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Items: 1 to 20 of 187

1.

Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes.

Tan Y, Raychaudhuri P, Costa RH.

Mol Cell Biol. 2007 Feb;27(3):1007-16. Epub 2006 Nov 13.

2.

Forkhead box M1 regulates the transcriptional network of genes essential for mitotic progression and genes encoding the SCF (Skp2-Cks1) ubiquitin ligase.

Wang IC, Chen YJ, Hughes D, Petrovic V, Major ML, Park HJ, Tan Y, Ackerson T, Costa RH.

Mol Cell Biol. 2005 Dec;25(24):10875-94.

3.

Two-fold elevation of expression of FoxM1 transcription factor in mouse embryonic fibroblasts enhances cell cycle checkpoint activity by stimulating p21 and Chk1 transcription.

Tan Y, Chen Y, Yu L, Zhu H, Meng X, Huang X, Meng L, Ding M, Wang Z, Shan L.

Cell Prolif. 2010 Oct;43(5):494-504. doi: 10.1111/j.1365-2184.2010.00699.x.

PMID:
20887555
4.

ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance.

Millour J, de Olano N, Horimoto Y, Monteiro LJ, Langer JK, Aligue R, Hajji N, Lam EW.

Mol Cancer Ther. 2011 Jun;10(6):1046-58. doi: 10.1158/1535-7163.MCT-11-0024. Epub 2011 Apr 25.

5.

FOXM1 confers acquired cisplatin resistance in breast cancer cells.

Kwok JM, Peck B, Monteiro LJ, Schwenen HD, Millour J, Coombes RC, Myatt SS, Lam EW.

Mol Cancer Res. 2010 Jan;8(1):24-34. doi: 10.1158/1541-7786.MCR-09-0432. Epub 2010 Jan 12.

6.

Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression.

Fu Z, Malureanu L, Huang J, Wang W, Li H, van Deursen JM, Tindall DJ, Chen J.

Nat Cell Biol. 2008 Sep;10(9):1076-82. doi: 10.1038/ncb1767.

7.

TIS21(/BTG2/PC3) accelerates the repair of DNA double strand breaks by enhancing Mre11 methylation and blocking damage signal transfer to the Chk2(T68)-p53(S20) pathway.

Choi KS, Kim JY, Lim SK, Choi YW, Kim YH, Kang SY, Park TJ, Lim IK.

DNA Repair (Amst). 2012 Dec 1;11(12):965-75. doi: 10.1016/j.dnarep.2012.09.009. Epub 2012 Oct 22.

PMID:
23089312
8.

p53 negatively regulates expression of FoxM1.

Pandit B, Halasi M, Gartel AL.

Cell Cycle. 2009 Oct 15;8(20):3425-7. Epub 2009 Oct 25.

PMID:
19806025
9.

FoxM1 regulates growth factor-induced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression.

Petrovic V, Costa RH, Lau LF, Raychaudhuri P, Tyner AL.

J Biol Chem. 2008 Jan 4;283(1):453-60. Epub 2007 Nov 5.

10.

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.

J Cell Sci. 2005 Apr 15;118(Pt 8):1629-39. Epub 2005 Mar 22. Retraction in: J Cell Sci. 2015 Mar 1;128(5):1064.

11.

The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment.

Monteiro LJ, Khongkow P, Kongsema M, Morris JR, Man C, Weekes D, Koo CY, Gomes AR, Pinto PH, Varghese V, Kenny LM, Charles Coombes R, Freire R, Medema RH, Lam EW.

Oncogene. 2013 Sep 26;32(39):4634-45. doi: 10.1038/onc.2012.491. Epub 2012 Oct 29.

12.

MDC1 is a mediator of the mammalian DNA damage checkpoint.

Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ.

Nature. 2003 Feb 27;421(6926):961-6.

PMID:
12607005
13.
14.

The forkhead box m1 transcription factor is essential for embryonic development of pulmonary vasculature.

Kim IM, Ramakrishna S, Gusarova GA, Yoder HM, Costa RH, Kalinichenko VV.

J Biol Chem. 2005 Jun 10;280(23):22278-86. Epub 2005 Apr 6.

15.

Activation of DNA damage response signaling in mouse embryonic stem cells.

Chuykin IA, Lianguzova MS, Pospelova TV, Pospelov VA.

Cell Cycle. 2008 Sep 15;7(18):2922-8. Epub 2008 Sep 30.

PMID:
18787397
16.
17.

E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.

Powers JT, Hong S, Mayhew CN, Rogers PM, Knudsen ES, Johnson DG.

Mol Cancer Res. 2004 Apr;2(4):203-14.

18.

FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance.

Khongkow P, Karunarathna U, Khongkow M, Gong C, Gomes AR, Yag├╝e E, Monteiro LJ, Kongsema M, Zona S, Man EP, Tsang JW, Coombes RC, Wu KJ, Khoo US, Medema RH, Freire R, Lam EW.

Oncogene. 2014 Aug 7;33(32):4144-55. doi: 10.1038/onc.2013.457. Epub 2013 Oct 21.

19.

DNA damage-induced activation of p53 by the checkpoint kinase Chk2.

Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW.

Science. 2000 Mar 10;287(5459):1824-7.

20.

CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage.

Huang H, Regan KM, Lou Z, Chen J, Tindall DJ.

Science. 2006 Oct 13;314(5797):294-7.

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