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Items: 1 to 20 of 311

1.

Substrate binding and catalytic mechanism of human choline acetyltransferase.

Kim AR, Rylett RJ, Shilton BH.

Biochemistry. 2006 Dec 12;45(49):14621-31.

PMID:
17144655
2.

Structural insights and functional implications of choline acetyltransferase.

Govindasamy L, Pedersen B, Lian W, Kukar T, Gu Y, Jin S, Agbandje-McKenna M, Wu D, McKenna R.

J Struct Biol. 2004 Nov;148(2):226-35.

PMID:
15477102
3.

Crystallographic analysis of substrate binding and catalysis in dihydrolipoyl transacetylase (E2p).

Mattevi A, Obmolova G, Kalk KH, Teplyakov A, Hol WG.

Biochemistry. 1993 Apr 20;32(15):3887-901.

PMID:
8471601
4.

Redesign of cosubstrate specificity and identification of important residues for substrate binding to hChAT.

Green KD, Porter VR, Zhang Y, Garneau-Tsodikova S.

Biochemistry. 2010 Jul 27;49(29):6219-27. doi: 10.1021/bi1007996.

PMID:
20560540
5.

Surface-entropy reduction used in the crystallization of human choline acetyltransferase.

Kim AR, Dobransky T, Rylett RJ, Shilton BH.

Acta Crystallogr D Biol Crystallogr. 2005 Sep;61(Pt 9):1306-10. Epub 2005 Aug 16.

PMID:
16131766
6.

Two methods for large-scale purification of recombinant human choline acetyltransferase.

Kim AR, Doherty-Kirby A, Lajoie G, Rylett RJ, Shilton BH.

Protein Expr Purif. 2005 Mar;40(1):107-17.

PMID:
15721778
7.

Protein kinase C isoforms differentially phosphorylate human choline acetyltransferase regulating its catalytic activity.

Dobransky T, Doherty-Kirby A, Kim AR, Brewer D, Lajoie G, Rylett RJ.

J Biol Chem. 2004 Dec 10;279(50):52059-68. Epub 2004 Sep 20.

8.

Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function.

Haapalainen AM, Meriläinen G, Pirilä PL, Kondo N, Fukao T, Wierenga RK.

Biochemistry. 2007 Apr 10;46(14):4305-21. Epub 2007 Mar 20.

PMID:
17371050
9.

Crystallographic analysis of the reaction pathway of Zoogloea ramigera biosynthetic thiolase.

Modis Y, Wierenga RK.

J Mol Biol. 2000 Apr 14;297(5):1171-82.

PMID:
10764581
10.

A model for dynamic regulation of choline acetyltransferase by phosphorylation.

Dobransky T, Rylett RJ.

J Neurochem. 2005 Oct;95(2):305-13. Epub 2005 Aug 31. Review.

11.

Crystallization and preliminary X-ray crystallographic studies on recombinant rat choline acetyltransferase.

Lian W, Gu Y, Pedersen B, Kukar T, Govindasamy L, Agbandje-McKenna M, Jin S, McKenna R, Wu D.

Acta Crystallogr D Biol Crystallogr. 2004 Feb;60(Pt 2):374-5. Epub 2004 Jan 23.

PMID:
14747730
13.
14.

Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders.

Cai Y, Cronin CN, Engel AG, Ohno K, Hersh LB, Rodgers DW.

EMBO J. 2004 May 19;23(10):2047-58. Epub 2004 May 6.

15.

Functional characterization of phosphorylation of 69-kDa human choline acetyltransferase at serine 440 by protein kinase C.

Dobransky T, Davis WL, Rylett RJ.

J Biol Chem. 2001 Jun 22;276(25):22244-50. Epub 2001 Apr 12.

16.

The thiolase reaction mechanism: the importance of Asn316 and His348 for stabilizing the enolate intermediate of the Claisen condensation.

Meriläinen G, Poikela V, Kursula P, Wierenga RK.

Biochemistry. 2009 Nov 24;48(46):11011-25. doi: 10.1021/bi901069h.

PMID:
19842716
17.

Crystal structure of yeast acetyl-coenzyme A synthetase in complex with AMP.

Jogl G, Tong L.

Biochemistry. 2004 Feb 17;43(6):1425-31.

PMID:
14769018
18.

High resolution crystal structures of human cytosolic thiolase (CT): a comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I.

Kursula P, Sikkilä H, Fukao T, Kondo N, Wierenga RK.

J Mol Biol. 2005 Mar 18;347(1):189-201. Epub 2005 Jan 19.

PMID:
15733928
19.
20.

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