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Items: 1 to 20 of 229

1.
2.

Inhibition of bile acid transport across Na+/taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs.

Mita S, Suzuki H, Akita H, Hayashi H, Onuki R, Hofmann AF, Sugiyama Y.

Drug Metab Dispos. 2006 Sep;34(9):1575-81. Epub 2006 Jun 7.

3.
4.

Interaction of fluvastatin with the liver-specific Na+ -dependent taurocholate cotransporting polypeptide (NTCP).

Greupink R, Dillen L, Monshouwer M, Huisman MT, Russel FG.

Eur J Pharm Sci. 2011 Nov 20;44(4):487-96. doi: 10.1016/j.ejps.2011.09.009. Epub 2011 Sep 16.

PMID:
21945488
5.

Evaluation of the endothelin receptor antagonists ambrisentan, bosentan, macitentan, and sitaxsentan as hepatobiliary transporter inhibitors and substrates in sandwich-cultured human hepatocytes.

Lepist EI, Gillies H, Smith W, Hao J, Hubert C, St Claire RL 3rd, Brouwer KR, Ray AS.

PLoS One. 2014 Jan 30;9(1):e87548. doi: 10.1371/journal.pone.0087548. eCollection 2014.

6.

Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump.

Mita S, Suzuki H, Akita H, Stieger B, Meier PJ, Hofmann AF, Sugiyama Y.

Am J Physiol Gastrointest Liver Physiol. 2005 Jan;288(1):G159-67. Epub 2004 Aug 5.

7.

Ritonavir, saquinavir, and efavirenz, but not nevirapine, inhibit bile acid transport in human and rat hepatocytes.

McRae MP, Lowe CM, Tian X, Bourdet DL, Ho RH, Leake BF, Kim RB, Brouwer KL, Kashuba AD.

J Pharmacol Exp Ther. 2006 Sep;318(3):1068-75. Epub 2006 May 23.

9.

Regulation of plasma membrane localization of the Na+-taurocholate cotransporting polypeptide (Ntcp) by hyperosmolarity and tauroursodeoxycholate.

Sommerfeld A, Mayer PG, Cantore M, Häussinger D.

J Biol Chem. 2015 Oct 2;290(40):24237-54. doi: 10.1074/jbc.M115.666883. Epub 2015 Aug 25. Erratum in: J Biol Chem. 2016 Jul 22;291(30):15908.

10.
11.

Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice.

Slijepcevic D, Kaufman C, Wichers CG, Gilglioni EH, Lempp FA, Duijst S, de Waart DR, Elferink RP, Mier W, Stieger B, Beuers U, Urban S, van de Graaf SF.

Hepatology. 2015 Jul;62(1):207-19. doi: 10.1002/hep.27694. Epub 2015 May 8.

12.

Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury.

Li X, Zhong K, Guo Z, Zhong D, Chen X.

Drug Metab Dispos. 2015 Nov;43(11):1751-9. doi: 10.1124/dmd.115.064121. Epub 2015 Aug 14.

13.

PKC{epsilon}-dependent and -independent effects of taurolithocholate on PI3K/PKB pathway and taurocholate uptake in HuH-NTCP cell line.

Schonhoff CM, Yamazaki A, Hohenester S, Webster CR, Bouscarel B, Anwer MS.

Am J Physiol Gastrointest Liver Physiol. 2009 Dec;297(6):G1259-67. doi: 10.1152/ajpgi.00177.2009. Epub 2009 Oct 8.

14.

Use of cassette dosing in sandwich-cultured rat and human hepatocytes to identify drugs that inhibit bile acid transport.

Wolf KK, Vora S, Webster LO, Generaux GT, Polli JW, Brouwer KL.

Toxicol In Vitro. 2010 Feb;24(1):297-309. doi: 10.1016/j.tiv.2009.08.009. Epub 2009 Aug 23.

15.

Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB.

Gastroenterology. 2006 May;130(6):1793-806. Epub 2006 Mar 6.

PMID:
16697742
16.

Na+-taurocholate cotransporting polypeptide (NTCP/SLC10A1) ortholog in the marine skate Leucoraja erinacea is not a physiological bile salt transporter.

Yu D, Zhang H, Lionarons DA, Boyer JL, Cai SY.

Am J Physiol Regul Integr Comp Physiol. 2017 Apr 1;312(4):R477-R484. doi: 10.1152/ajpregu.00302.2016. Epub 2017 Jan 11.

17.

Electrophysiological characterization of human Na⁺/taurocholate cotransporting polypeptide (hNTCP) heterologously expressed in Xenopus laevis oocytes.

Masuda M, Ichikawa Y, Shimono K, Shimizu M, Tanaka Y, Nara T, Miyauchi S.

Arch Biochem Biophys. 2014 Nov 15;562:115-21. doi: 10.1016/j.abb.2014.08.010. Epub 2014 Aug 27.

PMID:
25168282
18.

Viral entry of hepatitis B and D viruses and bile salts transportation share common molecular determinants on sodium taurocholate cotransporting polypeptide.

Yan H, Peng B, Liu Y, Xu G, He W, Ren B, Jing Z, Sui J, Li W.

J Virol. 2014 Mar;88(6):3273-84. doi: 10.1128/JVI.03478-13. Epub 2014 Jan 3.

19.

Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes.

Ni Y, Lempp FA, Mehrle S, Nkongolo S, Kaufman C, Fälth M, Stindt J, Königer C, Nassal M, Kubitz R, Sültmann H, Urban S.

Gastroenterology. 2014 Apr;146(4):1070-83. doi: 10.1053/j.gastro.2013.12.024. Epub 2013 Dec 19.

PMID:
24361467
20.

Contribution of high basolateral bile salt efflux to the lack of hepatotoxicity in rat in response to drugs inducing cholestasis in human.

Jemnitz K, Veres Z, Vereczkey L.

Toxicol Sci. 2010 May;115(1):80-8. doi: 10.1093/toxsci/kfq044. Epub 2010 Feb 10.

PMID:
20147439

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