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Items: 1 to 20 of 162

1.

Siah-1 facilitates ubiquitination and degradation of factor inhibiting HIF-1alpha (FIH).

Fukuba H, Yamashita H, Nagano Y, Jin HG, Hiji M, Ohtsuki T, Takahashi T, Kohriyama T, Matsumoto M.

Biochem Biophys Res Commun. 2007 Feb 9;353(2):324-9. Epub 2006 Dec 14. Retraction in: Biochem Biophys Res Commun. 2009 Oct 23;388(3):618.

PMID:
17188242
2.

Abundance of aspargynyl-hydroxylase FIH is regulated by Siah-1 under normoxic conditions.

Fukuba H, Takahashi T, Jin HG, Kohriyama T, Matsumoto M.

Neurosci Lett. 2008 Mar 15;433(3):209-14. doi: 10.1016/j.neulet.2007.12.069. Epub 2008 Jan 20.

PMID:
18280659
3.
4.

Inhibition of Siah ubiquitin ligase function.

Möller A, House CM, Wong CS, Scanlon DB, Liu MC, Ronai Z, Bowtell DD.

Oncogene. 2009 Jan 15;28(2):289-96. doi: 10.1038/onc.2008.382. Epub 2008 Oct 13.

5.

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.

Koivunen P, Hirsilä M, Günzler V, Kivirikko KI, Myllyharju J.

J Biol Chem. 2004 Mar 12;279(11):9899-904. Epub 2003 Dec 29.

6.

Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha.

Shin DH, Li SH, Yang SW, Lee BL, Lee MK, Park JW.

FEBS J. 2009 Jul;276(13):3470-80. doi: 10.1111/j.1742-4658.2009.07069.x. Epub 2009 May 18.

7.

CITED2 mediates the paradoxical responses of HIF-1alpha to proteasome inhibition.

Shin DH, Li SH, Chun YS, Huang LE, Kim MS, Park JW.

Oncogene. 2008 Mar 20;27(13):1939-44. Epub 2007 Oct 1.

PMID:
17906695
8.

Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].

Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ.

J Biol Chem. 2004 Oct 8;279(41):42719-25. Epub 2004 Aug 9. Erratum in: J Biol Chem. 2004 Dec 24;279(52):54974.

9.

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family.

Hewitson KS, McNeill LA, Riordan MV, Tian YM, Bullock AN, Welford RW, Elkins JM, Oldham NJ, Bhattacharya S, Gleadle JM, Ratcliffe PJ, Pugh CW, Schofield CJ.

J Biol Chem. 2002 Jul 19;277(29):26351-5. Epub 2002 May 31.

10.

A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.

Nguyen LK, Cavadas MA, Scholz CC, Fitzpatrick SF, Bruning U, Cummins EP, Tambuwala MM, Manresa MC, Kholodenko BN, Taylor CT, Cheong A.

J Cell Sci. 2013 Mar 15;126(Pt 6):1454-63. doi: 10.1242/jcs.119974. Epub 2013 Feb 6. Erratum in: J Cell Sci. 2015 Jan 15;128(2):422.

11.

Siah: new players in the cellular response to hypoxia.

Nakayama K, Ronai Z.

Cell Cycle. 2004 Nov;3(11):1345-7. Epub 2004 Nov 6.

PMID:
15492505
12.

Phospholipase D2 promotes degradation of hypoxia-inducible factor-1α independent of lipase activity.

Park MH, Bae SS, Choi KY, Min do S.

Exp Mol Med. 2015 Nov 27;47:e196. doi: 10.1038/emm.2015.87.

13.

Activation of hypoxia-induced transcription in normoxia.

Hägg M, Wennström S.

Exp Cell Res. 2005 May 15;306(1):180-91. Epub 2005 Mar 19.

PMID:
15878343
14.

The zinc chelator, N,N,N',N'-tetrakis (2-pyridylmethyl) ethylenediamine, increases the level of nonfunctional HIF-1alpha protein in normoxic cells.

Choi SM, Choi KO, Lee N, Oh M, Park H.

Biochem Biophys Res Commun. 2006 May 19;343(4):1002-8. Epub 2006 Mar 20.

PMID:
16579968
15.
16.

Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor.

Linke S, Stojkoski C, Kewley RJ, Booker GW, Whitelaw ML, Peet DJ.

J Biol Chem. 2004 Apr 2;279(14):14391-7. Epub 2004 Jan 20.

17.
18.

Ankyrin Repeat Proteins of Orf Virus Influence the Cellular Hypoxia Response Pathway.

Chen DY, Fabrizio JA, Wilkins SE, Dave KA, Gorman JJ, Gleadle JM, Fleming SB, Peet DJ, Mercer AA.

J Virol. 2016 Dec 16;91(1). pii: e01430-16. Print 2017 Jan 1.

19.

Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.

Callapina M, Zhou J, Schnitzer S, Metzen E, Lohr C, Deitmer JW, Brüne B.

Exp Cell Res. 2005 May 15;306(1):274-84. Epub 2005 Mar 20.

PMID:
15878351

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