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Items: 1 to 20 of 119

1.

ESET/SETDB1 gene expression and histone H3 (K9) trimethylation in Huntington's disease.

Ryu H, Lee J, Hagerty SW, Soh BY, McAlpin SE, Cormier KA, Smith KM, Ferrante RJ.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19176-81. Epub 2006 Dec 1.

2.

Monoallele deletion of CBP leads to pericentromeric heterochromatin condensation through ESET expression and histone H3 (K9) methylation.

Lee J, Hagerty S, Cormier KA, Kim J, Kung AL, Ferrante RJ, Ryu H.

Hum Mol Genet. 2008 Jun 15;17(12):1774-82. doi: 10.1093/hmg/ddn067. Epub 2008 Mar 4.

3.

mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression.

Wang H, An W, Cao R, Xia L, Erdjument-Bromage H, Chatton B, Tempst P, Roeder RG, Zhang Y.

Mol Cell. 2003 Aug;12(2):475-87.

4.

Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease.

Ferrante RJ, Ryu H, Kubilus JK, D'Mello S, Sugars KL, Lee J, Lu P, Smith K, Browne S, Beal MF, Kristal BS, Stavrovskaya IG, Hewett S, Rubinsztein DC, Langley B, Ratan RR.

J Neurosci. 2004 Nov 17;24(46):10335-42.

5.

Histone H3-K9 methyltransferase ESET is essential for early development.

Dodge JE, Kang YK, Beppu H, Lei H, Li E.

Mol Cell Biol. 2004 Mar;24(6):2478-86.

7.

Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor.

Yang L, Xia L, Wu DY, Wang H, Chansky HA, Schubach WH, Hickstein DD, Zhang Y.

Oncogene. 2002 Jan 3;21(1):148-52.

8.

Modulation of nucleosome dynamics in Huntington's disease.

Stack EC, Del Signore SJ, Luthi-Carter R, Soh BY, Goldstein DR, Matson S, Goodrich S, Markey AL, Cormier K, Hagerty SW, Smith K, Ryu H, Ferrante RJ.

Hum Mol Genet. 2007 May 15;16(10):1164-75. Epub 2007 Apr 2.

PMID:
17403718
9.

Setdb1-mediated histone H3K9 hypermethylation in neurons worsens the neurological phenotype of Mecp2-deficient mice.

Jiang Y, Matevossian A, Guo Y, Akbarian S.

Neuropharmacology. 2011 Jun;60(7-8):1088-97. doi: 10.1016/j.neuropharm.2010.09.020. Epub 2010 Sep 30.

10.

A jumonji (Jarid2) protein complex represses cyclin D1 expression by methylation of histone H3-K9.

Shirato H, Ogawa S, Nakajima K, Inagawa M, Kojima M, Tachibana M, Shinkai Y, Takeuchi T.

J Biol Chem. 2009 Jan 9;284(2):733-9. doi: 10.1074/jbc.M804994200. Epub 2008 Nov 14.

11.

Genomic structure and expression of the mouse ESET gene encoding an ERG-associated histone methyltransferase with a SET domain.

Blackburn ML, Chansky HA, Zielinska-Kwiatkowska A, Matsui Y, Yang L.

Biochim Biophys Acta. 2003 Oct 1;1629(1-3):8-14.

PMID:
14522075
12.

An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B.

Yang L, Mei Q, Zielinska-Kwiatkowska A, Matsui Y, Blackburn ML, Benedetti D, Krumm AA, Taborsky GJ Jr, Chansky HA.

Biochem J. 2003 Feb 1;369(Pt 3):651-7.

13.

Setdb1 histone methyltransferase regulates mood-related behaviors and expression of the NMDA receptor subunit NR2B.

Jiang Y, Jakovcevski M, Bharadwaj R, Connor C, Schroeder FA, Lin CL, Straubhaar J, Martin G, Akbarian S.

J Neurosci. 2010 May 26;30(21):7152-67. doi: 10.1523/JNEUROSCI.1314-10.2010.

14.

The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells.

Li H, Rauch T, Chen ZX, Szabó PE, Riggs AD, Pfeifer GP.

J Biol Chem. 2006 Jul 14;281(28):19489-500. Epub 2006 May 8.

15.

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

Matsui T, Leung D, Miyashita H, Maksakova IA, Miyachi H, Kimura H, Tachibana M, Lorincz MC, Shinkai Y.

Nature. 2010 Apr 8;464(7290):927-31. doi: 10.1038/nature08858. Epub 2010 Feb 17. Erratum in: Nature. 2014 Sep 4;513(7516):128.

PMID:
20164836
16.

Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice.

Ferrante RJ, Kubilus JK, Lee J, Ryu H, Beesen A, Zucker B, Smith K, Kowall NW, Ratan RR, Luthi-Carter R, Hersch SM.

J Neurosci. 2003 Oct 15;23(28):9418-27.

17.

The histone methyltransferase ESET is required for the survival of spermatogonial stem/progenitor cells in mice.

An J, Zhang X, Qin J, Wan Y, Hu Y, Liu T, Li J, Dong W, Du E, Pan C, Zeng W.

Cell Death Dis. 2014 Apr 24;5:e1196. doi: 10.1038/cddis.2014.171.

18.

Specific promoter deacetylation of histone H3 is conserved across mouse models of Huntington's disease in the absence of bulk changes.

Guiretti D, Sempere A, Lopez-Atalaya JP, Ferrer-Montiel A, Barco A, Valor LM.

Neurobiol Dis. 2016 May;89:190-201. doi: 10.1016/j.nbd.2016.02.004. Epub 2016 Feb 3.

PMID:
26851501
19.

Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's disease.

Lee J, Hwang YJ, Kim Y, Lee MY, Hyeon SJ, Lee S, Kim DH, Jang SJ, Im H, Min SJ, Choo H, Pae AN, Kim DJ, Cho KS, Kowall NW, Ryu H.

Acta Neuropathol. 2017 Nov;134(5):729-748. doi: 10.1007/s00401-017-1732-8. Epub 2017 Jun 7.

PMID:
28593442
20.

Involvement of histone methylation and phosphorylation in regulation of transcription by thyroid hormone receptor.

Li J, Lin Q, Yoon HG, Huang ZQ, Strahl BD, Allis CD, Wong J.

Mol Cell Biol. 2002 Aug;22(16):5688-97.

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