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Items: 1 to 20 of 128

1.

Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication.

Di Micco R, Fumagalli M, Cicalese A, Piccinin S, Gasparini P, Luise C, Schurra C, Garre' M, Nuciforo PG, Bensimon A, Maestro R, Pelicci PG, d'Adda di Fagagna F.

Nature. 2006 Nov 30;444(7119):638-42.

PMID:
17136094
2.

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.

Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, ├śrntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, Gorgoulis VG.

Nature. 2006 Nov 30;444(7119):633-7.

PMID:
17136093
3.

Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis.

Sarkisian CJ, Keister BA, Stairs DB, Boxer RB, Moody SE, Chodosh LA.

Nat Cell Biol. 2007 May;9(5):493-505. Epub 2007 Apr 22.

PMID:
17450133
4.

Cellular senescence in the development and treatment of cancer.

Saretzki G.

Curr Pharm Des. 2010 Jan;16(1):79-100. Review.

PMID:
20214620
5.

DNA damage signalling guards against activated oncogenes and tumour progression.

Bartek J, Bartkova J, Lukas J.

Oncogene. 2007 Dec 10;26(56):7773-9. Review.

PMID:
18066090
6.

Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells.

Santoriello C, Deflorian G, Pezzimenti F, Kawakami K, Lanfrancone L, d'Adda di Fagagna F, Mione M.

Dis Model Mech. 2009 Jan-Feb;2(1-2):56-67. doi: 10.1242/dmm.001016. Epub 2008 Dec 22.

7.

Oncogene-induced cellular senescence.

Chandeck C, Mooi WJ.

Adv Anat Pathol. 2010 Jan;17(1):42-8. doi: 10.1097/PAP.0b013e3181c66f4e. Review.

PMID:
20032638
8.

Retinoblastoma loss modulates DNA damage response favoring tumor progression.

Seoane M, Iglesias P, Gonzalez T, Dominguez F, Fraga M, Aliste C, Forteza J, Costoya JA.

PLoS One. 2008;3(11):e3632. doi: 10.1371/journal.pone.0003632. Epub 2008 Nov 5.

9.

Oxidation in the nucleotide pool, the DNA damage response and cellular senescence: Defective bricks build a defective house.

Rai P.

Mutat Res. 2010 Nov 28;703(1):71-81. doi: 10.1016/j.mrgentox.2010.07.010. Epub 2010 Jul 29. Review. Erratum in: Mutat Res. 2011 Sep 18;724(1-2):88.

PMID:
20673809
10.

Normal cellular senescence and cancer susceptibility in mice genetically deficient in Ras-induced senescence-1 (Ris1).

Nieto M, Barradas M, Criado LM, Flores JM, Serrano M, Llano E.

Oncogene. 2007 Mar 15;26(12):1673-80. Epub 2006 Sep 11.

PMID:
16964279
11.

Breaking news: high-speed race ends in arrest--how oncogenes induce senescence.

Di Micco R, Fumagalli M, d'Adda di Fagagna F.

Trends Cell Biol. 2007 Nov;17(11):529-36. Epub 2007 Nov 5. Review.

PMID:
17980599
12.

Cellular senescence in vivo: a barrier to tumorigenesis.

Prieur A, Peeper DS.

Curr Opin Cell Biol. 2008 Apr;20(2):150-5. doi: 10.1016/j.ceb.2008.01.007. Epub 2008 Mar 18. Review.

PMID:
18353625
13.

Oncogene-induced senescence pathways weave an intricate tapestry.

Yaswen P, Campisi J.

Cell. 2007 Jan 26;128(2):233-4. Review.

14.

Chronic NF-kappaB activation delays RasV12-induced premature senescence of human fibroblasts by suppressing the DNA damage checkpoint response.

Batsi C, Markopoulou S, Vartholomatos G, Georgiou I, Kanavaros P, Gorgoulis VG, Marcu KB, Kolettas E.

Mech Ageing Dev. 2009 Jul;130(7):409-19. doi: 10.1016/j.mad.2009.04.002. Epub 2009 May 3.

15.

DNA damage response activation in mouse embryonic fibroblasts undergoing replicative senescence and following spontaneous immortalization.

Di Micco R, Cicalese A, Fumagalli M, Dobreva M, Verrecchia A, Pelicci PG, di Fagagna Fd.

Cell Cycle. 2008 Nov 15;7(22):3601-6. Epub 2008 Nov 8.

PMID:
19001874
16.

A population of BJ fibroblasts escaped from Ras-induced senescence susceptible to transformation.

Kohsaka S, Sasai K, Takahashi K, Akagi T, Tanino M, Kimura T, Nishihara H, Tanaka S.

Biochem Biophys Res Commun. 2011 Jul 15;410(4):878-84. doi: 10.1016/j.bbrc.2011.06.082. Epub 2011 Jun 15.

PMID:
21703241
17.

Interferon-gamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells.

Kim KS, Kang KW, Seu YB, Baek SH, Kim JR.

Mech Ageing Dev. 2009 Mar;130(3):179-88. doi: 10.1016/j.mad.2008.11.004. Epub 2008 Nov 21.

PMID:
19071156
18.

Oncogene-induced senescence: the bright and dark side of the response.

Gorgoulis VG, Halazonetis TD.

Curr Opin Cell Biol. 2010 Dec;22(6):816-27. doi: 10.1016/j.ceb.2010.07.013. Epub 2010 Sep 16. Review.

PMID:
20807678
19.

Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence.

Larsson LG.

Semin Cancer Biol. 2011 Dec;21(6):367-76. doi: 10.1016/j.semcancer.2011.10.005. Epub 2011 Oct 24. Review.

PMID:
22037160
20.

Myc and Ras oncogenes engage different energy metabolism programs and evoke distinct patterns of oxidative and DNA replication stress.

Maya-Mendoza A, Ostrakova J, Kosar M, Hall A, Duskova P, Mistrik M, Merchut-Maya JM, Hodny Z, Bartkova J, Christensen C, Bartek J.

Mol Oncol. 2015 Mar;9(3):601-16. doi: 10.1016/j.molonc.2014.11.001. Epub 2014 Nov 15.

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