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Differential activation of insulin receptor substrates 1 and 2 by insulin-like growth factor-activated insulin receptors.

Denley A, Carroll JM, Brierley GV, Cosgrove L, Wallace J, Forbes B, Roberts CT Jr. Denley A, et al. Mol Cell Biol. 2007 May;27(10):3569-77. doi: 10.1128/MCB.01447-06. Epub 2007 Feb 26. Mol Cell Biol. 2007. PMID: 17325037 Free PMC article.

Dual regulation of upstream binding factor 1 levels by IRS-1 and ERKs in IGF-1-receptor signaling.

Sun H, Tu X, Liu M, Baserga R. Sun H, et al. J Cell Physiol. 2007 Sep;212(3):780-6. doi: 10.1002/jcp.21072. J Cell Physiol. 2007. PMID: 17443674

Identification of structural characteristics that contribute to a difference in antiapoptotic function between human insulin and insulin-like growth factor 1 receptors.

Chen H, Yan GC, Gishizky ML. Chen H, et al. Cell Growth Differ. 1998 Nov;9(11):939-47. Cell Growth Differ. 1998. PMID: 9831246

IGF-I receptor protection from apoptosis in cells lacking the IRS proteins.

Dews M, Nishimoto I, Baserga R. Dews M, et al. Recept Signal Transduct. 1997;7(4):231-40. Recept Signal Transduct. 1997. PMID: 9633824

Differential regulation of signaling pathways for insulin and insulin-like growth factor I.

Lopaczynski W. Lopaczynski W. Acta Biochim Pol. 1999;46(1):51-60. Acta Biochim Pol. 1999. PMID: 10453981 Free article. Review.

Loss of insulin-like growth factor II receptor expression promotes growth in cancer by increasing intracellular signaling from both IGF-I and insulin receptors.

Osipo C, Dorman S, Frankfater A. Osipo C, et al. Exp Cell Res. 2001 Apr 1;264(2):388-96. doi: 10.1006/excr.2000.5121. Exp Cell Res. 2001. PMID: 11262195

In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A.

Sciacca L, Mineo R, Pandini G, Murabito A, Vigneri R, Belfiore A. Sciacca L, et al. Oncogene. 2002 Nov 28;21(54):8240-50. doi: 10.1038/sj.onc.1206058. Oncogene. 2002. PMID: 12447687

How distinct are the insulin and insulin-like growth factor I signalling systems?

Adamo M, Roberts CT Jr, LeRoith D. Adamo M, et al. Biofactors. 1992 Jan;3(3):151-7. Biofactors. 1992. PMID: 1599609 Review.

The insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase.

Martin MJ, Melnyk N, Pollard M, Bowden M, Leong H, Podor TJ, Gleave M, Sorensen PH. Martin MJ, et al. Mol Cell Biol. 2006 Mar;26(5):1754-69. doi: 10.1128/MCB.26.5.1754-1769.2006. Mol Cell Biol. 2006. PMID: 16478996 Free PMC article.

Insulin receptor isoform A and insulin-like growth factor II as additional treatment targets in human osteosarcoma.

Avnet S, Sciacca L, Salerno M, Gancitano G, Cassarino MF, Longhi A, Zakikhani M, Carboni JM, Gottardis M, Giunti A, Pollak M, Vigneri R, Baldini N. Avnet S, et al. Cancer Res. 2009 Mar 15;69(6):2443-52. doi: 10.1158/0008-5472.CAN-08-2645. Epub 2009 Mar 3. Cancer Res. 2009. PMID: 19258511

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