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Items: 1 to 20 of 231

1.

Mitochondria contribute to LPS-induced MAPK activation via uncoupling protein UCP2 in macrophages.

Emre Y, Hurtaud C, Nübel T, Criscuolo F, Ricquier D, Cassard-Doulcier AM.

Biochem J. 2007 Mar 1;402(2):271-8.

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Persistent nuclear factor-kappa B activation in Ucp2-/- mice leads to enhanced nitric oxide and inflammatory cytokine production.

Bai Y, Onuma H, Bai X, Medvedev AV, Misukonis M, Weinberg JB, Cao W, Robidoux J, Floering LM, Daniel KW, Collins S.

J Biol Chem. 2005 May 13;280(19):19062-9. Epub 2005 Mar 9.

4.

The mitochondrial uncoupling protein-2 is a master regulator of both M1 and M2 microglial responses.

De Simone R, Ajmone-Cat MA, Pandolfi M, Bernardo A, De Nuccio C, Minghetti L, Visentin S.

J Neurochem. 2015 Oct;135(1):147-56. doi: 10.1111/jnc.13244. Epub 2015 Aug 3.

5.

Uncoupling protein 2 negatively regulates mitochondrial reactive oxygen species generation and induces phosphatase-mediated anti-inflammatory response in experimental visceral leishmaniasis.

Basu Ball W, Kar S, Mukherjee M, Chande AG, Mukhopadhyaya R, Das PK.

J Immunol. 2011 Aug 1;187(3):1322-32. doi: 10.4049/jimmunol.1004237. Epub 2011 Jun 24.

6.

Stress-Induced Glucocorticoid Release Upregulates Uncoupling Protein-2 Expression and Enhances Resistance to Endotoxin-Induced Lethality.

Kasahara E, Sekiyama A, Hori M, Kuratsune D, Fujisawa N, Chida D, Hiramoto K, Li J, Okamura H, Inoue M, Kitagawa S.

Neuroimmunomodulation. 2015;22(5):279-92. doi: 10.1159/000368802. Epub 2015 Jan 28.

PMID:
26074181
7.

Role of uncoupling protein UCP2 in cell-mediated immunity: how macrophage-mediated insulitis is accelerated in a model of autoimmune diabetes.

Emre Y, Hurtaud C, Karaca M, Nubel T, Zavala F, Ricquier D.

Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19085-90. Epub 2007 Nov 15.

8.

Mitochondrial uncoupling protein 2 protects splenocytes from oxidative stress-induced apoptosis during pathogen activation.

Cao T, Dong Y, Tang R, Chen J, Zhang CY, Zen K.

Cell Immunol. 2013 Nov-Dec;286(1-2):39-44. doi: 10.1016/j.cellimm.2013.10.002. Epub 2013 Oct 19.

PMID:
24291389
9.

Uncoupling protein UCP2: when mitochondrial activity meets immunity.

Emre Y, Nübel T.

FEBS Lett. 2010 Apr 16;584(8):1437-42. doi: 10.1016/j.febslet.2010.03.014. Epub 2010 Mar 15. Review.

10.

Uncoupling protein 2 plays an important role in nitric oxide production of lipopolysaccharide-stimulated macrophages.

Kizaki T, Suzuki K, Hitomi Y, Taniguchi N, Saitoh D, Watanabe K, Onoé K, Day NK, Good RA, Ohno H.

Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9392-7. Epub 2002 Jun 27.

11.

Uncoupling lipid metabolism from inflammation through fatty acid binding protein-dependent expression of UCP2.

Xu H, Hertzel AV, Steen KA, Wang Q, Suttles J, Bernlohr DA.

Mol Cell Biol. 2015 Mar;35(6):1055-65. doi: 10.1128/MCB.01122-14. Epub 2015 Jan 12.

12.

Mitochondrial ROS govern the LPS-induced pro-inflammatory response in microglia cells by regulating MAPK and NF-κB pathways.

Park J, Min JS, Kim B, Chae UB, Yun JW, Choi MS, Kong IK, Chang KT, Lee DS.

Neurosci Lett. 2015 Jan 1;584:191-6. doi: 10.1016/j.neulet.2014.10.016. Epub 2014 Oct 22.

PMID:
25459294
13.

Uncoupling Protein 2 Increases Susceptibility to Lipopolysaccharide-Induced Acute Lung Injury in Mice.

Wang Q, Wang J, Hu M, Yang Y, Guo L, Xu J, Lei C, Jiao Y, Xu J.

Mediators Inflamm. 2016;2016:9154230. doi: 10.1155/2016/9154230. Epub 2016 Feb 7.

14.

Uncoupling protein-2 protects endothelial function in diet-induced obese mice.

Tian XY, Wong WT, Xu A, Lu Y, Zhang Y, Wang L, Cheang WS, Wang Y, Yao X, Huang Y.

Circ Res. 2012 Apr 27;110(9):1211-6. doi: 10.1161/CIRCRESAHA.111.262170. Epub 2012 Mar 29.

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16.

The role of MyD88 and TLR4 in the LPS-mimetic activity of Taxol.

Byrd-Leifer CA, Block EF, Takeda K, Akira S, Ding A.

Eur J Immunol. 2001 Aug;31(8):2448-57.

18.

Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage.

Kim HG, Yoon DH, Lee WH, Han SK, Shrestha B, Kim CH, Lim MH, Chang W, Lim S, Choi S, Song WO, Sung JM, Hwang KC, Kim TW.

J Ethnopharmacol. 2007 Dec 3;114(3):307-15. Epub 2007 Aug 19.

PMID:
17936530
19.

Increased activity of mitochondrial uncoupling protein 2 improves stress resistance in cultured endothelial cells exposed in vitro to high glucose levels.

Koziel A, Sobieraj I, Jarmuszkiewicz W.

Am J Physiol Heart Circ Physiol. 2015 Jul 1;309(1):H147-56. doi: 10.1152/ajpheart.00759.2014. Epub 2015 Apr 24.

20.

Ameliorating Endothelial Mitochondrial Dysfunction Restores Coronary Function via Transient Receptor Potential Vanilloid 1-Mediated Protein Kinase A/Uncoupling Protein 2 Pathway.

Xiong S, Wang P, Ma L, Gao P, Gong L, Li L, Li Q, Sun F, Zhou X, He H, Chen J, Yan Z, Liu D, Zhu Z.

Hypertension. 2016 Feb;67(2):451-60. doi: 10.1161/HYPERTENSIONAHA.115.06223. Epub 2015 Dec 14.

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