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Items: 1 to 20 of 106


The metalloprotease meprinbeta processes E-cadherin and weakens intercellular adhesion.

Huguenin M, Müller EJ, Trachsel-Rösmann S, Oneda B, Ambort D, Sterchi EE, Lottaz D.

PLoS One. 2008 May 14;3(5):e2153. doi: 10.1371/journal.pone.0002153.


γ-Secretase-dependent cleavage of E-cadherin by staurosporine in breast cancer cells.

Yoo CB, Yun SM, Jo C, Koh YH.

Cell Commun Adhes. 2012 Feb;19(1):11-6. doi: 10.3109/15419061.2012.665969. Epub 2012 Mar 8.


Cadmium induces N-cadherin cleavage via ERK-mediated γ-secretase activation in C6 astroglia cells.

Jo C, Koh YH.

Toxicol Lett. 2013 Oct 24;222(2):117-21. doi: 10.1016/j.toxlet.2013.07.015. Epub 2013 Jul 19.


Rapid disruption of intestinal barrier function by gliadin involves altered expression of apical junctional proteins.

Sander GR, Cummins AG, Henshall T, Powell BC.

FEBS Lett. 2005 Aug 29;579(21):4851-5.


Modulation of cell adhesion molecules in various epithelial cell lines after treatment with PP2.

Calcagno AM, Fostel JM, Orchekowski RP, Alston JT, Mattes WB, Siahaan TJ, Ware JA.

Mol Pharm. 2005 May-Jun;2(3):170-84.


Presenilin 1/gamma-secretase is associated with cadmium-induced E-cadherin cleavage and COX-2 gene expression in T47D breast cancer cells.

Park CS, Kim OS, Yun SM, Jo SA, Jo I, Koh YH.

Toxicol Sci. 2008 Dec;106(2):413-22. doi: 10.1093/toxsci/kfn197. Epub 2008 Sep 12.


Bacteroides fragilis toxin stimulates intestinal epithelial cell shedding and gamma-secretase-dependent E-cadherin cleavage.

Wu S, Rhee KJ, Zhang M, Franco A, Sears CL.

J Cell Sci. 2007 Jun 1;120(Pt 11):1944-52. Epub 2007 May 15. Erratum in: J Cell Sci. 2007 Oct 15;120(Pt 20):3713.


Cleavage and shedding of E-cadherin after induction of apoptosis.

Steinhusen U, Weiske J, Badock V, Tauber R, Bommert K, Huber O.

J Biol Chem. 2001 Feb 16;276(7):4972-80. Epub 2000 Nov 13.


The role of calpain in the proteolytic cleavage of E-cadherin in prostate and mammary epithelial cells.

Rios-Doria J, Day KC, Kuefer R, Rashid MG, Chinnaiyan AM, Rubin MA, Day ML.

J Biol Chem. 2003 Jan 10;278(2):1372-9. Epub 2002 Oct 19.


N-cadherin mediates endocytosis of Candida albicans by endothelial cells.

Phan QT, Fratti RA, Prasadarao NV, Edwards JE Jr, Filler SG.

J Biol Chem. 2005 Mar 18;280(11):10455-61. Epub 2005 Jan 4.


theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability.

Banan A, Zhang LJ, Shaikh M, Fields JZ, Choudhary S, Forsyth CB, Farhadi A, Keshavarzian A.

J Pharmacol Exp Ther. 2005 Jun;313(3):962-82.


PAR2 activation interrupts E-cadherin adhesion and compromises the airway epithelial barrier: protective effect of beta-agonists.

Winter MC, Shasby SS, Ries DR, Shasby DM.

Am J Physiol Lung Cell Mol Physiol. 2006 Oct;291(4):L628-35. Epub 2006 May 19.


The role of an 80 kDa fragment of E-cadherin in the metastatic progression of prostate cancer.

Kuefer R, Hofer MD, Gschwend JE, Pienta KJ, Sanda MG, Chinnaiyan AM, Rubin MA, Day ML.

Clin Cancer Res. 2003 Dec 15;9(17):6447-52.


Extracellular cleavage of E-cadherin by leukocyte elastase during acute experimental pancreatitis in rats.

Mayerle J, Schnekenburger J, Krüger B, Kellermann J, Ruthenbürger M, Weiss FU, Nalli A, Domschke W, Lerch MM.

Gastroenterology. 2005 Oct;129(4):1251-67.


Down-regulation of E-cadherin in human bronchial epithelial cells leads to epidermal growth factor receptor-dependent Th2 cell-promoting activity.

Heijink IH, Kies PM, Kauffman HF, Postma DS, van Oosterhout AJ, Vellenga E.

J Immunol. 2007 Jun 15;178(12):7678-85.


Interleukin-1 receptor type 1 is a substrate for gamma-secretase-dependent regulated intramembrane proteolysis.

Elzinga BM, Twomey C, Powell JC, Harte F, McCarthy JV.

J Biol Chem. 2009 Jan 16;284(3):1394-409. doi: 10.1074/jbc.M803108200. Epub 2008 Nov 7.


Degradation of human subendothelial extracellular matrix by proteinase-secreting Candida albicans.

Morschhäuser J, Virkola R, Korhonen TK, Hacker J.

FEMS Microbiol Lett. 1997 Aug 15;153(2):349-55.


Acid stimulates E-cadherin surface expression on gastric epithelial cells to stabilize barrier functions via influx of calcium.

Mizuno M, Okayama N, Kasugai K, Yoshida T, Miyata M, Nitta M, Kataoka H, Akita S, Joh T, Itoh M, Asai K, Kato T.

Eur J Gastroenterol Hepatol. 2001 Feb;13(2):127-36.


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