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17339272,17975322,17671397,15885642,20363965,19182257,16129490,15342209,17048200,16441426,10845601,14579280,9398403,15384046,7543527,18621049,15569772,10092797,8898968,17569889,19781375,9378961,9144464,7542599,19729380,15353579,19535643,18855194,17989360,17051976,7525300,15565659,15374847,16282703,16126211,17667813,20007574,8026519,15953571,18669487,8104217,16966495,2832313,15307178,15207780,9743331,18988742,8397249,16236366,17487489,7523514,10092763,16221208,1849941,7875219,8566020,11902833,14975355,9647261,15544628,9079798,17981268,15652415,17507101,9670968,16027141,12230943,7875208,19249124,1531093,17122128,14515261,16423040,18775867,9531273,15626486,19959639,3136912,18421793,7908914,17484804,15380043,21041733,21659460,3156183,15621057,18793691,17229818,8081954,17609291,19637198,14762342,8383716,15599732,19077895,12218188,17898289,19800335,16478921,16382236,19031766,11329470,16165113,12428253,18178159,9605138,17626150,16565389,20498361,7774619,9498744,16101819,17868872,3116089,15114660,21127133,17899549,9469448,12208761,8894251,16101143,16415100,17109466,11606747,3082972,16911275,16265694,11224528,17003458,17898306,17850646,17942524,9144500,9145312,17439726,17369189,19794071,22385629,18805480,19540938,12209623,8383717,19100802,10515806,15705479,17003438,9120286,9165273,11414736,19667092,15221537,17301952,8096881,2423601,20543108,8405059,16793916,17112417,11286011,10354273,17175235,21108462,15884053,15916814,15162447,2830339,17051145,11485353,16571414,12115636,15193380,9045917,15240746,8943386,10469366,16061026,21263073,2582034,15246610,9498757,15249675,17309825,15767291,12697896,15824070,20393451,8992978,8287485,22204817,16970282,9613238,21045077,16935390,3082973,17291290,16874487,8301119,17310492,11991669,11390600,11911464,24030703,15946249,16337984,14579273,10384156,1560195,16699464,16482562,17853943,12407158,16141246,16876901,17295661,15254713,17161362,9126976,15671076,12154048,9510171,15007094,3930891,8360484,9384677,7970123,21268005,10477562,9058803,8007580,10715992,7957573,12847136,8811937,16917489,8906809,15275969,8089490,8496589,10072509,15827171,17629517,15781259,22503210,17643252,16890603,9574552,16185524,15778288,3500208,16764942,2404154,16413538,15963855,11477458,17434153,9438175,2416676,16956699,8964086,16285013,14699018,15297412,16373503,15860220,1762655,1848575,2454827,2577122,2514106,16552709,8805620,2107254,12646865,2972777,15361696,17412283,10672928,19379738,16106102,8468915,20349059,3016203,8156145,16619286,9686321,7682582,16324888,16534484,16021601,8814270,16636173,20802088,15864782,20971187,11956599,21540239,15805296,12667394,20579316,15536199,8482837,16866881,10612650,16761317,16792861,22144176,22133510,8992995,15184507,7759860,9794397,10554033,12649748,10833425,20719171,10680014,8165708,2942462,11932780,15897272,3891851,15611321,21159661,12115605,16253242,19751765,15229941,12676071,10897050,8189071,8021503,16441508,16484149,12717690,3499459,24704664,15627979,15985639,12594515,15780196,15808517,14745033,21116786,8482838,2459235,15963857,16085391,3031507,15127235,16151808,20381020,10421641,21349367,14612546,6178595,2118476,11133367,15320885,8144915,16797416,16388504,10358144,16120215,15214036,6975828,17083613,6427339,15776283,15163560,3920317,19543053,33197512,17981793,22050577,15114672,15944341,1768738,3264310,17142723,8168145,27264687,16549793,15302846,12704383,8558024,9551889,15520206,9368605,1643293,12381916,3263148,2479568,6607280,16078275,6417232,12811846,23876314,14515254,17301951,15899830,11465096,23720810,32868392,16618773,15295614,12198554,10383819,15345307,2459244,15921252,1977950,2984482,15493270,15193386,16271509,17266176,21752471,17219148,14975368,3257241,17460279,15696100,12039981,12186186,16110759,15983396,16387181,19680649,19723502,12417913,17028199,1387613,8977296,16019674,8223869,16449079,12731042,9195131,3492589,24507064,7963531,7865891,26219551,15872081,11292252,19118004,17938288,15990392,7835918,24816762,16436955,12125139,16936108,22108530,9507214,15345280,17312113,16163673,15689402,16900095,9264339,16955523,16606670,16078831,12745575,11292258,25867264,33128485,12459592,31017008,16623876,16445896,16525420,12709012,25154680,12115652,30804928,16355370,17911591,27424145,15214045,11564783,14681692,17274003,29100036,8806476,26105028,21481304,16500735,11551413,16781017,25310899,24401835,8229756,17045460,14607751,32281417,2451691,20442224,24890099,8609384,16790806,10604997,17095610,6956630,16708402,26484769,17785803,16773195,16884707,17309778,30541848,15942688,15913852,17403056,15780092,15739167,9485202,32527950,15815704,23405964,16307851,15134782,8021489,14633733,14636243,12941383,9842911,17116737,17212704,16098261,25047812,15476270,12882650,22119715,16212893,16039579,23711708,8476505,20592282,17195077,9413217,3108668,29516506,26694968,16791878,22906740,17126444,25027969,26885856,14871849,10198602,12626584,30446226,17032237,27390910,15640397,22767507,31037153,1360551,12516632,3494953,20484136,18417514,16375978,17174605,11821904,10685394,9087968,20453106,23328583,30972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PD-L1 partially protects renal tubular epithelial cells from the attack of CD8+ cytotoxic T cells.

Waeckerle-Men Y, Starke A, Wüthrich RP. Waeckerle-Men Y, et al. Nephrol Dial Transplant. 2007 Jun;22(6):1527-36. doi: 10.1093/ndt/gfl818. Epub 2007 Mar 5. Nephrol Dial Transplant. 2007. PMID: 17339272 Free article.

Limited costimulatory molecule expression on renal tubular epithelial cells impairs T cell activation.

Waeckerle-Men Y, Starke A, Wahl PR, Wüthrich RP. Waeckerle-Men Y, et al. Kidney Blood Press Res. 2007;30(6):421-9. doi: 10.1159/000110578. Epub 2007 Oct 26. Kidney Blood Press Res. 2007. PMID: 17975322

TGF-beta treatment modulates PD-L1 and CD40 expression in proximal renal tubular epithelial cells and enhances CD8 cytotoxic T-cell responses.

Starke A, Wüthrich RP, Waeckerle-Men Y. Starke A, et al. Nephron Exp Nephrol. 2007;107(1):e22-9. doi: 10.1159/000106506. Epub 2007 Jul 10. Nephron Exp Nephrol. 2007. PMID: 17671397

PD-L1 is expressed by human renal tubular epithelial cells and suppresses T cell cytokine synthesis.

Ding H, Wu X, Gao W. Ding H, et al. Clin Immunol. 2005 May;115(2):184-91. doi: 10.1016/j.clim.2005.01.005. Clin Immunol. 2005. PMID: 15885642

Keratinocyte-associated B7-H1 directly regulates cutaneous effector CD8+ T cell responses.

Ritprajak P, Hashiguchi M, Tsushima F, Chalermsarp N, Azuma M. Ritprajak P, et al. J Immunol. 2010 May 1;184(9):4918-25. doi: 10.4049/jimmunol.0902478. Epub 2010 Apr 2. J Immunol. 2010. PMID: 20363965

T-cell suppression by programmed cell death 1 ligand 1 on retinal pigment epithelium during inflammatory conditions.

Sugita S, Usui Y, Horie S, Futagami Y, Aburatani H, Okazaki T, Honjo T, Takeuchi M, Mochizuki M. Sugita S, et al. Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2862-70. doi: 10.1167/iovs.08-2846. Epub 2009 Jan 31. Invest Ophthalmol Vis Sci. 2009. PMID: 19182257

Triptolide inhibits B7-H1 expression on proinflammatory factor activated renal tubular epithelial cells by decreasing NF-kappaB transcription.

Chen Y, Zhang J, Li J, Zhao T, Zou L, Tang Y, Zhang X, Wu Y. Chen Y, et al. Mol Immunol. 2006 Mar;43(8):1088-98. doi: 10.1016/j.molimm.2005.07.026. Epub 2005 Aug 29. Mol Immunol. 2006. PMID: 16129490

Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis.

Schreiner B, Mitsdoerffer M, Kieseier BC, Chen L, Hartung HP, Weller M, Wiendl H. Schreiner B, et al. J Neuroimmunol. 2004 Oct;155(1-2):172-82. doi: 10.1016/j.jneuroim.2004.06.013. J Neuroimmunol. 2004. PMID: 15342209

Renal tubular epithelial expression of the coinhibitory molecule B7-DC (programmed death-1 ligand).

Zhang J, Chen Y, Li J, Zhang R, Wu Y, Zou L, Zhao T, Zhang X, Han J, Chen A, Wu Y. Zhang J, et al. J Nephrol. 2006 Jul-Aug;19(4):429-38. J Nephrol. 2006. PMID: 17048200

Tetramer-blocking assay for defining antigen-specific cytotoxic T lymphocytes using peptide-MHC tetramer.

Yokouchi H, Chamoto K, Wakita D, Noguchi D, Yamazaki K, Dosaka-Akita H, Nishimura M, Ikeda H, Nishimura T. Yokouchi H, et al. Cancer Sci. 2006 Feb;97(2):148-54. doi: 10.1111/j.1349-7006.2006.00149.x. Cancer Sci. 2006. PMID: 16441426 Free article.

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