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Items: 1 to 20 of 94


Biological activity of designed photolabile metal nitrosyls: light-dependent activation of soluble guanylate cyclase and vasorelaxant properties in rat aorta.

Madhani M, Patra AK, Miller TW, Eroy-Reveles AA, Hobbs AJ, Fukuto JM, Mascharak PK.

J Med Chem. 2006 Dec 14;49(25):7325-30.


Soluble guanylyl cyclase activation by HMR-1766 (ataciguat) in cells exposed to oxidative stress.

Zhou Z, Pyriochou A, Kotanidou A, Dalkas G, van Eickels M, Spyroulias G, Roussos C, Papapetropoulos A.

Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1763-71. doi: 10.1152/ajpheart.51.2008. Epub 2008 Aug 29.


Tirofiban increases soluble guanylate cyclase in rat vascular walls: pharmacological and pathophysiological consequences.

Ruiz-Torres MP, Griera M, Chamorro A, Díez-Marqués ML, Rodríguez-Puyol D, Rodríguez-Puyol M.

Cardiovasc Res. 2009 Apr 1;82(1):125-32. doi: 10.1093/cvr/cvn359. Epub 2009 Jan 6.


Nitric oxide generated by the compound RuBPY promotes the vascular smooth cell membrane hyperpolarization.

Pereira AC, Lunardi CN, Paulo M, da Silva RS, Bendhack LM.

Eur J Pharm Sci. 2013 Mar 12;48(4-5):604-10. doi: 10.1016/j.ejps.2013.01.003. Epub 2013 Jan 17.


H2O2 regulation of vascular function through sGC mRNA stabilization by HuR.

Martín-Garrido A, González-Ramos M, Griera M, Guijarro B, Cannata-Andia J, Rodriguez-Puyol D, Rodriguez-Puyol M, Saura M.

Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):567-73. doi: 10.1161/ATVBAHA.110.219725. Epub 2010 Dec 16.


Soluble guanylate cyclase is required for systemic vasodilation but not positive inotropy induced by nitroxyl in the mouse.

Zhu G, Groneberg D, Sikka G, Hori D, Ranek MJ, Nakamura T, Takimoto E, Paolocci N, Berkowitz DE, Friebe A, Kass DA.

Hypertension. 2015 Feb;65(2):385-92. doi: 10.1161/HYPERTENSIONAHA.114.04285. Epub 2014 Dec 1.


Regulation of the expression of soluble guanylyl cyclase by reactive oxygen species.

Gerassimou C, Kotanidou A, Zhou Z, Simoes DC, Roussos C, Papapetropoulos A.

Br J Pharmacol. 2007 Apr;150(8):1084-91. Epub 2007 Mar 5. Erratum in: Br J Pharmacol. 2007 Apr;150(8):1092. Simoes, D D C [corrected to Simoes, D C M].


Functional role of the soluble guanylyl cyclase alpha(1) subunit in vascular smooth muscle relaxation.

Nimmegeers S, Sips P, Buys E, Brouckaert P, Van de Voorde J.

Cardiovasc Res. 2007 Oct 1;76(1):149-59. Epub 2007 Jun 12.


Phosphodiesterase 3A expression is modulated by nitric oxide in rat pulmonary artery smooth muscle cells.

Busch CJ, Graveline AR, Jiramongkolchai K, Liu H, Sanchez LS, Bloch KD.

J Physiol Pharmacol. 2010 Dec;61(6):663-9.


Nitric oxide attenuates endothelin-1-induced activation of ERK1/2, PKB, and Pyk2 in vascular smooth muscle cells by a cGMP-dependent pathway.

Bouallegue A, Daou GB, Srivastava AK.

Am J Physiol Heart Circ Physiol. 2007 Oct;293(4):H2072-9. Epub 2007 Jul 20.


Ruthenium-nitrite complex as pro-drug releases NO in a tissue and enzyme-dependent way.

Pereira Ade C, Ford PC, da Silva RS, Bendhack LM.

Nitric Oxide. 2011 May 31;24(4):192-8. doi: 10.1016/j.niox.2011.03.001. Epub 2011 Mar 31.


Investigation of the role of the NO-cGMP pathway on YC-1 and DEA/NO effects on thoracic aorta smooth muscle responses in a rat preeclampsia model.

Turgut NH, Temiz TK, Turgut B, Karadas B, Parlak M, Bagcivan I.

Can J Physiol Pharmacol. 2013 Oct;91(10):797-803. doi: 10.1139/cjpp-2013-0086. Epub 2013 May 23.


Vasorelaxation induced by the new nitric oxide donor cis-[Ru(Cl)(bpy)(2)(NO)](PF(6)) is due to activation of K(Ca) by a cGMP-dependent pathway.

Lunardi CN, Vercesi JA, da Silva RS, Bendhack LM.

Vascul Pharmacol. 2007 Aug-Sep;47(2-3):139-44. Epub 2007 Jun 2.


Effect of hypercholesterolemia on expression and function of vascular soluble guanylyl cyclase.

Laber U, Kober T, Schmitz V, Schrammel A, Meyer W, Mayer B, Weber M, Kojda G.

Circulation. 2002 Feb 19;105(7):855-60.


Chronic hypoxia attenuates cGMP-dependent pulmonary vasodilation.

Jernigan NL, Resta TC.

Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1366-75.


Altered vascular function in fetal programming of hypertension.

Lamireau D, Nuyt AM, Hou X, Bernier S, Beauchamp M, Gobeil F Jr, Lahaie I, Varma DR, Chemtob S.

Stroke. 2002 Dec;33(12):2992-8.


High-fat diet-induced obesity leads to increased NO sensitivity of rat coronary arterioles: role of soluble guanylate cyclase activation.

Jebelovszki E, Kiraly C, Erdei N, Feher A, Pasztor ET, Rutkai I, Forster T, Edes I, Koller A, Bagi Z.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2558-64. doi: 10.1152/ajpheart.01198.2007. Epub 2008 Apr 11.


Natriuretic peptides and nitric oxide stimulate cGMP synthesis in different cellular compartments.

Piggott LA, Hassell KA, Berkova Z, Morris AP, Silberbach M, Rich TC.

J Gen Physiol. 2006 Jul;128(1):3-14. Epub 2006 Jun 12.


Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule.

Foresti R, Hammad J, Clark JE, Johnson TR, Mann BE, Friebe A, Green CJ, Motterlini R.

Br J Pharmacol. 2004 Jun;142(3):453-60. Epub 2004 May 17.

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