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Items: 1 to 20 of 3455

1.

Strategy for genotoxicity testing: hazard identification and risk assessment in relation to in vitro testing.

Thybaud V, Aardema M, Clements J, Dearfield K, Galloway S, Hayashi M, Jacobson-Kram D, Kirkland D, MacGregor JT, Marzin D, Ohyama W, Schuler M, Suzuki H, Zeiger E; Expert Working Group on Hazard Identification and Risk Assessment in Relation to In Vitro Testing.

Mutat Res. 2007 Feb 3;627(1):41-58. Epub 2006 Nov 27.

PMID:
17126066
2.

How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.

Kirkland D, Pfuhler S, Tweats D, Aardema M, Corvi R, Darroudi F, Elhajouji A, Glatt H, Hastwell P, Hayashi M, Kasper P, Kirchner S, Lynch A, Marzin D, Maurici D, Meunier JR, Müller L, Nohynek G, Parry J, Parry E, Thybaud V, Tice R, van Benthem J, Vanparys P, White P.

Mutat Res. 2007 Mar 30;628(1):31-55. Epub 2007 Jan 13.

PMID:
17293159
3.

Relevance and follow-up of positive results in in vitro genetic toxicity assays: an ILSI-HESI initiative.

Thybaud V, Aardema M, Casciano D, Dellarco V, Embry MR, Gollapudi BB, Hayashi M, Holsapple MP, Jacobson-Kram D, Kasper P, MacGregor JT, Rees R.

Mutat Res. 2007 Oct 4;633(2):67-79. Epub 2007 May 24.

PMID:
17616430
4.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
5.

Strategy for genotoxicity testing--metabolic considerations.

Ku WW, Bigger A, Brambilla G, Glatt H, Gocke E, Guzzie PJ, Hakura A, Honma M, Martus HJ, Obach RS, Roberts S; Strategy Expert Group, IWGT.

Mutat Res. 2007 Feb 3;627(1):59-77. Epub 2006 Dec 1.

PMID:
17141553
6.

Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity.

Kirkland D, Aardema M, Henderson L, Müller L.

Mutat Res. 2005 Jul 4;584(1-2):1-256. Erratum in: Mutat Res. 2005 Dec 7;588(1):70.

PMID:
15979392
7.

Follow-up testing of rodent carcinogens not positive in the standard genotoxicity testing battery: IWGT workgroup report.

Kasper P, Uno Y, Mauthe R, Asano N, Douglas G, Matthews E, Moore M, Mueller L, Nakajima M, Singer T, Speit G; IWGT Workgroup.

Mutat Res. 2007 Feb 3;627(1):106-16. Epub 2006 Nov 22. Review.

PMID:
17123861
8.

Testing strategies in mutagenicity and genetic toxicology: an appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes.

Kirkland DJ, Henderson L, Marzin D, Müller L, Parry JM, Speit G, Tweats DJ, Williams GM.

Mutat Res. 2005 Dec 30;588(2):88-105. Epub 2005 Dec 2. Review.

PMID:
16326131
9.

In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results.

Kirkland DJ, Aardema M, Banduhn N, Carmichael P, Fautz R, Meunier JR, Pfuhler S.

Mutagenesis. 2007 May;22(3):161-75. Epub 2007 Mar 16. Review.

PMID:
17369606
10.

Follow-up actions from positive results of in vitro genetic toxicity testing.

Dearfield KL, Thybaud V, Cimino MC, Custer L, Czich A, Harvey JS, Hester S, Kim JH, Kirkland D, Levy DD, Lorge E, Moore MM, Ouédraogo-Arras G, Schuler M, Suter W, Sweder K, Tarlo K, van Benthem J, van Goethem F, Witt KL.

Environ Mol Mutagen. 2011 Apr;52(3):177-204. doi: 10.1002/em.20617. Epub 2010 Oct 20. Review.

11.

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing.

Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Miyamae Y, Rojas E, Ryu JC, Sasaki YF.

Environ Mol Mutagen. 2000;35(3):206-21.

PMID:
10737956
12.

How to assess the mutagenic potential of cosmetic products without animal tests?

Speit G.

Mutat Res. 2009 Aug;678(2):108-12. doi: 10.1016/j.mrgentox.2009.04.006. Epub 2009 Apr 18.

PMID:
19379833
13.

In vivo rodent erythrocyte micronucleus assay. II. Some aspects of protocol design including repeated treatments, integration with toxicity testing, and automated scoring.

Hayashi M, MacGregor JT, Gatehouse DG, Adler ID, Blakey DH, Dertinger SD, Krishna G, Morita T, Russo A, Sutou S.

Environ Mol Mutagen. 2000;35(3):234-52.

PMID:
10737958
15.

Improvement of in vivo genotoxicity assessment: combination of acute tests and integration into standard toxicity testing.

Rothfuss A, Honma M, Czich A, Aardema MJ, Burlinson B, Galloway S, Hamada S, Kirkland D, Heflich RH, Howe J, Nakajima M, O'Donovan M, Plappert-Helbig U, Priestley C, Recio L, Schuler M, Uno Y, Martus HJ.

Mutat Res. 2011 Aug 16;723(2):108-20. doi: 10.1016/j.mrgentox.2010.12.005. Epub 2010 Dec 21.

PMID:
21182982
18.

Testing strategies to establish the safety of nanomaterials: conclusions of an ECETOC workshop.

Warheit DB, Borm PJ, Hennes C, Lademann J.

Inhal Toxicol. 2007 Jun;19(8):631-43.

PMID:
17510836
19.

Carcinogenicity categorization of chemicals-new aspects to be considered in a European perspective.

Bolt HM, Foth H, Hengstler JG, Degen GH.

Toxicol Lett. 2004 Jun 15;151(1):29-41. Review.

PMID:
15177638
20.

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