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Items: 1 to 20 of 91

1.

BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism.

Patke A, Mecklenbräuker I, Erdjument-Bromage H, Tempst P, Tarakhovsky A.

J Exp Med. 2006 Oct 30;203(11):2551-62. Epub 2006 Oct 23.

2.

BAFF activates Erk1/2 promoting cell proliferation and survival by Ca2+-CaMKII-dependent inhibition of PP2A in normal and neoplastic B-lymphoid cells.

Liang D, Zeng Q, Xu Z, Zhang H, Gui L, Xu C, Chen S, Zhang S, Huang S, Chen L.

Biochem Pharmacol. 2014 Jan 15;87(2):332-43. doi: 10.1016/j.bcp.2013.11.006. Epub 2013 Nov 22.

3.

The BAFF/APRIL system: emerging functions beyond B cell biology and autoimmunity.

Vincent FB, Saulep-Easton D, Figgett WA, Fairfax KA, Mackay F.

Cytokine Growth Factor Rev. 2013 Jun;24(3):203-15. doi: 10.1016/j.cytogfr.2013.04.003. Epub 2013 May 15. Review.

PMID:
23684423
4.

BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells.

Otipoby KL, Sasaki Y, Schmidt-Supprian M, Patke A, Gareus R, Pasparakis M, Tarakhovsky A, Rajewsky K.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12435-8. doi: 10.1073/pnas.0805460105. Epub 2008 Aug 19.

5.

Critical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.

Yu M, Chen Y, He Y, Podd A, Fu G, Wright JA, Kleiman E, Khan WN, Wen R, Wang D.

J Immunol. 2012 Dec 1;189(11):5185-93. doi: 10.4049/jimmunol.1102952. Epub 2012 Oct 19.

6.

Rapamycin inhibits BAFF-stimulated cell proliferation and survival by suppressing mTOR-mediated PP2A-Erk1/2 signaling pathway in normal and neoplastic B-lymphoid cells.

Zeng Q, Zhang H, Qin J, Xu Z, Gui L, Liu B, Liu C, Xu C, Liu W, Zhang S, Huang S, Chen L.

Cell Mol Life Sci. 2015 Dec;72(24):4867-84. doi: 10.1007/s00018-015-1976-1. Epub 2015 Jun 29.

PMID:
26118661
7.

B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling.

Mackay F, Silveira PA, Brink R.

Curr Opin Immunol. 2007 Jun;19(3):327-36. Epub 2007 Apr 12. Review.

PMID:
17433868
8.

Regulation of B-cell survival by BAFF-dependent PKCdelta-mediated nuclear signalling.

Mecklenbräuker I, Kalled SL, Leitges M, Mackay F, Tarakhovsky A.

Nature. 2004 Sep 23;431(7007):456-61. Epub 2004 Sep 8.

PMID:
15361883
9.

Bruton's tyrosine kinase mediates NF-kappa B activation and B cell survival by B cell-activating factor receptor of the TNF-R family.

Shinners NP, Carlesso G, Castro I, Hoek KL, Corn RA, Woodland RT, Scott ML, Wang D, Khan WN.

J Immunol. 2007 Sep 15;179(6):3872-80. Erratum in: J Immunol. 2007 Nov 1;179(9):6369. Woodland, Robert L [corrected to Woodland, Robert T].

10.

Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.

Woodland RT, Fox CJ, Schmidt MR, Hammerman PS, Opferman JT, Korsmeyer SJ, Hilbert DM, Thompson CB.

Blood. 2008 Jan 15;111(2):750-60. Epub 2007 Oct 17.

11.

BAFF and the regulation of B cell survival.

Schneider P, Tschopp J.

Immunol Lett. 2003 Jul 3;88(1):57-62. Review.

PMID:
12853163
12.

BAFF and APRIL support chronic lymphocytic leukemia B-cell survival through activation of the canonical NF-kappaB pathway.

Endo T, Nishio M, Enzler T, Cottam HB, Fukuda T, James DF, Karin M, Kipps TJ.

Blood. 2007 Jan 15;109(2):703-10. Epub 2006 Sep 14.

13.

Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells.

Gorelik L, Gilbride K, Dobles M, Kalled SL, Zandman D, Scott ML.

J Exp Med. 2003 Sep 15;198(6):937-45.

14.

In vitro and in vivo activation induces BAFF and APRIL expression in B cells.

Chu VT, Enghard P, Riemekasten G, Berek C.

J Immunol. 2007 Nov 1;179(9):5947-57.

15.

Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL.

Benson MJ, Dillon SR, Castigli E, Geha RS, Xu S, Lam KP, Noelle RJ.

J Immunol. 2008 Mar 15;180(6):3655-9.

16.

B-cell activating factor (BAFF) plays a role in the mechanism of action of a tolerogenic peptide that ameliorates lupus.

Parameswaran R, Ben David H, Sharabi A, Zinger H, Mozes E.

Clin Immunol. 2009 May;131(2):223-32. doi: 10.1016/j.clim.2008.12.009. Epub 2009 Feb 1.

PMID:
19188092
17.

Reverse signaling through BAFF differentially regulates the expression of inflammatory mediators and cytoskeletal movements in THP-1 cells.

Jeon ST, Kim WJ, Lee SM, Lee MY, Park SB, Lee SH, Kim IS, Suk K, Choi BK, Choi EM, Kwon BS, Lee WH.

Immunol Cell Biol. 2010 Feb;88(2):148-56. doi: 10.1038/icb.2009.75. Epub 2009 Oct 20.

PMID:
19841639
18.

BAFF selectively enhances the survival of plasmablasts generated from human memory B cells.

Avery DT, Kalled SL, Ellyard JI, Ambrose C, Bixler SA, Thien M, Brink R, Mackay F, Hodgkin PD, Tangye SG.

J Clin Invest. 2003 Jul;112(2):286-97. Erratum in: J Clin Invest. 2004 Apr;113(7):1069.

19.

Signaling by the tumor necrosis factor receptor superfamily in B-cell biology and disease.

Rickert RC, Jellusova J, Miletic AV.

Immunol Rev. 2011 Nov;244(1):115-33. doi: 10.1111/j.1600-065X.2011.01067.x. Review.

20.

B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells.

Ng LG, Sutherland AP, Newton R, Qian F, Cachero TG, Scott ML, Thompson JS, Wheway J, Chtanova T, Groom J, Sutton IJ, Xin C, Tangye SG, Kalled SL, Mackay F, Mackay CR.

J Immunol. 2004 Jul 15;173(2):807-17.

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