Similar articles for PMID: 17141198

Year	Number of Results
1999	1
2002	1
2003	1
2005	6
2006	4
2007	17
2008	24
2009	10
2010	12
2011	5
2012	10
2013	9
2014	4
2015	5
2016	2
2017	9
2018	6
2019	3
2020	6
2021	2
2023	1
2024	0

1

Identification of a novel competitive inhibitor of p38alpha MAPK by a human PBMC screen.

Liu YC, Ko CC, Cheng FC, Huang PT, Lou KL, Chow LP. Liu YC, et al. Biochem Biophys Res Commun. 2007 Jan 19;352(3):656-61. doi: 10.1016/j.bbrc.2006.11.069. Epub 2006 Nov 27. Biochem Biophys Res Commun. 2007. PMID: 17141198

2

Concentration-dependent roles for heparin in modifying lipopolysaccharide-induced activation of mononuclear cells in whole blood.

Hochart H, Jenkins PV, Preston RJ, Smith OP, White B, O'Donnell J. Hochart H, et al. Thromb Haemost. 2008 Mar;99(3):570-5. doi: 10.1160/TH07-06-0424. Thromb Haemost. 2008. PMID: 18327406

3

Part 1: Structure-Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38alpha mitogen-activated protein kinase.

Wurz RP, Pettus LH, Xu S, Henkle B, Sherman L, Plant M, Miner K, McBride H, Wong LM, Saris CJ, Lee MR, Chmait S, Mohr C, Hsieh F, Tasker AS. Wurz RP, et al. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4724-8. doi: 10.1016/j.bmcl.2009.06.058. Epub 2009 Jun 17. Bioorg Med Chem Lett. 2009. PMID: 19574047

4

Design, synthesis, and anti-inflammatory properties of orally active 4-(phenylamino)-pyrrolo[2,1-f][1,2,4]triazine p38alpha mitogen-activated protein kinase inhibitors.

Hynes J Jr, Dyckman AJ, Lin S, Wrobleski ST, Wu H, Gillooly KM, Kanner SB, Lonial H, Loo D, McIntyre KW, Pitt S, Shen DR, Shuster DJ, Yang X, Zhang R, Behnia K, Zhang H, Marathe PH, Doweyko AM, Tokarski JS, Sack JS, Pokross M, Kiefer SE, Newitt JA, Barrish JC, Dodd J, Schieven GL, Leftheris K. Hynes J Jr, et al. J Med Chem. 2008 Jan 10;51(1):4-16. doi: 10.1021/jm7009414. Epub 2007 Dec 12. J Med Chem. 2008. PMID: 18072718

5

3-amino-7-phthalazinylbenzoisoxazoles as a novel class of potent, selective, and orally available inhibitors of p38alpha mitogen-activated protein kinase.

Pettus LH, Xu S, Cao GQ, Chakrabarti PP, Rzasa RM, Sham K, Wurz RP, Zhang D, Middleton S, Henkle B, Plant MH, Saris CJ, Sherman L, Wong LM, Powers DA, Tudor Y, Yu V, Lee MR, Syed R, Hsieh F, Tasker AS. Pettus LH, et al. J Med Chem. 2008 Oct 23;51(20):6280-92. doi: 10.1021/jm8005405. Epub 2008 Sep 26. J Med Chem. 2008. PMID: 18817364

6

p38alpha mitogen-activated protein kinase inhibitors: optimization of a series of biphenylamides to give a molecule suitable for clinical progression.

Aston NM, Bamborough P, Buckton JB, Edwards CD, Holmes DS, Jones KL, Patel VK, Smee PA, Somers DO, Vitulli G, Walker AL. Aston NM, et al. J Med Chem. 2009 Oct 22;52(20):6257-69. doi: 10.1021/jm9004779. J Med Chem. 2009. PMID: 19772287

7

Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases.

Kjellerup RB, Kragballe K, Iversen L, Johansen C. Kjellerup RB, et al. Exp Dermatol. 2008 Jun;17(6):498-504. doi: 10.1111/j.1600-0625.2007.00672.x. Epub 2007 Dec 13. Exp Dermatol. 2008. PMID: 18081851

8

Pamapimod, a novel p38 mitogen-activated protein kinase inhibitor: preclinical analysis of efficacy and selectivity.

Hill RJ, Dabbagh K, Phippard D, Li C, Suttmann RT, Welch M, Papp E, Song KW, Chang KC, Leaffer D, Kim YN, Roberts RT, Zabka TS, Aud D, Dal Porto J, Manning AM, Peng SL, Goldstein DM, Wong BR. Hill RJ, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):610-9. doi: 10.1124/jpet.108.139006. Epub 2008 Sep 5. J Pharmacol Exp Ther. 2008. PMID: 18776065

9

Benzothiazole based inhibitors of p38alpha MAP kinase.

Liu C, Lin J, Pitt S, Zhang RF, Sack JS, Kiefer SE, Kish K, Doweyko AM, Zhang H, Marathe PH, Trzaskos J, Mckinnon M, Dodd JH, Barrish JC, Schieven GL, Leftheris K. Liu C, et al. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1874-9. doi: 10.1016/j.bmcl.2008.02.011. Epub 2008 Feb 10. Bioorg Med Chem Lett. 2008. PMID: 18296051

10

The multicomponent phytopharmaceutical SKI306X inhibits in vitro cartilage degradation and the production of inflammatory mediators.

Hartog A, Hougee S, Faber J, Sanders A, Zuurman C, Smit HF, van der Kraan PM, Hoijer MA, Garssen J. Hartog A, et al. Phytomedicine. 2008 May;15(5):313-20. doi: 10.1016/j.phymed.2007.09.005. Epub 2007 Oct 18. Phytomedicine. 2008. PMID: 17949960

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