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Items: 1 to 20 of 96

1.

The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging.

Dumble M, Moore L, Chambers SM, Geiger H, Van Zant G, Goodell MA, Donehower LA.

Blood. 2007 Feb 15;109(4):1736-42. Epub 2006 Oct 10.

2.

Tumor suppressor dosage regulates stem cell dynamics during aging.

Gatza C, Moore L, Dumble M, Donehower LA.

Cell Cycle. 2007 Jan 1;6(1):52-5. Epub 2007 Jan 4. Review.

PMID:
17245110
3.

Insights into aging obtained from p53 mutant mouse models.

Dumble M, Gatza C, Tyner S, Venkatachalam S, Donehower LA.

Ann N Y Acad Sci. 2004 Jun;1019:171-7. Review.

PMID:
15247009
4.

Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells.

Asai T, Liu Y, Di Giandomenico S, Bae N, Ndiaye-Lobry D, Deblasio A, Menendez S, Antipin Y, Reva B, Wevrick R, Nimer SD.

Blood. 2012 Aug 23;120(8):1601-12. doi: 10.1182/blood-2011-11-393983. Epub 2012 Jul 9.

5.

Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice.

TeKippe M, Harrison DE, Chen J.

Exp Hematol. 2003 Jun;31(6):521-7.

PMID:
12829028
6.

Serial transplantation of p53-deficient hemopoietic progenitor cells to assess their infinite growth potential.

Hirabayashi Y, Matsuda M, Aizawa S, Kodama Y, Kanno J, Inoue T.

Exp Biol Med (Maywood). 2002 Jul;227(7):474-9.

PMID:
12094011
7.

Wip1 deficiency impairs haematopoietic stem cell function via p53 and mTORC1 pathways.

Chen Z, Yi W, Morita Y, Wang H, Cong Y, Liu JP, Xiao Z, Rudolph KL, Cheng T, Ju Z.

Nat Commun. 2015 Apr 16;6:6808. doi: 10.1038/ncomms7808.

PMID:
25879755
8.

A small molecule inhibitor of p53 stimulates amplification of hematopoietic stem cells but does not promote tumor development in mice.

Leonova KI, Shneyder J, Antoch MP, Toshkov IA, Novototskaya LR, Komarov PG, Komarova EA, Gudkov AV.

Cell Cycle. 2010 Apr 1;9(7):1434-43. Epub 2010 Apr 1.

9.

p53 regulates hematopoietic stem cell quiescence.

Liu Y, Elf SE, Miyata Y, Sashida G, Liu Y, Huang G, Di Giandomenico S, Lee JM, Deblasio A, Menendez S, Antipin J, Reva B, Koff A, Nimer SD.

Cell Stem Cell. 2009 Jan 9;4(1):37-48. doi: 10.1016/j.stem.2008.11.006.

10.

Smurf2 regulates hematopoietic stem cell self-renewal and aging.

Ramkumar C, Kong Y, Trabucco SE, Gerstein RM, Zhang H.

Aging Cell. 2014 Jun;13(3):478-86. doi: 10.1111/acel.12195. Epub 2014 Feb 4.

11.

TXNIP maintains the hematopoietic cell pool by switching the function of p53 under oxidative stress.

Jung H, Kim MJ, Kim DO, Kim WS, Yoon SJ, Park YJ, Yoon SR, Kim TD, Suh HW, Yun S, Min JK, Lee HG, Lee YH, Na HJ, Lee DC, Kim HC, Choi I.

Cell Metab. 2013 Jul 2;18(1):75-85. doi: 10.1016/j.cmet.2013.06.002.

12.

Role of p53 in hematopoietic recovery after cytotoxic treatment.

Wlodarski P, Wasik M, Ratajczak MZ, Sevignani C, Hoser G, Kawiak J, Gewirtz AM, Calabretta B, Skorski T.

Blood. 1998 Apr 15;91(8):2998-3006.

13.

Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem cell exhaustion and development of a myeloproliferative disorder in aging mice.

Singh KP, Bennett JA, Casado FL, Walrath JL, Welle SL, Gasiewicz TA.

Stem Cells Dev. 2014 Jan 15;23(2):95-106. doi: 10.1089/scd.2013.0346. Epub 2013 Oct 19.

14.

[Effect of Angelica sinensis polysaccharide on expression of telomere, telomerase and P53 in mice aging hematopoietic stem cells].

Zhang XP, Liu J, Xu CY, Wei Q, Li J, Wang L, Wang JW, Wang YP.

Zhongguo Zhong Yao Za Zhi. 2013 Jul;38(14):2354-8. Chinese.

PMID:
24199571
15.

Pim1 serine/threonine kinase regulates the number and functions of murine hematopoietic stem cells.

An N, Lin YW, Mahajan S, Kellner JN, Wang Y, Li Z, Kraft AS, Kang Y.

Stem Cells. 2013 Jun;31(6):1202-12. doi: 10.1002/stem.1369.

16.

Cdc42 and aging of hematopoietic stem cells.

Geiger H, Zheng Y.

Curr Opin Hematol. 2013 Jul;20(4):295-300. doi: 10.1097/MOH.0b013e3283615aba. Review.

17.

p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency.

Belle JI, Langlais D, Petrov JC, Pardo M, Jones RG, Gros P, Nijnik A.

Blood. 2015 Apr 9;125(15):2344-8. doi: 10.1182/blood-2014-05-574111. Epub 2015 Feb 20.

18.

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion.

Beerman I, Bhattacharya D, Zandi S, Sigvardsson M, Weissman IL, Bryder D, Rossi DJ.

Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5465-70. doi: 10.1073/pnas.1000834107. Epub 2010 Mar 18.

19.

Quantification of self-renewal capacity in single hematopoietic stem cells from normal and Lnk-deficient mice.

Ema H, Sudo K, Seita J, Matsubara A, Morita Y, Osawa M, Takatsu K, Takaki S, Nakauchi H.

Dev Cell. 2005 Jun;8(6):907-14.

20.

Hematopoietic stem cell and progenitor defects in Sca-1/Ly-6A-null mice.

Ito CY, Li CY, Bernstein A, Dick JE, Stanford WL.

Blood. 2003 Jan 15;101(2):517-23. Epub 2002 Aug 29.

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