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Items: 1 to 20 of 118

1.

The molecular basis for ligand specificity in a mouse olfactory receptor: a network of functionally important residues.

Abaffy T, Malhotra A, Luetje CW.

J Biol Chem. 2007 Jan 12;282(2):1216-24. Epub 2006 Nov 17.

2.

Molecular similarities in the ligand binding pockets of an odorant receptor and the metabotropic glutamate receptors.

Kuang D, Yao Y, Wang M, Pattabiraman N, Kotra LP, Hampson DR.

J Biol Chem. 2003 Oct 24;278(43):42551-9. Epub 2003 Aug 11.

3.

Making sense of olfaction through predictions of the 3-D structure and function of olfactory receptors.

Floriano WB, Vaidehi N, Goddard WA 3rd.

Chem Senses. 2004 May;29(4):269-90.

PMID:
15150141
4.

Molecular modeling of ligand-receptor interactions in the OR5 olfactory receptor.

Singer MS, Shepherd GM.

Neuroreport. 1994 Jun 2;5(10):1297-300.

PMID:
7919185
5.

Molecular determinants of ligand selectivity in a vertebrate odorant receptor.

Luu P, Acher F, Bertrand HO, Fan J, Ngai J.

J Neurosci. 2004 Nov 10;24(45):10128-37.

6.

Functional analysis of a mammalian odorant receptor subfamily.

Abaffy T, Matsunami H, Luetje CW.

J Neurochem. 2006 Jun;97(5):1506-18. Epub 2006 Apr 5.

7.

The mouse eugenol odorant receptor: structural and functional plasticity of a broadly tuned odorant binding pocket.

Baud O, Etter S, Spreafico M, Bordoli L, Schwede T, Vogel H, Pick H.

Biochemistry. 2011 Feb 8;50(5):843-53. doi: 10.1021/bi1017396. Epub 2010 Dec 30.

PMID:
21142015
8.

Positive selection moments identify potential functional residues in human olfactory receptors.

Singer MS, Weisinger-Lewin Y, Lancet D, Shepherd GM.

Receptors Channels. 1996;4(3):141-7.

PMID:
9014237
9.

Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists.

Kim SK, Gao ZG, Van Rompaey P, Gross AS, Chen A, Van Calenbergh S, Jacobson KA.

J Med Chem. 2003 Nov 6;46(23):4847-59.

PMID:
14584936
10.

The unique ligand-binding pocket for the human prostacyclin receptor. Site-directed mutagenesis and molecular modeling.

Stitham J, Stojanovic A, Merenick BL, O'Hara KA, Hwa J.

J Biol Chem. 2003 Feb 7;278(6):4250-7. Epub 2002 Nov 21.

12.

Binding specificity of locust odorant binding protein and its key binding site for initial recognition of alcohols.

Jiang QY, Wang WX, Zhang Z, Zhang L.

Insect Biochem Mol Biol. 2009 Jul;39(7):440-7. doi: 10.1016/j.ibmb.2009.04.004. Epub 2009 Apr 17.

PMID:
19376226
13.

Molecular modeling and docking studies of human 5-hydroxytryptamine 2A (5-HT2A) receptor for the identification of hotspots for ligand binding.

Kanagarajadurai K, Malini M, Bhattacharya A, Panicker MM, Sowdhamini R.

Mol Biosyst. 2009 Dec;5(12):1877-88. doi: 10.1039/b906391a. Epub 2009 Sep 8.

PMID:
19763327
14.

Tweaking agonist efficacy at N-methyl-D-aspartate receptors by site-directed mutagenesis.

Hansen KB, Clausen RP, Bjerrum EJ, Bechmann C, Greenwood JR, Christensen C, Kristensen JL, Egebjerg J, Bräuner-Osborne H.

Mol Pharmacol. 2005 Dec;68(6):1510-23. Epub 2005 Aug 30.

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17.

Structural insight into the specific interaction between murine SHPS-1/SIRP alpha and its ligand CD47.

Nakaishi A, Hirose M, Yoshimura M, Oneyama C, Saito K, Kuki N, Matsuda M, Honma N, Ohnishi H, Matozaki T, Okada M, Nakagawa A.

J Mol Biol. 2008 Jan 18;375(3):650-60. Epub 2007 Nov 7.

PMID:
18045614
19.

Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short chain fatty acids.

Stoddart LA, Smith NJ, Jenkins L, Brown AJ, Milligan G.

J Biol Chem. 2008 Nov 21;283(47):32913-24. doi: 10.1074/jbc.M805601200. Epub 2008 Sep 18.

20.

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