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Downregulation of cyclooxygenase-2 expression and activation of caspase-3 are involved in peroxisome proliferator-activated receptor-gamma agonists induced apoptosis in human monocyte leukemia cells in vitro.

Liu JJ, Liu PQ, Lin DJ, Xiao RZ, Huang M, Li XD, He Y, Huang RW. Liu JJ, et al. Ann Hematol. 2007 Mar;86(3):173-83. doi: 10.1007/s00277-006-0205-2. Epub 2006 Nov 7. Ann Hematol. 2007. PMID: 17089125

Differential modulation of COX-2 expression in A549 airway epithelial cells by structurally distinct PPAR(gamma) agonists: evidence for disparate functional effects which are independent of NF-(kappa)B and PPAR(gamma).

Patel KM, Wright KL, Whittaker P, Chakravarty P, Watson ML, Ward SG. Patel KM, et al. Cell Signal. 2005 Sep;17(9):1098-110. doi: 10.1016/j.cellsig.2004.12.002. Epub 2005 Jan 7. Cell Signal. 2005. PMID: 15993751

Rosiglitazone and PPAR-gamma overexpression protect mitochondrial membrane potential and prevent apoptosis by upregulating anti-apoptotic Bcl-2 family proteins.

Wu JS, Lin TN, Wu KK. Wu JS, et al. J Cell Physiol. 2009 Jul;220(1):58-71. doi: 10.1002/jcp.21730. J Cell Physiol. 2009. PMID: 19229877

Activation of peroxisome proliferator-activated receptor-gamma by troglitazone (TGZ) inhibits human lung cell growth.

Li M, Lee TW, Mok TS, Warner TD, Yim AP, Chen GG. Li M, et al. J Cell Biochem. 2005 Nov 1;96(4):760-74. doi: 10.1002/jcb.20474. J Cell Biochem. 2005. PMID: 16149072

Relationship between peroxisome proliferator-activated receptor-gamma expression and differentiation of human esophageal squamous cell carcinoma.

Takashima T, Fujiwara Y, Hamaguchi M, Sasaki E, Tominaga K, Watanabe T, Oshitani N, Higuchi K, Arakawa T. Takashima T, et al. Oncol Rep. 2005 Apr;13(4):601-6. Oncol Rep. 2005. PMID: 15756430

Activation of peroxisome proliferator-activated receptor gamma inhibits cell growth via apoptosis and arrest of the cell cycle in human colorectal cancer.

Lin MS, Chen WC, Bai X, Wang YD. Lin MS, et al. J Dig Dis. 2007 May;8(2):82-8. doi: 10.1111/j.1443-9573.2007.00290.x. J Dig Dis. 2007. PMID: 17532820

Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells.

Liu J, Lu H, Huang R, Lin D, Wu X, Lin Q, Wu X, Zheng J, Pan X, Peng J, Song Y, Zhang M, Hou M, Chen F. Liu J, et al. Cancer Chemother Pharmacol. 2005 Oct;56(4):400-8. doi: 10.1007/s00280-005-1029-9. Epub 2005 Apr 19. Cancer Chemother Pharmacol. 2005. PMID: 15838654

Suppression of chondrosarcoma cells by 15-deoxy-Delta 12,14-prostaglandin J2 is associated with altered expression of Bax/Bcl-xL and p21.

Shen ZN, Nishida K, Doi H, Oohashi T, Hirohata S, Ozaki T, Yoshida A, Ninomiya Y, Inoue H. Shen ZN, et al. Biochem Biophys Res Commun. 2005 Mar 11;328(2):375-82. doi: 10.1016/j.bbrc.2004.12.186. Biochem Biophys Res Commun. 2005. PMID: 15694358

Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway.

Kim EJ, Park KS, Chung SY, Sheen YY, Moon DC, Song YS, Kim KS, Song S, Yun YP, Lee MK, Oh KW, Yoon DY, Hong JT. Kim EJ, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):505-17. doi: 10.1124/jpet.103.053876. Epub 2003 Sep 9. J Pharmacol Exp Ther. 2003. PMID: 12966153

3T3-L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator-activated receptor-gamma-dependent and mediated by the caspase-3-dependent apoptotic pathway.

Xiao Y, Yuan T, Yao W, Liao K. Xiao Y, et al. FEBS J. 2010 Feb;277(3):687-96. doi: 10.1111/j.1742-4658.2009.07514.x. Epub 2009 Dec 29. FEBS J. 2010. PMID: 20050918 Free article.

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