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Items: 1 to 20 of 129

1.

AZT and AZT-monophosphate prodrugs incorporating HIV-protease substrate fragment: synthesis and evaluation as specific drug delivery systems.

Liotard JF, Mehiri M, Di Giorgio A, Boggetto N, Reboud-Ravaux M, Aubertin AM, Condom R, Patino N.

Antivir Chem Chemother. 2006;17(4):193-213.

PMID:
17066898
2.
3.
4.

Intracellular metabolism of CycloSaligenyl 3'-azido-2', 3'-dideoxythymidine monophosphate, a prodrug of 3'-azido-2', 3'-dideoxythymidine (zidovudine).

Balzarini J, Naesens L, Aquaro S, Knispel T, Perno C, De Clercq E, Meier C.

Mol Pharmacol. 1999 Dec;56(6):1354-61.

5.

Cellular metabolism in lymphocytes of a novel thioether-phospholipid-AZT conjugate with anti-HIV-1 activity.

Kucera GL, Goff CL, Iyer N, Morris-Natschke S, Ishaq KS, Wyrick SD, Fleming RA, Kucera LS.

Antiviral Res. 2001 May;50(2):129-37.

PMID:
11369433
6.

Low-dose, sublingual AZT-monophosphate therapy for HIV+ patients?

Johnson S.

Med Hypotheses. 2001 Mar;56(3):409-10.

PMID:
11359372
7.

Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine.

Saboulard D, Naesens L, Cahard D, Salgado A, Pathirana R, Velazquez S, McGuigan C, De Clercq E, Balzarini J.

Mol Pharmacol. 1999 Oct;56(4):693-704.

9.

Novel approaches for designing 5'-O-ester prodrugs of 3'-azido-2', 3'-dideoxythymidine (AZT).

Parang K, Wiebe LI, Knaus EE.

Curr Med Chem. 2000 Oct;7(10):995-1039. Review.

10.

Anti-HIV pronucleotides: decomposition pathways and correlation with biological activities.

Egron D, Lefebvre I, Périgaud C, Beltran T, Pompon A, Gosselin G, Aubertin AM, Imbach JL.

Bioorg Med Chem Lett. 1998 May 5;8(9):1045-50.

PMID:
9871705
12.

Dipeptide derivatives of AZT: synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity.

Santos C, Morais J, Gouveia L, de Clercq E, Pannecouque C, Nielsen CU, Steffansen B, Moreira R, Gomes P.

ChemMedChem. 2008 Jun;3(6):970-8. doi: 10.1002/cmdc.200800012.

PMID:
18389514
13.

[Synthesis, properties and anti-HIV activity of novel lipophilic 3'-azido-3'-deoxythymidine conjugates containing functional phosphoric linkages].

Shastina NS, Mal'tseva TIu, D'iakova LN, Lobach OA, Chataeva MS, Nosik DN, Shvetz VI.

Bioorg Khim. 2013 Mar-Apr;39(2):184-93. Russian.

PMID:
23964518
14.

5'-Hydrogenphosphonates of anti-HIV nucleoside analogues revisited: controversial mode of action.

Gosselin G, Périgaud C, Lefebvre I, Pompon A, Aubertin AM, Kirn A, Szabo T, Stawinski J, Imbach JL.

Antiviral Res. 1993 Oct;22(2-3):143-53.

PMID:
8279809
15.

New 3'-azido-3'-deoxythymidin-5'-yl O-(omega-hydroxyalkyl) carbonate prodrugs: synthesis and anti-HIV evaluation.

Vlieghe P, Bihel F, Clerc T, Pannecouque C, Witvrouw M, De Clercq E, Salles JP, Chermann JC, Kraus JL.

J Med Chem. 2001 Mar 1;44(5):777-86.

PMID:
11262088
16.

AZT-5'-(p-bromophenyl methoxyalaninyl phosphate) as a potent and non-toxic anti-human immunodeficiency virus agent.

Jan ST, Zhu Z, Tai HL, Shih MJ, Venkatachalam TK, Uckun FM.

Antivir Chem Chemother. 1999 Jan;10(1):47-52.

PMID:
10079879
17.

Synthesis, anti-HIV activity, and stability studies of 5'-phosphorofluoridate derivatives of AZT.

Egron D, Arzumanov AA, Dyatkina NB, Aubertin AM, Imbach JL, Gosselin G, Krayevsky A, Périgaud C.

Bioorg Chem. 2001 Dec;29(6):333-44.

PMID:
11846432
18.

SATE (aryl) phosphotriester series. I. Synthesis and biological evaluation.

Peyrottes S, Gosselin G, Aubertin AM, Périgaud C.

Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):903-5.

PMID:
14565307
19.

Synthesis and anti-retroviral activity of O,O'-bis(3'-azido-2',3'-dideoxythymidin-5'-yl) phosphoramidate derivatives.

Kers I, Stawiński J, Girardet JL, Imbach JL, Périgaud C, Gosselin G, Aubertin AM.

Nucleosides Nucleotides. 1999 Oct;18(10):2317-25.

PMID:
10616733
20.

S-Acyl-2-thioethyl aryl phosphotriester derivatives as mononucleotide prodrugs.

Schlienger N, Peyrottes S, Kassem T, Imbach JL, Gosselin G, Aubertin AM, Périgaud C.

J Med Chem. 2000 Nov 16;43(23):4570-4.

PMID:
11087582

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