caldwell RB.

PLoS One. 2014 Sep 5;9(9):e107069. doi: 10.1371/journal.pone.0107069. eCollection 2014.

15.

Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation.

Chatterji M, Unniraman S, McBride KM, Schatz DG.

J Immunol. 2007 Oct 15;179(8):5274-80.

16.

Fast directed evolution of non-immunoglobulin proteins by somatic hypermutation in immune cells.

Heinis C, Johnsson K.

Chembiochem. 2005 May;6(5):804-6. No abstract available.

PMID:
15770622
17.

Engineering of a monomeric fluorescent protein AsGFP499 and its applications in a dual translocation and transcription assay.

Tasdemir A, Khan F, Jowitt TA, Iuzzolino L, Lohmer S, Corazza S, Schmidt TJ.

Protein Eng Des Sel. 2008 Oct;21(10):613-22. doi: 10.1093/protein/gzn040. Epub 2008 Aug 1.

PMID:
18676975
18.

Antibody repertoire development in the sheep.

Jenne CN, Kennedy LJ, Reynolds JD.

Dev Comp Immunol. 2006;30(1-2):165-74. Review.

PMID:
16083958
19.

Exploration of factors affecting the onset and maturation course of follicular lymphoma through simulations of the germinal center.

Fenwick MK, Escobedo FA.

Bull Math Biol. 2009 Aug;71(6):1432-62. doi: 10.1007/s11538-009-9408-8. Epub 2009 May 2.

PMID:
19412639
20.

Two levels of protection for the B cell genome during somatic hypermutation.

Liu M, Duke JL, Richter DJ, Vinuesa CG, Goodnow CC, Kleinstein SH, Schatz DG.

Nature. 2008 Feb 14;451(7180):841-5. doi: 10.1038/nature06547.

PMID:
18273020

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