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Items: 1 to 20 of 84

1.

PET imaging with [11C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat.

Imaizumi M, Kim HJ, Zoghbi SS, Briard E, Hong J, Musachio JL, Ruetzler C, Chuang DM, Pike VW, Innis RB, Fujita M.

Neurosci Lett. 2007 Jan 16;411(3):200-5. Epub 2006 Nov 28.

PMID:
17127001
2.

Acute neuroinflammation in a clinically relevant focal cortical ischemic stroke model in rat: longitudinal positron emission tomography and immunofluorescent tracking.

Tóth M, Little P, Arnberg F, Häggkvist J, Mulder J, Halldin C, Gulyás B, Holmin S.

Brain Struct Funct. 2016 Apr;221(3):1279-90. doi: 10.1007/s00429-014-0970-y. Epub 2015 Jan 20.

PMID:
25601153
3.

Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors.

Imaizumi M, Briard E, Zoghbi SS, Gourley JP, Hong J, Fujimura Y, Pike VW, Innis RB, Fujita M.

Neuroimage. 2008 Feb 1;39(3):1289-98. Epub 2007 Oct 12.

4.

In vivo imaging of microglial activation using a peripheral benzodiazepine receptor ligand: [11C]PK-11195 and animal PET following ethanol injury in rat striatum.

Toyama H, Hatano K, Suzuki H, Ichise M, Momosaki S, Kudo G, Ito F, Kato T, Yamaguchi H, Katada K, Sawada M, Ito K.

Ann Nucl Med. 2008 Jun;22(5):417-24. doi: 10.1007/s12149-008-0136-1. Epub 2008 Jul 4.

PMID:
18600420
5.

[11C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat.

Walker MD, Dinelle K, Kornelsen R, Lee NV, Miao Q, Adam M, Takhar C, Mak E, Schulzer M, Farrer MJ, Sossi V.

J Cereb Blood Flow Metab. 2015 Aug;35(8):1331-8. doi: 10.1038/jcbfm.2015.54. Epub 2015 Apr 1.

7.

Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation.

Fujita M, Imaizumi M, Zoghbi SS, Fujimura Y, Farris AG, Suhara T, Hong J, Pike VW, Innis RB.

Neuroimage. 2008 Mar 1;40(1):43-52. Epub 2007 Nov 22.

8.

In vivo mapping of brain benzodiazepine receptor changes by positron emission tomography after focal ischemia in the anesthetized baboon.

Sette G, Baron JC, Young AR, Miyazawa H, Tillet I, Barré L, Travère JM, Derlon JM, MacKenzie ET.

Stroke. 1993 Dec;24(12):2046-57; discussion 2057-8.

9.

Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia.

Martín A, Boisgard R, Thézé B, Van Camp N, Kuhnast B, Damont A, Kassiou M, Dollé F, Tavitian B.

J Cereb Blood Flow Metab. 2010 Jan;30(1):230-41. doi: 10.1038/jcbfm.2009.205. Epub 2009 Sep 30.

10.

The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders.

Venneti S, Wang G, Nguyen J, Wiley CA.

J Neuropathol Exp Neurol. 2008 Oct;67(10):1001-10. doi: 10.1097/NEN.0b013e318188b204.

11.

Characterization of a novel acetamidobenzoxazolone-based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain.

Tiwari AK, Yui J, Fujinaga M, Kumata K, Shimoda Y, Yamasaki T, Xie L, Hatori A, Maeda J, Nengaki N, Zhang MR.

J Neurochem. 2014 May;129(4):712-20. doi: 10.1111/jnc.12670. Epub 2014 Feb 24.

12.

Pharmacokinetic Analysis of 11C-PBR28 in the Rat Model of Herpes Encephalitis: Comparison with (R)-11C-PK11195.

Parente A, Feltes PK, Vállez García D, Sijbesma JW, Moriguchi Jeckel CM, Dierckx RA, de Vries EF, Doorduin J.

J Nucl Med. 2016 May;57(5):785-91. doi: 10.2967/jnumed.115.165019. Epub 2016 Jan 28.

13.

The high affinity peripheral benzodiazepine receptor ligand DAA1106 binds specifically to microglia in a rat model of traumatic brain injury: implications for PET imaging.

Venneti S, Wagner AK, Wang G, Slagel SL, Chen X, Lopresti BJ, Mathis CA, Wiley CA.

Exp Neurol. 2007 Sep;207(1):118-27. Epub 2007 Jun 19.

14.

In vivo imaging of brain lesions with [(11)C]CLINME, a new PET radioligand of peripheral benzodiazepine receptors.

Boutin H, Chauveau F, Thominiaux C, Kuhnast B, Grégoire MC, Jan S, Trebossen R, Dollé F, Tavitian B, Mattner F, Katsifis A.

Glia. 2007 Nov 1;55(14):1459-68.

PMID:
17680643
15.

A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation.

Hughes JL, Jones PS, Beech JS, Wang D, Menon DK, Aigbirhio FI, Fryer TD, Baron JC.

Neuroimage. 2012 Feb 1;59(3):2007-16. doi: 10.1016/j.neuroimage.2011.10.060. Epub 2011 Oct 25.

PMID:
22056528
16.

Imaging of the translocator protein (18 kDa) in rat brain after ischemia using [11C]DAC with ultra-high specific activity.

Yui J, Hatori A, Yanamoto K, Takei M, Nengaki N, Kumata K, Kawamura K, Yamasaki T, Suzuki K, Zhang MR.

Synapse. 2010 Jun;64(6):488-93. doi: 10.1002/syn.20761. No abstract available.

PMID:
20175226
17.

A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation.

Venneti S, Lopresti BJ, Wang G, Slagel SL, Mason NS, Mathis CA, Fischer ML, Larsen NJ, Mortimer AD, Hastings TG, Smith AD, Zigmond MJ, Suhara T, Higuchi M, Wiley CA.

J Neurochem. 2007 Sep;102(6):2118-31. Epub 2007 Jun 7.

18.

Neuroinflammation extends brain tissue at risk to vital peri-infarct tissue: a double tracer [11C]PK11195- and [18F]FDG-PET study.

Schroeter M, Dennin MA, Walberer M, Backes H, Neumaier B, Fink GR, Graf R.

J Cereb Blood Flow Metab. 2009 Jun;29(6):1216-25. doi: 10.1038/jcbfm.2009.36. Epub 2009 Apr 8.

PMID:
19352400
19.

Imaging brain inflammation with [(11)C]PK11195 by PET and induction of the peripheral-type benzodiazepine receptor after transient focal ischemia in rats.

Rojas S, Martín A, Arranz MJ, Pareto D, Purroy J, Verdaguer E, Llop J, Gómez V, Gispert JD, Millán O, Chamorro A, Planas AM.

J Cereb Blood Flow Metab. 2007 Dec;27(12):1975-86. Epub 2007 Apr 25.

PMID:
17457364
20.

Mixed-affinity binding in humans with 18-kDa translocator protein ligands.

Owen DR, Gunn RN, Rabiner EA, Bennacef I, Fujita M, Kreisl WC, Innis RB, Pike VW, Reynolds R, Matthews PM, Parker CA.

J Nucl Med. 2011 Jan;52(1):24-32. doi: 10.2967/jnumed.110.079459. Epub 2010 Dec 13.

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