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Items: 1 to 20 of 89

1.

HIV-1 integrase inhibitors are substrates for the multidrug transporter MDR1-P-glycoprotein.

Cianfriglia M, Dupuis ML, Molinari A, Verdoliva A, Costi R, Galluzzo CM, Andreotti M, Cara A, Di Santo R, Palmisano L.

Retrovirology. 2007 Mar 7;4:17.

2.

Raltegravir does not revert efflux activity of MDR1-P-glycoprotein in human MDR cells.

Dupuis ML, Ascione A, Palmisano L, Vella S, Cianfriglia M.

BMC Pharmacol Toxicol. 2013 Sep 20;14:47. doi: 10.1186/2050-6511-14-47.

3.

HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

Lee CG, Gottesman MM, Cardarelli CO, Ramachandra M, Jeang KT, Ambudkar SV, Pastan I, Dey S.

Biochemistry. 1998 Mar 17;37(11):3594-601.

PMID:
9530286
4.
5.

Determination of P-glycoprotein surface expression and functional ability after in vitro treatment with darunavir or raltegravir in lymphocytes of healthy donors.

Tempestilli M, Gentilotti E, Tommasi C, Nicastri E, Martini F, De Nardo P, Narciso P, Pucillo LP.

Int Immunopharmacol. 2013 Aug;16(4):492-7. doi: 10.1016/j.intimp.2013.05.003. Epub 2013 May 23.

PMID:
23707228
6.
7.

Induction of multidrug resistance in MOLT-4 cells by anticancer agents is closely related to increased expression of functional P-glycoprotein and MDR1 mRNA.

Liu ZL, Onda K, Tanaka S, Toma T, Hirano T, Oka K.

Cancer Chemother Pharmacol. 2002 May;49(5):391-7. Epub 2002 Feb 14.

PMID:
11976833
8.

The molecular interaction of a copper chelate with human P-glycoprotein.

Ghosh RD, Chakraborty P, Banerjee K, Adhikary A, Sarkar A, Chatterjee M, Das T, Choudhuri SK.

Mol Cell Biochem. 2012 May;364(1-2):309-20. doi: 10.1007/s11010-012-1232-z. Epub 2012 Jan 19.

PMID:
22258826
9.

Reversal of drug resistance in P-glycoprotein-expressing T-cell acute lymphoblastic CEM leukemia cells by copper N-(2-hydroxy acetophenone) glycinate and oxalyl bis (N-phenyl) hydroxamic acid.

Majumder S, Dutta P, Mukherjee P, Datta ER, Efferth T, Bhattacharya S, Choudhuri SK.

Cancer Lett. 2006 Nov 28;244(1):16-23. Epub 2006 Jan 10.

PMID:
16410038
10.
11.

BIBW22 BS, potent multidrug resistance-reversing agent, binds directly to P-glycoprotein and accumulates in drug-resistant cells.

Liu Z, Lheureux F, Pouliot JF, Heckel A, Bamberger U, Georges E.

Mol Pharmacol. 1996 Sep;50(3):482-92.

PMID:
8794885
12.

Mitochondrial localization and activity of P-glycoprotein in doxorubicin-resistant K562 cells.

Munteanu E, Verdier M, Grandjean-Forestier F, Stenger C, Jayat-Vignoles C, Huet S, Robert J, Ratinaud MH.

Biochem Pharmacol. 2006 Apr 14;71(8):1162-74. Epub 2006 Feb 24.

PMID:
16499877
13.

Reversal of P-gp mediated multidrug resistance in-vitro and in-vivo by FG020318.

Chen LM, Liang YJ, Ruan JW, Ding Y, Wang XW, Shi Z, Gu LQ, Yang XP, Fu LW.

J Pharm Pharmacol. 2004 Aug;56(8):1061-6.

PMID:
15285852
14.

Effect of MDR modulators verapamil and promethazine on gene expression levels of MDR1 and MRP1 in doxorubicin-resistant MCF-7 cells.

Dönmez Y, Akhmetova L, İşeri ÖD, Kars MD, Gündüz U.

Cancer Chemother Pharmacol. 2011 Apr;67(4):823-8. doi: 10.1007/s00280-010-1385-y. Epub 2010 Jun 19.

PMID:
20563580
15.

The novel anthracycline annamycin is not affected by P-glycoprotein-related multidrug resistance: comparison with idarubicin and doxorubicin in HL-60 leukemia cell lines.

Consoli U, Priebe W, Ling YH, Mahadevia R, Griffin M, Zhao S, Perez-Soler R, Andreeff M.

Blood. 1996 Jul 15;88(2):633-44.

16.

In vitro and in vivo modulation of MDR1/P-glycoprotein in HIV-infected patients administered highly active antiretroviral therapy and liposomal doxorubicin.

Lucia MB, Rutella S, Leone G, Larocca LM, Vella S, Cauda R.

J Acquir Immune Defic Syndr. 2002 Aug 1;30(4):369-78.

PMID:
12138343
17.

Quantitation of doxorubicin uptake, efflux, and modulation of multidrug resistance (MDR) in MDR human cancer cells.

Shen F, Chu S, Bence AK, Bailey B, Xue X, Erickson PA, Montrose MH, Beck WT, Erickson LC.

J Pharmacol Exp Ther. 2008 Jan;324(1):95-102. Epub 2007 Oct 18.

18.

P-glycoprotein as multidrug transporter: a critical review of current multidrug resistant cell lines.

Nielsen D, Skovsgaard T.

Biochim Biophys Acta. 1992 Jul 7;1139(3):169-83. Review.

PMID:
1352705
19.

Drug efflux mediated by the human multidrug resistance P-glycoprotein is inhibited by cell swelling.

Sardini A, Mintenig GM, Valverde MA, Sepúlveda FV, Gill DR, Hyde SC, Higgins CF, McNaughton PA.

J Cell Sci. 1994 Dec;107 ( Pt 12):3281-90.

20.

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