Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 96

1.

EDD mediates DNA damage-induced activation of CHK2.

Henderson MJ, Munoz MA, Saunders DN, Clancy JL, Russell AJ, Williams B, Pappin D, Khanna KK, Jackson SP, Sutherland RL, Watts CK.

J Biol Chem. 2006 Dec 29;281(52):39990-40000. Epub 2006 Oct 30.

2.

The E3 ubiquitin ligase EDD regulates S-phase and G(2)/M DNA damage checkpoints.

Munoz MA, Saunders DN, Henderson MJ, Clancy JL, Russell AJ, Lehrbach G, Musgrove EA, Watts CK, Sutherland RL.

Cell Cycle. 2007 Dec 15;6(24):3070-7. Epub 2007 Sep 7.

PMID:
18073532
3.

Regulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379.

Lovly CM, Yan L, Ryan CE, Takada S, Piwnica-Worms H.

Mol Cell Biol. 2008 Oct;28(19):5874-85. doi: 10.1128/MCB.00821-08. Epub 2008 Jul 21.

4.

TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68.

Wei JH, Chou YF, Ou YH, Yeh YH, Tyan SW, Sun TP, Shen CY, Shieh SY.

J Biol Chem. 2005 Mar 4;280(9):7748-57. Epub 2004 Dec 23.

5.

Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage.

Bahassi el M, Myer DL, McKenney RJ, Hennigan RF, Stambrook PJ.

Mutat Res. 2006 Apr 11;596(1-2):166-76. Epub 2006 Feb 14.

PMID:
16481012
6.

Chk2 activation and phosphorylation-dependent oligomerization.

Xu X, Tsvetkov LM, Stern DF.

Mol Cell Biol. 2002 Jun;22(12):4419-32.

7.

ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.

Pabla N, Huang S, Mi QS, Daniel R, Dong Z.

J Biol Chem. 2008 Mar 7;283(10):6572-83. Epub 2007 Dec 27. Erratum in: J Biol Chem. 2008 May 30;283(22):15512.

8.

EDD, the human hyperplastic discs protein, has a role in progesterone receptor coactivation and potential involvement in DNA damage response.

Henderson MJ, Russell AJ, Hird S, Muñoz M, Clancy JL, Lehrbach GM, Calanni ST, Jans DA, Sutherland RL, Watts CK.

J Biol Chem. 2002 Jul 19;277(29):26468-78. Epub 2002 May 13.

9.

ATM-dependent CHK2 activation induced by anticancer agent, irofulven.

Wang J, Wiltshire T, Wang Y, Mikell C, Burks J, Cunningham C, Van Laar ES, Waters SJ, Reed E, Wang W.

J Biol Chem. 2004 Sep 17;279(38):39584-92. Epub 2004 Jul 20.

10.

Interdependent phosphorylation within the kinase domain T-loop Regulates CHK2 activity.

Guo X, Ward MD, Tiedebohl JB, Oden YM, Nyalwidhe JO, Semmes OJ.

J Biol Chem. 2010 Oct 22;285(43):33348-57. doi: 10.1074/jbc.M110.149609. Epub 2010 Aug 16.

11.

DNA damage regulates Chk2 association with chromatin.

Li J, Stern DF.

J Biol Chem. 2005 Nov 11;280(45):37948-56. Epub 2005 Sep 8.

12.

Regulation of CHK2 by DNA-dependent protein kinase.

Li J, Stern DF.

J Biol Chem. 2005 Mar 25;280(12):12041-50. Epub 2005 Jan 24.

13.

STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.

Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.

J Cell Sci. 2005 Apr 15;118(Pt 8):1629-39. Epub 2005 Mar 22. Retraction in: J Cell Sci. 2015 Mar 1;128(5):1064.

14.

DNA damage-induced cell cycle regulation and function of novel Chk2 phosphoresidues.

Buscemi G, Carlessi L, Zannini L, Lisanti S, Fontanella E, Canevari S, Delia D.

Mol Cell Biol. 2006 Nov;26(21):7832-45. Epub 2006 Aug 28.

15.

Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable.

de Vries HI, Uyetake L, Lemstra W, Brunsting JF, Su TT, Kampinga HH, Sibon OC.

J Cell Sci. 2005 May 1;118(Pt 9):1833-42.

16.

Radioprotection by hymenialdisine-derived checkpoint kinase 2 inhibitors.

Nguyen TN, Saleem RS, Luderer MJ, Hovde S, Henry RW, Tepe JJ.

ACS Chem Biol. 2012 Jan 20;7(1):172-84. doi: 10.1021/cb200320c. Epub 2011 Oct 24.

PMID:
22004065
17.

The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover.

Bohgaki M, Hakem A, Halaby MJ, Bohgaki T, Li Q, Bissey PA, Shloush J, Kislinger T, Sanchez O, Sheng Y, Hakem R.

Cell Death Differ. 2013 Jun;20(6):812-22. doi: 10.1038/cdd.2013.7. Epub 2013 Mar 1.

18.
19.
20.

Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner.

Gibson SL, Bindra RS, Glazer PM.

Cancer Res. 2005 Dec 1;65(23):10734-41.

Supplemental Content

Support Center