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Characterization of CD44v3-containing isoforms in head and neck cancer.

Reategui EP, de Mayolo AA, Das PM, Astor FC, Singal R, Hamilton KL, Goodwin WJ, Carraway KL, Franzmann EJ.

Cancer Biol Ther. 2006 Sep;5(9):1163-8. Epub 2006 Sep 11.


CD44 variant isoforms in head and neck squamous cell carcinoma progression.

Wang SJ, Wong G, de Heer AM, Xia W, Bourguignon LY.

Laryngoscope. 2009 Aug;119(8):1518-30. doi: 10.1002/lary.20506.


Potential stem cell marker CD44 is constitutively expressed in permanent cell lines of head and neck cancer.

Pries R, Witrkopf N, Trenkle T, Nitsch SM, Wollenberg B.

In Vivo. 2008 Jan-Feb;22(1):89-92.


Expression of antisense CD44 variant 6 inhibits colorectal tumor metastasis and tumor growth in a wound environment.

Reeder JA, Gotley DC, Walsh MD, Fawcett J, Antalis TM.

Cancer Res. 1998 Aug 15;58(16):3719-26.


DeltaNp63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck.

Boldrup L, Coates PJ, Gu X, Nylander K.

J Pathol. 2007 Dec;213(4):384-91.


Decreased levels of CD44 protein and mRNA in prostate carcinoma. Correlation with tumor grade and ploidy.

Kallakury BV, Yang F, Figge J, Smith KE, Kausik SJ, Tacy NJ, Fisher HA, Kaufman R, Figge H, Ross JS.

Cancer. 1996 Oct 1;78(7):1461-9.


Differential gene expression signature between primary and metastatic head and neck squamous cell carcinoma.

Liu CJ, Liu TY, Kuo LT, Cheng HW, Chu TH, Chang KW, Lin SC.

J Pathol. 2008 Mar;214(4):489-97. doi: 10.1002/path.2306.


Regulation of CD44v6-containing isoforms during proliferation of normal and malignant epithelial cells.

Soukka T, Salmi M, Joensuu H, Häkkinen L, Sointu P, Koulu L, Kalimo K, Klemi P, Grénman R, Jalkanen S.

Cancer Res. 1997 Jun 1;57(11):2281-9.


Inhibition of head and neck squamous cell carcinoma growth and invasion by the calcium influx inhibitor carboxyamido-triazole.

Wu Y, Palad AJ, Wasilenko WJ, Blackmore PF, Pincus WA, Schechter GL, Spoonster JR, Kohn EC, Somers KD.

Clin Cancer Res. 1997 Nov;3(11):1915-21.


Enhanced production of matrix metalloproteinase-2 in human head and neck carcinomas is correlated with lymph node metastasis.

Kawata R, Shimada T, Maruyama S, Hisa Y, Takenaka H, Murakami Y.

Acta Otolaryngol. 2002 Jan;122(1):101-6.


The association between elevated EphB4 expression, smoking status, and advanced-stage disease in patients with head and neck squamous cell carcinoma.

Sinha UK, Mazhar K, Chinn SB, Dhillon VK, Liu L, Masood R, Rice DH, Gill PS.

Arch Otolaryngol Head Neck Surg. 2006 Oct;132(10):1053-9.


Intratumoral lymphatics are essential for the metastatic spread and prognosis in squamous cell carcinomas of the head and neck region.

Maula SM, Luukkaa M, Grénman R, Jackson D, Jalkanen S, Ristamäki R.

Cancer Res. 2003 Apr 15;63(8):1920-6.


Nuclear translocations of beta-catenin and TCF4 in gastric cancers correlate with lymph node metastasis but probably not with CD44 expression.

Chen XY, Wang ZC, Li H, Cheng XX, Sun Y, Wang XW, Wu ML, Liu J.

Hum Pathol. 2005 Dec;36(12):1294-301. Epub 2005 Oct 28.


Expression profiles and clinical correlations of degradome components in the tumor microenvironment of head and neck squamous cell carcinoma.

Stokes A, Joutsa J, Ala-Aho R, Pitchers M, Pennington CJ, Martin C, Premachandra DJ, Okada Y, Peltonen J, Grénman R, James HA, Edwards DR, Kähäri VM.

Clin Cancer Res. 2010 Apr 1;16(7):2022-35. doi: 10.1158/1078-0432.CCR-09-2525. Epub 2010 Mar 21.


CD44v(3,8-10) is involved in cytoskeleton-mediated tumor cell migration and matrix metalloproteinase (MMP-9) association in metastatic breast cancer cells.

Bourguignon LY, Gunja-Smith Z, Iida N, Zhu HB, Young LJ, Muller WJ, Cardiff RD.

J Cell Physiol. 1998 Jul;176(1):206-15.


Metaanalysis of the significance of matrix metalloproteinases for lymph node disease in patients with head and neck squamous cell carcinoma.

Wiegand S, Dünne AA, Müller HH, Mandic R, Barth P, Davis RK, Werner JA.

Cancer. 2005 Jul 1;104(1):94-100.


CD44 variant isoforms promote metastasis formation by a tumor cell-matrix cross-talk that supports adhesion and apoptosis resistance.

Klingbeil P, Marhaba R, Jung T, Kirmse R, Ludwig T, Zöller M.

Mol Cancer Res. 2009 Feb;7(2):168-79. doi: 10.1158/1541-7786.MCR-08-0207. Epub 2009 Feb 10.


Role of hyaluronan synthase 2 to promote CD44-dependent oral cavity squamous cell carcinoma progression.

Wang SJ, Earle C, Wong G, Bourguignon LY.

Head Neck. 2013 Apr;35(4):511-20. doi: 10.1002/hed.22991. Epub 2012 Mar 31.


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