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Items: 1 to 20 of 73


The cyclin-dependent kinase Cdk5 controls multiple aspects of axon patterning in vivo.

Connell-Crowley L, Le Gall M, Vo DJ, Giniger E.

Curr Biol. 2000 May 18;10(10):599-602.


Absence of the Cdk5 activator p35 causes adult-onset neurodegeneration in the central brain of Drosophila.

Trunova S, Giniger E.

Dis Model Mech. 2012 Mar;5(2):210-9. doi: 10.1242/dmm.008847. Epub 2011 Dec 21.


Abl deregulates Cdk5 kinase activity and subcellular localization in Drosophila neurodegeneration.

Lin H, Lin TY, Juang JL.

Cell Death Differ. 2007 Mar;14(3):607-15. Epub 2006 Aug 25.


Cdk5 regulates the size of an axon initial segment-like compartment in mushroom body neurons of the Drosophila central brain.

Trunova S, Baek B, Giniger E.

J Neurosci. 2011 Jul 20;31(29):10451-62. doi: 10.1523/JNEUROSCI.0117-11.2011.


Transient enhanced expression of Cdk5 activator p25 after acute and chronic d-amphetamine administration.

Mlewski EC, Krapacher FA, Ferreras S, Paglini G.

Ann N Y Acad Sci. 2008 Oct;1139:89-102. doi: 10.1196/annals.1432.039.


Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain.

Ohshima T, Ogawa M, Veeranna, Hirasawa M, Longenecker G, Ishiguro K, Pant HC, Brady RO, Kulkarni AB, Mikoshiba K.

Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2764-9. Epub 2001 Feb 13.


p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment.

Ko J, Humbert S, Bronson RT, Takahashi S, Kulkarni AB, Li E, Tsai LH.

J Neurosci. 2001 Sep 1;21(17):6758-71.


Drosophila cdk5 is needed for locomotive behavior and NMJ elaboration, but seems dispensable for synaptic transmission.

Kissler AE, Pettersson N, Frölich A, Sigrist SJ, Suter B.

Dev Neurobiol. 2009 May;69(6):365-77. doi: 10.1002/dneu.20711.


Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase.

Kwon YT, Gupta A, Zhou Y, Nikolic M, Tsai LH.

Curr Biol. 2000 Apr 6;10(7):363-72.


p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.

Patrick GN, Zhou P, Kwon YT, Howley PM, Tsai LH.

J Biol Chem. 1998 Sep 11;273(37):24057-64.


The axon guidance function of Rap1 small GTPase is independent of PlexA RasGAP activity in Drosophila.

Yang DS, Roh S, Jeong S.

Dev Biol. 2016 Oct 15;418(2):258-67. doi: 10.1016/j.ydbio.2016.08.026. Epub 2016 Aug 24.


Role of cyclin-dependent kinase 5 and its activator P35 in local axon and growth cone stabilization.

Hahn CM, Kleinholz H, Koester MP, Grieser S, Thelen K, Pollerberg GE.

Neuroscience. 2005;134(2):449-65.


The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila.

Kannan R, Song JK, Karpova T, Clarke A, Shivalkar M, Wang B, Kotlyanskaya L, Kuzina I, Gu Q, Giniger E.

Development. 2017 Feb 1;144(3):487-498. doi: 10.1242/dev.143776. Epub 2017 Jan 13.


The fruitless gene is required for the proper formation of axonal tracts in the embryonic central nervous system of Drosophila.

Song HJ, Billeter JC, Reynaud E, Carlo T, Spana EP, Perrimon N, Goodwin SF, Baker BS, Taylor BJ.

Genetics. 2002 Dec;162(4):1703-24.


Microtubule association of the neuronal p35 activator of Cdk5.

Hou Z, Li Q, He L, Lim HY, Fu X, Cheung NS, Qi DX, Qi RZ.

J Biol Chem. 2007 Jun 29;282(26):18666-70. Epub 2007 May 9.


The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance.

Weng YL, Liu N, DiAntonio A, Broihier HT.

J Neurosci. 2011 Mar 23;31(12):4421-33. doi: 10.1523/JNEUROSCI.5230-10.2011.

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