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Items: 1 to 20 of 144

1.

[Iminosugars: current and future therapeutic applications].

Martin O.

Ann Pharm Fr. 2007 Jan;65(1):5-13. Review. French.

PMID:
17299348
2.

Iminosugars as therapeutic agents: recent advances and promising trends.

Nash RJ, Kato A, Yu CY, Fleet GW.

Future Med Chem. 2011 Sep;3(12):1513-21. doi: 10.4155/fmc.11.117. Review.

PMID:
21882944
3.

Gem-diamine 1-N-iminosugars as versatile glycomimetics: synthesis, biological activity and therapeutic potential.

Nishimura Y.

J Antibiot (Tokyo). 2009 Aug;62(8):407-23. doi: 10.1038/ja.2009.53. Epub 2009 Jul 3.

PMID:
19575039
4.

Therapeutic applications of iminosugars: current perspectives and future opportunities.

Horne G, Wilson FX.

Prog Med Chem. 2011;50:135-76. doi: 10.1016/B978-0-12-381290-2.00004-5. No abstract available.

PMID:
21315930
5.

Glycomimetics at the mirror: medicinal chemistry of L-iminosugars.

D'Alonzo D, Guaragna A, Palumbo G.

Curr Med Chem. 2009;16(4):473-505. Review.

PMID:
19199917
6.

Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses.

Butters TD, Dwek RA, Platt FM.

Glycobiology. 2005 Oct;15(10):43R-52R. Epub 2005 May 18. Review.

PMID:
15901676
7.

Combinatorial approaches to iminosugars as glycosidase and glycosyltransferase inhibitors.

Cipolla L, La Ferla B, Gregori M.

Comb Chem High Throughput Screen. 2006 Sep;9(8):571-82. Review.

PMID:
17017877
8.

Chaperone activity of bicyclic nojirimycin analogues for Gaucher mutations in comparison with N-(n-nonyl)deoxynojirimycin.

Luan Z, Higaki K, Aguilar-Moncayo M, Ninomiya H, Ohno K, García-Moreno MI, Ortiz Mellet C, García Fernández JM, Suzuki Y.

Chembiochem. 2009 Nov 23;10(17):2780-92. doi: 10.1002/cbic.200900442.

PMID:
19830760
9.

Inhibitors against glycosidases as medicines.

Kajimoto T, Node M.

Curr Top Med Chem. 2009;9(1):13-33. Review.

PMID:
19199994
10.
11.

Glycosidase inhibitors: update and perspectives on practical use.

Asano N.

Glycobiology. 2003 Oct;13(10):93R-104R. Epub 2003 Jul 8. Review.

PMID:
12851286
12.

α-Geminal dihydroxymethyl piperidine and pyrrolidine iminosugars: synthesis, conformational analysis, glycosidase inhibitory activity, and molecular docking studies.

Pawar NJ, Parihar VS, Chavan ST, Joshi R, Joshi PV, Sabharwal SG, Puranik VG, Dhavale DD.

J Org Chem. 2012 Sep 21;77(18):7873-82. Epub 2012 Aug 29.

PMID:
22873702
13.

Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments.

Somsák L, Nagya V, Hadady Z, Docsa T, Gergely P.

Curr Pharm Des. 2003;9(15):1177-89. Review.

PMID:
12769745
14.

Synthesis and biological evaluation of guanidine-type iminosugars.

Aguilar M, Díaz-Pérez P, García-Moreno MI, Mellet CO, García Fernandez JM.

J Org Chem. 2008 Mar 7;73(5):1995-8. doi: 10.1021/jo702374f. Epub 2008 Jan 24.

PMID:
18215064
15.

Azetidine- and N-carboxylic azetidine-iminosugars as amyloglucosidase inhibitors: synthesis, glycosidase inhibitory activity and molecular docking studies.

Gavale KS, Chavan SR, Khan A, Joshi R, Dhavale DD.

Org Biomol Chem. 2015 Jun 21;13(23):6634-46. doi: 10.1039/c5ob00668f. Epub 2015 May 20.

PMID:
25990982
16.

A prospect for pyrrolidine iminosugars as antidiabetic α-glucosidase inhibitors.

Trapero A, Llebaria A.

J Med Chem. 2012 Dec 13;55(23):10345-6. doi: 10.1021/jm301682r. Epub 2012 Nov 28. No abstract available.

PMID:
23190343
17.

α-1-C-butyl-1,4-dideoxy-1,4-imino-l-arabinitol as a second-generation iminosugar-based oral α-glucosidase inhibitor for improving postprandial hyperglycemia.

Kato A, Hayashi E, Miyauchi S, Adachi I, Imahori T, Natori Y, Yoshimura Y, Nash RJ, Shimaoka H, Nakagome I, Koseki J, Hirono S, Takahata H.

J Med Chem. 2012 Dec 13;55(23):10347-62. doi: 10.1021/jm301304e. Epub 2012 Nov 19.

PMID:
23106358
18.

Cyclodextrin-based iminosugar click clusters: the first examples of multivalent pharmacological chaperones for the treatment of lysosomal storage disorders.

Decroocq C, Rodríguez-Lucena D, Ikeda K, Asano N, Compain P.

Chembiochem. 2012 Mar 19;13(5):661-4. doi: 10.1002/cbic.201200005. Epub 2012 Feb 16. No abstract available.

PMID:
22344719
19.

Synthesis, computational study and glycosidase inhibitory activity of polyhydroxylated conidine alkaloids--a bicyclic iminosugar.

Sanap SP, Ghosh S, Jabgunde AM, Pinjari RV, Gejji SP, Singh S, Chopade BA, Dhavale DD.

Org Biomol Chem. 2010 Jul 21;8(14):3307-15. doi: 10.1039/c004690f. Epub 2010 Jun 2.

PMID:
20517582
20.

Natural and synthetic iminosugars as carbohydrate processing enzyme inhibitors for cancer therapy.

Wrodnigg TM, Steiner AJ, Ueberbacher BJ.

Anticancer Agents Med Chem. 2008 Jan;8(1):77-85. Review.

PMID:
18220507

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