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Ab and T cell epitopes of influenza A virus, knowledge and opportunities.

Bui HH, Peters B, Assarsson E, Mbawuike I, Sette A.

Proc Natl Acad Sci U S A. 2007 Jan 2;104(1):246-51.


Evolutionarily conserved protein sequences of influenza a viruses, avian and human, as vaccine targets.

Heiny AT, Miotto O, Srinivasan KN, Khan AM, Zhang GL, Brusic V, Tan TW, August JT.

PLoS One. 2007 Nov 21;2(11):e1190.


MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response.

Testa JS, Shetty V, Hafner J, Nickens Z, Kamal S, Sinnathamby G, Philip R.

PLoS One. 2012;7(11):e48484. doi: 10.1371/journal.pone.0048484. Epub 2012 Nov 7.


Large scale genome analysis shows that the epitopes for broadly cross-reactive antibodies are predominant in the pandemic 2009 influenza virus A H1N1 strain.

Lara-Ramírez EE, Segura-Cabrera A, Salazar MI, Rodríguez-Pérez MA, Guo X.

Viruses. 2013 Nov 19;5(11):2796-802. doi: 10.3390/v5112796.


Conservation of T cell epitopes between seasonal influenza viruses and the novel influenza A H7N9 virus.

Mao H, Yen HL, Liu Y, Lau YL, Malik Peiris JS, Tu W.

Virol Sin. 2014 Jun;29(3):170-5. doi: 10.1007/s12250-014-3473-3. Epub 2014 Jun 17.


Cross-recognition of avian H5N1 influenza virus by human cytotoxic T-lymphocyte populations directed to human influenza A virus.

Kreijtz JH, de Mutsert G, van Baalen CA, Fouchier RA, Osterhaus AD, Rimmelzwaan GF.

J Virol. 2008 Jun;82(11):5161-6. doi: 10.1128/JVI.02694-07. Epub 2008 Mar 19.


Cross-reactive human B cell and T cell epitopes between influenza A and B viruses.

Terajima M, Babon JA, Co MD, Ennis FA.

Virol J. 2013 Jul 26;10:244. doi: 10.1186/1743-422X-10-244. Review.


A monoclonal antibody recognizes a highly conserved neutralizing epitope on hemagglutinin of H6N1 avian influenza virus.

He JL, Hsieh MS, Juang RH, Wang CH.

Vet Microbiol. 2014 Dec 5;174(3-4):333-41. doi: 10.1016/j.vetmic.2014.10.008. Epub 2014 Oct 25.


Preexisting CD4+ T-cell immunity in human population to avian influenza H7N9 virus: whole proteome-wide immunoinformatics analyses.

Duvvuri VR, Duvvuri B, Alice C, Wu GE, Gubbay JB, Wu J.

PLoS One. 2014 Mar 7;9(3):e91273. doi: 10.1371/journal.pone.0091273. eCollection 2014.


Significant impact of sequence variations in the nucleoprotein on CD8 T cell-mediated cross-protection against influenza A virus infections.

Zhong W, Liu F, Dong L, Lu X, Hancock K, Reinherz EL, Katz JM, Sambhara S.

PLoS One. 2010 May 11;5(5):e10583. doi: 10.1371/journal.pone.0010583.


Differential processing and presentation of the H-2D(b)-restricted epitope from two different strains of influenza virus nucleoprotein.

Potter P, Tourdot S, Blanchard T, Smith GL, Gould KG.

J Gen Virol. 2001 May;82(Pt 5):1069-74.


Healthy human subjects have CD4+ T cells directed against H5N1 influenza virus.

Roti M, Yang J, Berger D, Huston L, James EA, Kwok WW.

J Immunol. 2008 Feb 1;180(3):1758-68.


Generation of monoclonal antibodies reactive against subtype specific conserved B-cell epitopes on haemagglutinin protein of influenza virus H5N1.

Fiebig P, Shehata AA, Liebert UG.

Virus Res. 2015 Mar 2;199:46-55. doi: 10.1016/j.virusres.2015.01.006. Epub 2015 Jan 17.


Cross-protective potential of a novel monoclonal antibody directed against antigenic site B of the hemagglutinin of influenza A viruses.

Yoshida R, Igarashi M, Ozaki H, Kishida N, Tomabechi D, Kida H, Ito K, Takada A.

PLoS Pathog. 2009 Mar;5(3):e1000350. doi: 10.1371/journal.ppat.1000350. Epub 2009 Mar 20.


Immunoinformatic comparison of T-cell epitopes contained in novel swine-origin influenza A (H1N1) virus with epitopes in 2008-2009 conventional influenza vaccine.

De Groot AS, Ardito M, McClaine EM, Moise L, Martin WD.

Vaccine. 2009 Sep 25;27(42):5740-7. doi: 10.1016/j.vaccine.2009.07.040. Epub 2009 Aug 4.


Applications for T-cell epitope queries and tools in the Immune Epitope Database and Analysis Resource.

Kim Y, Sette A, Peters B.

J Immunol Methods. 2011 Nov 30;374(1-2):62-9. doi: 10.1016/j.jim.2010.10.010. Epub 2010 Oct 31. Review.


Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes.

Tan LC, Mowat AG, Fazou C, Rostron T, Roskell H, Dunbar PR, Tournay C, Romagné F, Peyrat MA, Houssaint E, Bonneville M, Rickinson AB, McMichael AJ, Callan MF.

Arthritis Res. 2000;2(2):154-64. Epub 2000 Feb 7.


A novel peptide ELISA for universal detection of antibodies to human H5N1 influenza viruses.

Velumani S, Ho HT, He F, Musthaq S, Prabakaran M, Kwang J.

PLoS One. 2011;6(6):e20737. doi: 10.1371/journal.pone.0020737. Epub 2011 Jun 10.


An antibody against a novel and conserved epitope in the hemagglutinin 1 subunit neutralizes numerous H5N1 influenza viruses.

Oh HL, Akerström S, Shen S, Bereczky S, Karlberg H, Klingström J, Lal SK, Mirazimi A, Tan YJ.

J Virol. 2010 Aug;84(16):8275-86. doi: 10.1128/JVI.02593-09. Epub 2010 Jun 2.

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