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Items: 1 to 20 of 82


To die or not to die: a HAT trick.

Tyteca S, Legube G, Trouche D.

Mol Cell. 2006 Dec 28;24(6):807-8. Review.


The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3.

Love IM, Sekaric P, Shi D, Grossman SR, Androphy EJ.

Cell Cycle. 2012 Jul 1;11(13):2458-66. doi: 10.4161/cc.20864. Epub 2012 Jul 1.


MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation.

Jin Y, Zeng SX, Dai MS, Yang XJ, Lu H.

J Biol Chem. 2002 Aug 23;277(34):30838-43. Epub 2002 Jun 14.


MDM2 inhibits p300-mediated p53 acetylation and activation by forming a ternary complex with the two proteins.

Kobet E, Zeng X, Zhu Y, Keller D, Lu H.

Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12547-52.


Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2.

Linares LK, Kiernan R, Triboulet R, Chable-Bessia C, Latreille D, Cuvier O, Lacroix M, Le Cam L, Coux O, Benkirane M.

Nat Cell Biol. 2007 Mar;9(3):331-8. Epub 2007 Feb 11.


Acetylation of the p53 DNA-binding domain regulates apoptosis induction.

Sykes SM, Mellert HS, Holbert MA, Li K, Marmorstein R, Lane WS, McMahon SB.

Mol Cell. 2006 Dec 28;24(6):841-51.


The kinetics of p53-binding and histone acetylation at target promoters do not strictly correlate with gene expression after UV damage.

Magrini R, Russo D, Fronza G, Inga A, Menichini P.

J Cell Biochem. 2007 Apr 1;100(5):1276-87.


A new function for p53 ubiquitination.

Hirano Y, Ronai Z.

Cell. 2006 Nov 17;127(4):675-7.


Negative regulation of the acetyltransferase TIP60-p53 interplay by UHRF1 (ubiquitin-like with PHD and RING finger domains 1).

Dai C, Shi D, Gu W.

J Biol Chem. 2013 Jul 5;288(27):19581-92. doi: 10.1074/jbc.M113.476606. Epub 2013 May 15.


Defective p53 post-translational modification required for wild type p53 inactivation in malignant epithelial cells with mdm2 gene amplification.

Knights CD, Liu Y, Appella E, Kulesz-Martin M.

J Biol Chem. 2003 Dec 26;278(52):52890-900. Epub 2003 Oct 10.


Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases.

Barlev NA, Liu L, Chehab NH, Mansfield K, Harris KG, Halazonetis TD, Berger SL.

Mol Cell. 2001 Dec;8(6):1243-54.


MOZ increases p53 acetylation and premature senescence through its complex formation with PML.

Rokudai S, Laptenko O, Arnal SM, Taya Y, Kitabayashi I, Prives C.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3895-900. doi: 10.1073/pnas.1300490110. Epub 2013 Feb 19.


MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation.

Ito A, Kawaguchi Y, Lai CH, Kovacs JJ, Higashimoto Y, Appella E, Yao TP.

EMBO J. 2002 Nov 15;21(22):6236-45.


Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53.

Charvet C, Wissler M, Brauns-Schubert P, Wang SJ, Tang Y, Sigloch FC, Mellert H, Brandenburg M, Lindner SE, Breit B, Green DR, McMahon SB, Borner C, Gu W, Maurer U.

Mol Cell. 2011 Jun 10;42(5):584-96. doi: 10.1016/j.molcel.2011.03.033.


Nuclear interactor of ARF and Mdm2 regulates multiple pathways to activate p53.

Reed SM, Hagen J, Tompkins VS, Thies K, Quelle FW, Quelle DE.

Cell Cycle. 2014;13(8):1288-98. doi: 10.4161/cc.28202. Epub 2014 Feb 19.


HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage.

Di Stefano V, Soddu S, Sacchi A, D'Orazi G.

Oncogene. 2005 Aug 18;24(35):5431-42.


Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells.

Xu D, Wilson TJ, Chan D, De Luca E, Zhou J, Hertzog PJ, Kola I.

EMBO J. 2002 Aug 1;21(15):4081-93.


Acidic domain is indispensable for MDM2 to negatively regulate the acetylation of p53.

Wang Q, Yang Y, Wang L, Zhang PZ, Yu L.

Biochem Biophys Res Commun. 2008 Sep 26;374(3):437-41. doi: 10.1016/j.bbrc.2008.07.038. Epub 2008 Jul 16.


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