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Items: 1 to 20 of 111

1.

Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex.

Cooper MP, Qu L, Rohas LM, Lin J, Yang W, Erdjument-Bromage H, Tempst P, Spiegelman BM.

Genes Dev. 2006 Nov 1;20(21):2996-3009. Epub 2006 Oct 18.

2.

Role of PGC-1α in exercise and fasting-induced adaptations in mouse liver.

Haase TN, Ringholm S, Leick L, Biensø RS, Kiilerich K, Johansen S, Nielsen MM, Wojtaszewski JF, Hidalgo J, Pedersen PA, Pilegaard H.

Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1501-9. doi: 10.1152/ajpregu.00775.2010. Epub 2011 Aug 10.

4.

Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice.

Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY, Mootha VK, Jäger S, Vianna CR, Reznick RM, Cui L, Manieri M, Donovan MX, Wu Z, Cooper MP, Fan MC, Rohas LM, Zavacki AM, Cinti S, Shulman GI, Lowell BB, Krainc D, Spiegelman BM.

Cell. 2004 Oct 1;119(1):121-35.

5.

Modulation of PGC-1 coactivator pathways in brown fat differentiation through LRP130.

Cooper MP, Uldry M, Kajimura S, Arany Z, Spiegelman BM.

J Biol Chem. 2008 Nov 14;283(46):31960-7. doi: 10.1074/jbc.M805431200. Epub 2008 Aug 26.

6.

DNA damage induces down-regulation of PEPCK and G6P gene expression through degradation of PGC-1alpha.

Kim HJ, Jee HJ, Yun J.

Acta Biochim Biophys Sin (Shanghai). 2011 Aug;43(8):589-94. doi: 10.1093/abbs/gmr053. Epub 2011 Jul 5.

PMID:
21733854
7.

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.

Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P.

Nature. 2005 Mar 3;434(7029):113-8.

PMID:
15744310
8.

Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice.

Burgess SC, Leone TC, Wende AR, Croce MA, Chen Z, Sherry AD, Malloy CR, Finck BN.

J Biol Chem. 2006 Jul 14;281(28):19000-8. Epub 2006 May 2.

9.

Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity.

Liang H, Balas B, Tantiwong P, Dube J, Goodpaster BH, O'Doherty RM, DeFronzo RA, Richardson A, Musi N, Ward WF.

Am J Physiol Endocrinol Metab. 2009 Apr;296(4):E945-54. doi: 10.1152/ajpendo.90292.2008. Epub 2009 Feb 10.

10.

Increased phosphoenolpyruvate carboxykinase gene expression and steatosis during hepatitis C virus subgenome replication: role of nonstructural component 5A and CCAAT/enhancer-binding protein β.

Qadri I, Choudhury M, Rahman SM, Knotts TA, Janssen RC, Schaack J, Iwahashi M, Puljak L, Simon FR, Kilic G, Fitz JG, Friedman JE.

J Biol Chem. 2012 Oct 26;287(44):37340-51. doi: 10.1074/jbc.M112.384743. Epub 2012 Sep 6.

11.

The developmental regulation of peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression in the liver is partially dissociated from the control of gluconeogenesis and lipid catabolism.

Yubero P, Hondares E, Carmona MC, Rossell M, Gonzalez FJ, Iglesias R, Giralt M, Villarroya F.

Endocrinology. 2004 Sep;145(9):4268-77. Epub 2004 Jun 3.

PMID:
15178647
12.

Estrogen-related receptor alpha is a repressor of phosphoenolpyruvate carboxykinase gene transcription.

Herzog B, Cardenas J, Hall RK, Villena JA, Budge PJ, Giguère V, Granner DK, Kralli A.

J Biol Chem. 2006 Jan 6;281(1):99-106. Epub 2005 Nov 2.

13.

Metformin induces PGC-1α expression and selectively affects hepatic PGC-1α functions.

Aatsinki SM, Buler M, Salomäki H, Koulu M, Pavek P, Hakkola J.

Br J Pharmacol. 2014 May;171(9):2351-63. doi: 10.1111/bph.12585.

14.

Control of gluconeogenic genes during intense/prolonged exercise: hormone-independent effect of muscle-derived IL-6 on hepatic tissue and PEPCK mRNA.

Banzet S, Koulmann N, Simler N, Sanchez H, Chapot R, Serrurier B, Peinnequin A, Bigard X.

J Appl Physiol (1985). 2009 Dec;107(6):1830-9. doi: 10.1152/japplphysiol.00739.2009. Epub 2009 Oct 22.

15.

Forkhead Box P1 (FOXP1) Transcription Factor Regulates Hepatic Glucose Homeostasis.

Zou Y, Gong N, Cui Y, Wang X, Cui A, Chen Q, Jiao T, Dong X, Yang H, Zhang S, Fang F, Chang Y.

J Biol Chem. 2015 Dec 18;290(51):30607-15. doi: 10.1074/jbc.M115.681627. Epub 2015 Oct 26.

16.

CITED2 links hormonal signaling to PGC-1α acetylation in the regulation of gluconeogenesis.

Sakai M, Matsumoto M, Tujimura T, Yongheng C, Noguchi T, Inagaki K, Inoue H, Hosooka T, Takazawa K, Kido Y, Yasuda K, Hiramatsu R, Matsuki Y, Kasuga M.

Nat Med. 2012 Mar 18;18(4):612-7. doi: 10.1038/nm.2691.

PMID:
22426420
17.

Gly482Ser mutation impairs the effects of peroxisome proliferator-activated receptor γ coactivator-1α on decreasing fat deposition and stimulating phosphoenolpyruvate carboxykinase expression in hepatocytes.

Chen Y, Mu P, He S, Tang X, Guo X, Li H, Xu H, Woo SL, Qian X, Zeng L, Wu C.

Nutr Res. 2013 Apr;33(4):332-9. doi: 10.1016/j.nutres.2013.02.003. Epub 2013 Mar 9.

PMID:
23602251
18.

CCAAT/enhancer binding protein-beta is a transcriptional regulator of peroxisome-proliferator-activated receptor-gamma coactivator-1alpha in the regenerating liver.

Wang H, Peiris TH, Mowery A, Le Lay J, Gao Y, Greenbaum LE.

Mol Endocrinol. 2008 Jul;22(7):1596-605. doi: 10.1210/me.2007-0388. Epub 2008 May 8.

19.

p38 Mitogen-activated protein kinase mediates free fatty acid-induced gluconeogenesis in hepatocytes.

Collins QF, Xiong Y, Lupo EG Jr, Liu HY, Cao W.

J Biol Chem. 2006 Aug 25;281(34):24336-44. Epub 2006 Jun 27.

20.

Sensitivity of lipid metabolism and insulin signaling to genetic alterations in hepatic peroxisome proliferator-activated receptor-gamma coactivator-1alpha expression.

Estall JL, Kahn M, Cooper MP, Fisher FM, Wu MK, Laznik D, Qu L, Cohen DE, Shulman GI, Spiegelman BM.

Diabetes. 2009 Jul;58(7):1499-508. doi: 10.2337/db08-1571. Epub 2009 Apr 14.

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