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Items: 1 to 20 of 176

1.

Two synergistic activation mechanisms of alpha2beta1 integrin-mediated collagen binding.

Connors WL, Jokinen J, White DJ, Puranen JS, Kankaanpää P, Upla P, Tulla M, Johnson MS, Heino J.

J Biol Chem. 2007 May 11;282(19):14675-83. Epub 2007 Mar 19.

2.

TPA primes alpha2beta1 integrins for cell adhesion.

Tulla M, Helenius J, Jokinen J, Taubenberger A, Müller DJ, Heino J.

FEBS Lett. 2008 Oct 15;582(23-24):3520-4. doi: 10.1016/j.febslet.2008.09.022. Epub 2008 Sep 18. Erratum in: FEBS Lett. 2008 Nov 26;582(28):3966.

3.

Activation of protein kinase C by phorbol esters modulates alpha2beta1 integrin on MCF-7 breast cancer cells.

Rosfjord EC, Maemura M, Johnson MD, Torri JA, Akiyama SK, Woods VL Jr, Dickson RB.

Exp Cell Res. 1999 Apr 10;248(1):260-71.

PMID:
10094832
5.

Molecular mechanism of alpha2beta1 integrin interaction with human echovirus 1.

Jokinen J, White DJ, Salmela M, Huhtala M, Käpylä J, Sipilä K, Puranen JS, Nissinen L, Kankaanpää P, Marjomäki V, Hyypiä T, Johnson MS, Heino J.

EMBO J. 2010 Jan 6;29(1):196-208. doi: 10.1038/emboj.2009.326. Epub 2009 Nov 19.

6.

Syndecan-1 supports integrin alpha2beta1-mediated adhesion to collagen.

Vuoriluoto K, Jokinen J, Kallio K, Salmivirta M, Heino J, Ivaska J.

Exp Cell Res. 2008 Nov 1;314(18):3369-81. doi: 10.1016/j.yexcr.2008.07.005. Epub 2008 Jul 15.

PMID:
18657535
7.

Novel α2β1 integrin inhibitors reveal that integrin binding to collagen under shear stress conditions does not require receptor preactivation.

Nissinen L, Koivunen J, Käpylä J, Salmela M, Nieminen J, Jokinen J, Sipilä K, Pihlavisto M, Pentikäinen OT, Marjamäki A, Heino J.

J Biol Chem. 2012 Dec 28;287(53):44694-702. doi: 10.1074/jbc.M111.309450. Epub 2012 Nov 6.

8.

Two functional active conformations of the integrin {alpha}2{beta}1, depending on activation condition and cell type.

Van de Walle GR, Vanhoorelbeke K, Majer Z, Illyés E, Baert J, Pareyn I, Deckmyn H.

J Biol Chem. 2005 Nov 4;280(44):36873-82. Epub 2005 Aug 15.

9.

Integrin alpha2beta1 is a receptor for the cartilage matrix protein chondroadherin.

Camper L, Heinegârd D, Lundgren-Akerlund E.

J Cell Biol. 1997 Sep 8;138(5):1159-67.

11.

Interactions of primary fibroblasts and keratinocytes with extracellular matrix proteins: contribution of alpha2beta1 integrin.

Zhang ZG, Bothe I, Hirche F, Zweers M, Gullberg D, Pfitzer G, Krieg T, Eckes B, Aumailley M.

J Cell Sci. 2006 May 1;119(Pt 9):1886-95.

12.

Transcription of alpha2 integrin gene in osteosarcoma cells is enhanced by tumor promoters.

Nissinen L, Westermarck J, Koivisto L, Kähäri VM, Heino J.

Exp Cell Res. 1998 Aug 25;243(1):1-10.

PMID:
9716443
14.

The fibril-associated collagen IX provides a novel mechanism for cell adhesion to cartilaginous matrix.

Käpylä J, Jäälinoja J, Tulla M, Ylöstalo J, Nissinen L, Viitasalo T, Vehviläinen P, Marjomäki V, Nykvist P, Säämänen AM, Farndale RW, Birk DE, Ala-Kokko L, Heino J.

J Biol Chem. 2004 Dec 3;279(49):51677-87. Epub 2004 Sep 21.

15.

Platelet alpha2beta1 integrin activation: contribution of ligand internalization and the alpha2-cytoplasmic domain.

Wang Z, Leisner TM, Parise LV.

Blood. 2003 Aug 15;102(4):1307-15. Epub 2003 May 8.

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Integrin-mediated cell adhesion to type I collagen fibrils.

Jokinen J, Dadu E, Nykvist P, Käpylä J, White DJ, Ivaska J, Vehviläinen P, Reunanen H, Larjava H, Häkkinen L, Heino J.

J Biol Chem. 2004 Jul 23;279(30):31956-63. Epub 2004 May 15.

20.

Monoclonal antibodies identify residues 199-216 of the integrin alpha2 vWFA domain as a functionally important region within alpha2beta1.

Tuckwell DS, Smith L, Korda M, Askari JA, Santoso S, Barnes MJ, Farndale RW, Humphries MJ.

Biochem J. 2000 Sep 1;350 Pt 2:485-93.

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