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Items: 1 to 20 of 64

1.

Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer.

Kohonen-Corish MR, Sigglekow ND, Susanto J, Chapuis PH, Bokey EL, Dent OF, Chan C, Lin BP, Seng TJ, Laird PW, Young J, Leggett BA, Jass JR, Sutherland RL.

Oncogene. 2007 Jun 28;26(30):4435-41. Epub 2007 Jan 29.

PMID:
17260021
2.

The case for a genetic predisposition to serrated neoplasia in the colorectum: hypothesis and review of the literature.

Young J, Jass JR.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1778-84. Review.

3.

Distinct CpG island methylation profiles and BRAF mutation status in serrated and adenomatous colorectal polyps.

Kim YH, Kakar S, Cun L, Deng G, Kim YS.

Int J Cancer. 2008 Dec 1;123(11):2587-93. doi: 10.1002/ijc.23840.

4.

Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups.

Bond CE, Bettington ML, Pearson SA, McKeone DM, Leggett BA, Whitehall VL.

BMC Cancer. 2015 Jan 23;15:20. doi: 10.1186/s12885-015-1011-9.

5.

High frequency of genes' promoter methylation, but lack of BRAF V600E mutation among Iranian colorectal cancer patients.

Naghibalhossaini F, Hosseini HM, Mokarram P, Zamani M.

Pathol Oncol Res. 2011 Dec;17(4):819-25. doi: 10.1007/s12253-011-9388-5. Epub 2011 Apr 1.

PMID:
21455633
6.

BRAF, KRAS and PIK3CA mutations in colorectal serrated polyps and cancer: primary or secondary genetic events in colorectal carcinogenesis?

Velho S, Moutinho C, Cirnes L, Albuquerque C, Hamelin R, Schmitt F, Carneiro F, Oliveira C, Seruca R.

BMC Cancer. 2008 Sep 9;8:255. doi: 10.1186/1471-2407-8-255.

7.

BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum.

Kambara T, Simms LA, Whitehall VL, Spring KJ, Wynter CV, Walsh MD, Barker MA, Arnold S, McGivern A, Matsubara N, Tanaka N, Higuchi T, Young J, Jass JR, Leggett BA.

Gut. 2004 Aug;53(8):1137-44.

8.

Up and downregulation of p16(Ink4a) expression in BRAF-mutated polyps/adenomas indicates a senescence barrier in the serrated route to colon cancer.

Kriegl L, Neumann J, Vieth M, Greten FR, Reu S, Jung A, Kirchner T.

Mod Pathol. 2011 Jul;24(7):1015-22. doi: 10.1038/modpathol.2011.43. Epub 2011 Mar 18.

9.

Mutated in colorectal cancer, a putative tumor suppressor for serrated colorectal cancer, selectively represses beta-catenin-dependent transcription.

Fukuyama R, Niculaita R, Ng KP, Obusez E, Sanchez J, Kalady M, Aung PP, Casey G, Sizemore N.

Oncogene. 2008 Oct 9;27(46):6044-55. doi: 10.1038/onc.2008.204. Epub 2008 Jun 30.

10.

KRAS, BRAF oncogene mutations and tissue specific promoter hypermethylation of tumor suppressor SFRP2, DAPK1, MGMT, HIC1 and p16 genes in colorectal cancer patients.

Bagci B, Sari M, Karadayi K, Turan M, Ozdemir O, Bagci G.

Cancer Biomark. 2016 Jun 24;17(2):133-43. doi: 10.3233/CBM-160624.

PMID:
27540971
11.

MicroRNA-31 expression in relation to BRAF mutation, CpG island methylation and colorectal continuum in serrated lesions.

Ito M, Mitsuhashi K, Igarashi H, Nosho K, Naito T, Yoshii S, Takahashi H, Fujita M, Sukawa Y, Yamamoto E, Takahashi T, Adachi Y, Nojima M, Sasaki Y, Tokino T, Baba Y, Maruyama R, Suzuki H, Imai K, Yamamoto H, Shinomura Y.

Int J Cancer. 2014 Dec 1;135(11):2507-15. doi: 10.1002/ijc.28920. Epub 2014 Apr 30.

12.

Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.

Xu XL, Yu J, Zhang HY, Sun MH, Gu J, Du X, Shi DR, Wang P, Yang ZH, Zhu JD.

World J Gastroenterol. 2004 Dec 1;10(23):3441-54.

13.

Analysis of the association between CIMP and BRAF in colorectal cancer by DNA methylation profiling.

Hinoue T, Weisenberger DJ, Pan F, Campan M, Kim M, Young J, Whitehall VL, Leggett BA, Laird PW.

PLoS One. 2009 Dec 21;4(12):e8357. doi: 10.1371/journal.pone.0008357.

14.

Molecular characteristics of colorectal serrated polyps and hyperplastic polyps: A STROBE compliant article.

Sambuudash O, Kim HM, Jo H, Kim HS, Lee KJ, Park HJ, Kim JW, Cho MY, Kim HS.

Medicine (Baltimore). 2016 Dec;95(49):e5592.

15.

The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential.

Renaud F, Mariette C, Vincent A, Wacrenier A, Maunoury V, Leclerc J, Coppin L, Crépin M, Van Seuningen I, Leteurtre E, Buisine MP.

Int J Cancer. 2016 Mar 15;138(6):1472-81. doi: 10.1002/ijc.29891. Epub 2015 Oct 30.

16.

Genomic aberrations occurring in subsets of serrated colorectal lesions but not conventional adenomas.

Burnett-Hartman AN, Newcomb PA, Potter JD, Passarelli MN, Phipps AI, Wurscher MA, Grady WM, Zhu LC, Upton MP, Makar KW.

Cancer Res. 2013 May 1;73(9):2863-72. doi: 10.1158/0008-5472.CAN-12-3462. Epub 2013 Mar 28.

17.

The CpG island methylator phenotype and chromosomal instability are inversely correlated in sporadic colorectal cancer.

Goel A, Nagasaka T, Arnold CN, Inoue T, Hamilton C, Niedzwiecki D, Compton C, Mayer RJ, Goldberg R, Bertagnolli MM, Boland CR.

Gastroenterology. 2007 Jan;132(1):127-38. Epub 2006 Sep 20.

PMID:
17087942
18.

Loss of heterozygosity of the Mutated in Colorectal Cancer gene is not associated with promoter methylation in non-small cell lung cancer.

Poursoltan P, Currey N, Pangon L, van Kralingen C, Selinger CI, Mahar A, Cooper WA, Kennedy CW, McCaughan BC, Trent R, Kohonen-Corish MR.

Lung Cancer. 2012 Aug;77(2):272-6. doi: 10.1016/j.lungcan.2012.04.001. Epub 2012 Apr 26.

PMID:
22542170
19.

The CpG island methylator phenotype correlates with long-range epigenetic silencing in colorectal cancer.

Karpinski P, Ramsey D, Grzebieniak Z, Sasiadek MM, Blin N.

Mol Cancer Res. 2008 Apr;6(4):585-91. doi: 10.1158/1541-7786.MCR-07-2158.

20.

Promoter hypermethylation of tumor-related genes in the progression of colorectal neoplasia.

Bai AH, Tong JH, To KF, Chan MW, Man EP, Lo KW, Lee JF, Sung JJ, Leung WK.

Int J Cancer. 2004 Dec 10;112(5):846-53.

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