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Mutation of an IKK phosphorylation site within the transactivation domain of REL in two patients with B-cell lymphoma enhances REL's in vitro transforming activity.

Starczynowski DT, Trautmann H, Pott C, Harder L, Arnold N, Africa JA, Leeman JR, Siebert R, Gilmore TD.

Oncogene. 2007 Apr 26;26(19):2685-94. Epub 2006 Oct 30.


Mutant envelope residues confer a transactivation function onto N-terminal sequences of the v-Rel oncoprotein.

Epinat JC, Kazandjian D, Harkness DD, Petros S, Dave J, White DW, Gilmore TD.

Oncogene. 2000 Feb 3;19(5):599-607.


The human B-cell lymphoma cell line RC-K8 has multiple genetic alterations that dysregulate the Rel/NF-kappaB signal transduction pathway.

Kalaitzidis D, Davis RE, Rosenwald A, Staudt LM, Gilmore TD.

Oncogene. 2002 Dec 12;21(57):8759-68.


NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes.

Feuerhake F, Kutok JL, Monti S, Chen W, LaCasce AS, Cattoretti G, Kurtin P, Pinkus GS, de Leval L, Harris NL, Savage KJ, Neuberg D, Habermann TM, Dalla-Favera R, Golub TR, Aster JC, Shipp MA.

Blood. 2005 Aug 15;106(4):1392-9. Epub 2005 May 3.


Identification of NF-kappaB in the marine fish Stenotomus chrysops and examination of its activation by aryl hydrocarbon receptor agonists.

Schlezinger JJ, Blickarz CE, Mann KK, Doerre S, Stegeman JJ.

Chem Biol Interact. 2000 May 1;126(2):137-57.


Epothilones induce human colon cancer SW620 cell apoptosis via the tubulin polymerization independent activation of the nuclear factor-kappaB/IkappaB kinase signal pathway.

Lee SH, Son SM, Son DJ, Kim SM, Kim TJ, Song S, Moon DC, Lee HW, Ryu JC, Yoon DY, Hong JT.

Mol Cancer Ther. 2007 Oct;6(10):2786-97.


Tumor necrosis factor-alpha induces MMP-9 expression via p42/p44 MAPK, JNK, and nuclear factor-kappaB in A549 cells.

Lin CC, Tseng HW, Hsieh HL, Lee CW, Wu CY, Cheng CY, Yang CM.

Toxicol Appl Pharmacol. 2008 Jun 15;229(3):386-98. doi: 10.1016/j.taap.2008.01.032. Epub 2008 Feb 9.


Histone acetyltransferase p300 is a coactivator for transcription factor REL and is C-terminally truncated in the human diffuse large B-cell lymphoma cell line RC-K8.

Garbati MR, Alço G, Gilmore TD.

Cancer Lett. 2010 May 28;291(2):237-45. doi: 10.1016/j.canlet.2009.10.018. Epub 2009 Nov 30.

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