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Items: 1 to 20 of 52

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Modulation of the hepatic malonyl-CoA-carnitine palmitoyltransferase 1A partnership creates a metabolic switch allowing oxidation of de novo fatty acids.

Akkaoui M, Cohen I, Esnous C, Lenoir V, Sournac M, Girard J, Prip-Buus C.

Biochem J. 2009 May 27;420(3):429-38. doi: 10.1042/BJ20081932.

PMID:
19302064
3.

Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer.

Shao H, Mohamed EM, Xu GG, Waters M, Jing K, Ma Y, Zhang Y, Spiegel S, Idowu MO, Fang X.

Oncotarget. 2016 Jan 26;7(4):3832-46. doi: 10.18632/oncotarget.6757.

4.

A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels.

Stefanovic-Racic M, Perdomo G, Mantell BS, Sipula IJ, Brown NF, O'Doherty RM.

Am J Physiol Endocrinol Metab. 2008 May;294(5):E969-77. doi: 10.1152/ajpendo.00497.2007. Epub 2008 Mar 18.

5.

Carbacyclin induces carnitine palmitoyltransferase-1 in cardiomyocytes via peroxisome proliferator-activated receptor (PPAR) delta independent of the IP receptor signaling pathway.

Kuroda T, Hirota H, Fujio Y, Sugiyama S, Masaki M, Hiramoto Y, Shioyama W, Okamoto K, Hori M, Yamauchi-Takihara K.

J Mol Cell Cardiol. 2007 Jul;43(1):54-62. Epub 2007 Apr 12.

PMID:
17540403
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Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production.

Obici S, Feng Z, Arduini A, Conti R, Rossetti L.

Nat Med. 2003 Jun;9(6):756-61. Epub 2003 May 18.

PMID:
12754501
8.

Fibroblast growth factor 2-induced cytoplasmic asparaginyl-tRNA synthetase promotes survival of osteoblasts by regulating anti-apoptotic PI3K/Akt signaling.

Park SJ, Kim SH, Choi HS, Rhee Y, Lim SK.

Bone. 2009 Nov;45(5):994-1003. doi: 10.1016/j.bone.2009.07.018. Epub 2009 Jul 23.

PMID:
19631775
9.

Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats.

Pocai A, Lam TK, Obici S, Gutierrez-Juarez R, Muse ED, Arduini A, Rossetti L.

J Clin Invest. 2006 Apr;116(4):1081-91. Epub 2006 Mar 9.

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IGF-I mediates regeneration of endocrine pancreas by increasing beta cell replication through cell cycle protein modulation in mice.

Agudo J, Ayuso E, Jimenez V, Salavert A, Casellas A, Tafuro S, Haurigot V, Ruberte J, Segovia JC, Bueren J, Bosch F.

Diabetologia. 2008 Oct;51(10):1862-72. doi: 10.1007/s00125-008-1087-8. Epub 2008 Jul 29.

PMID:
18663428
12.

Mutations in the catalytic subunit of class IA PI3K confer leukemogenic potential to hematopoietic cells.

Horn S, Bergholz U, Jücker M, McCubrey JA, Trümper L, Stocking C, Bäsecke J.

Oncogene. 2008 Jul 3;27(29):4096-106. doi: 10.1038/onc.2008.40. Epub 2008 Mar 3.

PMID:
18317450
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Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity.

Guo W, Pirtskhalava T, Tchkonia T, Xie W, Thomou T, Han J, Wang T, Wong S, Cartwright A, Hegardt FG, Corkey BE, Kirkland JL.

Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1041-51. Epub 2006 Dec 5.

15.

Amyloid beta-derived neuroplasticity in bone marrow-derived mesenchymal stem cells is mediated by NPY and 5-HT2B receptors via ERK1/2 signalling pathways.

Jin HK, Bae JS, Furuya S, Carter JE.

Cell Prolif. 2009 Oct;42(5):571-86. doi: 10.1111/j.1365-2184.2009.00625.x. Epub 2009 Jul 13.

PMID:
19614678
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c-Src is required for tropomyosin receptor kinase C (TrkC)-induced activation of the phosphatidylinositol 3-kinase (PI3K)-AKT pathway.

Jin W, Yun C, Jeong J, Park Y, Lee HD, Kim SJ.

J Biol Chem. 2008 Jan 18;283(3):1391-400. Epub 2007 Nov 8.

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