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Items: 1 to 20 of 279

1.

Alpha-lipoic acid as a directly binding activator of the insulin receptor: protection from hepatocyte apoptosis.

Diesel B, Kulhanek-Heinze S, Höltje M, Brandt B, Höltje HD, Vollmar AM, Kiemer AK.

Biochemistry. 2007 Feb 27;46(8):2146-55. Epub 2007 Feb 3.

PMID:
17274632
2.

Phase II enzyme induction by alpha-lipoic acid through phosphatidylinositol 3-kinase-dependent C/EBPs activation.

Ki SH, Kim SG.

Xenobiotica. 2008 Jun;38(6):587-604. doi: 10.1080/00498250802126920 .

PMID:
18570160
3.

Carbon monoxide activates NF-kappaB via ROS generation and Akt pathways to protect against cell death of hepatocytes.

Kim HS, Loughran PA, Rao J, Billiar TR, Zuckerbraun BS.

Am J Physiol Gastrointest Liver Physiol. 2008 Jul;295(1):G146-G152. doi: 10.1152/ajpgi.00105.2007. Epub 2008 May 22.

4.

Alpha-lipoic acid decreases thiol reactivity of the insulin receptor and protein tyrosine phosphatase 1B in 3T3-L1 adipocytes.

Cho KJ, Moini H, Shon HK, Chung AS, Packer L.

Biochem Pharmacol. 2003 Sep 1;66(5):849-58.

PMID:
12948866
5.

Dose-related cytoprotective effect of alpha-lipoic acid on hydrogen peroxide-induced oxidative stress to pancreatic beta cells.

Lee BW, Kwon SJ, Chae HY, Kang JG, Kim CS, Lee SJ, Yoo HJ, Kim JH, Park KS, Ihm SH.

Free Radic Res. 2009 Jan;43(1):68-77. doi: 10.1080/10715760802590400.

PMID:
19358002
6.

Tumor necrosis factor (TNF) receptor-2-mediated DNA synthesis and proliferation in primary cultures of adult rat hepatocytes: The involvement of endogenous transforming growth factor-alpha.

Okamoto H, Kimura M, Watanabe N, Ogihara M.

Eur J Pharmacol. 2009 Feb 14;604(1-3):12-9. doi: 10.1016/j.ejphar.2008.12.004. Epub 2008 Dec 9.

PMID:
19100731
7.

Inflammation and apoptosis in aortic tissues of aged type II diabetes: amelioration with alpha-lipoic acid through phosphatidylinositol 3-kinase/Akt- dependent mechanism.

Bitar MS, Ayed AK, Abdel-Halim SM, Isenovic ER, Al-Mulla F.

Life Sci. 2010 Jun 5;86(23-24):844-53. doi: 10.1016/j.lfs.2010.03.019. Epub 2010 Apr 11.

PMID:
20388520
8.

Taurolithocholic acid-3 sulfate impairs insulin signaling in cultured rat hepatocytes and perfused rat liver.

Mannack G, Graf D, Donner MM, Richter L, Gorg B, Vom Dahl S, Haussinger D, Schliess F.

Cell Physiol Biochem. 2008;21(1-3):137-50. doi: 10.1159/000113756. Epub 2008 Jan 16.

9.

The natural antioxidant alpha-lipoic acid induces p27(Kip1)-dependent cell cycle arrest and apoptosis in MCF-7 human breast cancer cells.

Dozio E, Ruscica M, Passafaro L, Dogliotti G, Steffani L, Marthyn P, Pagani A, Demartini G, Esposti D, Fraschini F, Magni P.

Eur J Pharmacol. 2010 Sep 1;641(1):29-34. doi: 10.1016/j.ejphar.2010.05.009. Epub 2010 May 24. Erratum in: Eur J Pharmacol. 2011 Jan 10;650(1):486. Marthyn, Paola [added].

PMID:
20580704
10.

Tumor necrosis factor-alpha directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling.

Qin B, Anderson RA, Adeli K.

Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1120-9. doi: 10.1152/ajpgi.00407.2007. Epub 2008 Mar 27.

11.

delta-Opioid receptor-stimulated Akt signaling in neuroblastoma x glioma (NG108-15) hybrid cells involves receptor tyrosine kinase-mediated PI3K activation.

Heiss A, Ammer H, Eisinger DA.

Exp Cell Res. 2009 Jul 15;315(12):2115-25. doi: 10.1016/j.yexcr.2009.04.002. Epub 2009 Apr 10.

PMID:
19362548
12.

The active metabolite of leflunomide, A77 1726, protects rat hepatocytes against bile acid-induced apoptosis.

Vrenken TE, Buist-Homan M, Kalsbeek AJ, Faber KN, Moshage H.

J Hepatol. 2008 Nov;49(5):799-809. doi: 10.1016/j.jhep.2008.07.019. Epub 2008 Aug 22.

PMID:
18809221
13.
14.
15.

Effect of the antioxidant alpha-lipoic acid on apoptosis in human umbilical vein endothelial cells induced by high glucose.

Meng X, Li ZM, Zhou YJ, Cao YL, Zhang J.

Clin Exp Med. 2008 Mar;8(1):43-9. doi: 10.1007/s10238-008-0155-1. Epub 2008 Apr 3.

PMID:
18385940
16.

Antiapoptotic effect of c-Jun N-terminal Kinase-1 through Mcl-1 stabilization in TNF-induced hepatocyte apoptosis.

Kodama Y, Taura K, Miura K, Schnabl B, Osawa Y, Brenner DA.

Gastroenterology. 2009 Apr;136(4):1423-34. doi: 10.1053/j.gastro.2008.12.064. Epub 2009 Jan 6.

PMID:
19249395
17.

Pregnane X receptor activation protects rat hepatocytes against deoxycholic acid-induced apoptosis.

Zucchini-Pascal N, de Sousa G, Pizzol J, Rahmani R.

Liver Int. 2010 Feb;30(2):284-97. doi: 10.1111/j.1478-3231.2009.02108.x. Epub 2009 Sep 8.

PMID:
19737350
18.
19.

[Effect of alpha-lipoic acid on the apoptosis of PC12 cells induced by 6-hydroxydopamine].

Yuan CG, He L, Xue XL, Shi YT, Bi XH.

Shi Yan Sheng Wu Xue Bao. 2001 Mar;34(1):65-70. Chinese.

PMID:
12549012

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