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Items: 1 to 20 of 173

1.

Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatin.

Xouri G, Squire A, Dimaki M, Geverts B, Verveer PJ, Taraviras S, Nishitani H, Houtsmuller AB, Bastiaens PI, Lygerou Z.

EMBO J. 2007 Mar 7;26(5):1303-14. Epub 2007 Feb 22.

2.

Proteolysis of DNA replication licensing factor Cdt1 in S-phase is performed independently of geminin through its N-terminal region.

Nishitani H, Lygerou Z, Nishimoto T.

J Biol Chem. 2004 Jul 16;279(29):30807-16. Epub 2004 May 11.

3.

Cdt1 interactions in the licensing process: a model for dynamic spatiotemporal control of licensing.

Xouri G, Dimaki M, Bastiaens PI, Lygerou Z.

Cell Cycle. 2007 Jul 1;6(13):1549-52. Epub 2007 May 22. Review.

PMID:
17598984
4.

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1.

Wohlschlegel JA, Dwyer BT, Dhar SK, Cvetic C, Walter JC, Dutta A.

Science. 2000 Dec 22;290(5500):2309-12.

5.

The replicative regulator protein geminin on chromatin in the HeLa cell cycle.

Kulartz M, Knippers R.

J Biol Chem. 2004 Oct 1;279(40):41686-94. Epub 2004 Jul 28.

6.

A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus.

Lutzmann M, Maiorano D, Méchali M.

EMBO J. 2006 Dec 13;25(24):5764-74. Epub 2006 Nov 23.

7.
8.

Cell cycle-dependent subcellular translocation of the human DNA licensing inhibitor geminin.

Dimaki M, Xouri G, Symeonidou IE, Sirinian C, Nishitani H, Taraviras S, Lygerou Z.

J Biol Chem. 2013 Aug 16;288(33):23953-63. doi: 10.1074/jbc.M113.453092. Epub 2013 Jun 29.

9.

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding.

Sugimoto N, Tatsumi Y, Tsurumi T, Matsukage A, Kiyono T, Nishitani H, Fujita M.

J Biol Chem. 2004 May 7;279(19):19691-7. Epub 2004 Mar 1.

10.

Cell cycle regulation of the licensing activity of Cdt1 in Xenopus laevis.

Maiorano D, Rul W, Méchali M.

Exp Cell Res. 2004 Apr 15;295(1):138-49.

PMID:
15051497
11.

Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint.

Higa LA, Mihaylov IS, Banks DP, Zheng J, Zhang H.

Nat Cell Biol. 2003 Nov;5(11):1008-15. Epub 2003 Oct 26. Erratum in: Nat Cell Biol. 2003 Dec;5(12):1122.

PMID:
14578910
12.

Geminin-Cdt1 balance is critical for genetic stability.

Saxena S, Dutta A.

Mutat Res. 2005 Jan 6;569(1-2):111-21. Review.

PMID:
15603756
13.

Control of DNA replication licensing in a cell cycle.

Nishitani H, Lygerou Z.

Genes Cells. 2002 Jun;7(6):523-34. Review.

14.

Geminin is bound to chromatin in G2/M phase to promote proper cytokinesis.

Nakuci E, Xu M, Pujana MA, Valls J, Elshamy WM.

Int J Biochem Cell Biol. 2006;38(7):1207-20. Epub 2006 Feb 3.

PMID:
16487741
15.
16.

Mouse geminin inhibits not only Cdt1-MCM6 interactions but also a novel intrinsic Cdt1 DNA binding activity.

Yanagi K, Mizuno T, You Z, Hanaoka F.

J Biol Chem. 2002 Oct 25;277(43):40871-80. Epub 2002 Aug 20.

17.

Cell cycle. License withheld--geminin blocks DNA replication.

Lygerou Z, Nurse P.

Science. 2000 Dec 22;290(5500):2271-3.

PMID:
11188727
18.

Dynamic association of ORCA with prereplicative complex components regulates DNA replication initiation.

Shen Z, Chakraborty A, Jain A, Giri S, Ha T, Prasanth KV, Prasanth SG.

Mol Cell Biol. 2012 Aug;32(15):3107-20. doi: 10.1128/MCB.00362-12. Epub 2012 May 29.

20.

The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions.

Luo L, Yang X, Takihara Y, Knoetgen H, Kessel M.

Nature. 2004 Feb 19;427(6976):749-53.

PMID:
14973489

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