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Items: 1 to 20 of 178

1.

Attenuation of phagocytosis of xenogeneic cells by manipulating CD47.

Wang H, VerHalen J, Madariaga ML, Xiang S, Wang S, Lan P, Oldenborg PA, Sykes M, Yang YG.

Blood. 2007 Jan 15;109(2):836-42. Epub 2006 Sep 28.

2.

Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages.

Ide K, Wang H, Tahara H, Liu J, Wang X, Asahara T, Sykes M, Yang YG, Ohdan H.

Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5062-6. Epub 2007 Mar 12.

3.

Expression of recipient CD47 on rat insulinoma cell xenografts prevents macrophage-mediated rejection through SIRPα inhibitory signaling in mice.

Teraoka Y, Ide K, Morimoto H, Tahara H, Ohdan H.

PLoS One. 2013;8(3):e58359. doi: 10.1371/journal.pone.0058359. Epub 2013 Mar 5.

4.

Human CD47 expression permits survival of porcine cells in immunodeficient mice that express SIRPα capable of binding to human CD47.

Wang C, Wang H, Ide K, Wang Y, Van Rooijen N, Ohdan H, Yang YG.

Cell Transplant. 2011;20(11-12):1915-20. doi: 10.3727/096368911X566253. Epub 2011 Apr 29.

5.

Self inhibition of phagocytosis: the affinity of 'marker of self' CD47 for SIRPalpha dictates potency of inhibition but only at low expression levels.

Tsai RK, Rodriguez PL, Discher DE.

Blood Cells Mol Dis. 2010 Jun 15;45(1):67-74. doi: 10.1016/j.bcmd.2010.02.016. Epub 2010 Mar 17.

6.
7.

Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes.

Gitik M, Liraz-Zaltsman S, Oldenborg PA, Reichert F, Rotshenker S.

J Neuroinflammation. 2011 Mar 15;8:24. doi: 10.1186/1742-2094-8-24.

8.

CD47 is required for suppression of allograft rejection by donor-specific transfusion.

Wang H, Wu X, Wang Y, Oldenborg PA, Yang YG.

J Immunol. 2010 Apr 1;184(7):3401-7. doi: 10.4049/jimmunol.0901550. Epub 2010 Mar 5.

9.

The BALB/c-specific polymorphic SIRPA enhances its affinity for human CD47, inhibiting phagocytosis against human cells to promote xenogeneic engraftment.

Iwamoto C, Takenaka K, Urata S, Yamauchi T, Shima T, Kuriyama T, Daitoku S, Saito Y, Miyamoto T, Iwasaki H, Kitabayashi I, Itoh K, Kishimoto J, Kohda D, Matozaki T, Akashi K.

Exp Hematol. 2014 Mar;42(3):163-171.e1. doi: 10.1016/j.exphem.2013.11.005. Epub 2013 Nov 20.

PMID:
24269920
10.

Transgenic expression of human CD47 markedly increases engraftment in a murine model of pig-to-human hematopoietic cell transplantation.

Tena A, Kurtz J, Leonard DA, Dobrinsky JR, Terlouw SL, Mtango N, Verstegen J, Germana S, Mallard C, Arn JS, Sachs DH, Hawley RJ.

Am J Transplant. 2014 Dec;14(12):2713-22. doi: 10.1111/ajt.12918. Epub 2014 Oct 2. Erratum in: Am J Transplant. 2015 Jan;15(1):289.

11.

Loss of Cell Surface CD47 Clustering Formation and Binding Avidity to SIRPα Facilitate Apoptotic Cell Clearance by Macrophages.

Lv Z, Bian Z, Shi L, Niu S, Ha B, Tremblay A, Li L, Zhang X, Paluszynski J, Liu M, Zen K, Liu Y.

J Immunol. 2015 Jul 15;195(2):661-71. doi: 10.4049/jimmunol.1401719. Epub 2015 Jun 17.

12.

CD47: a new player in phagocytosis and xenograft rejection.

Navarro-Alvarez N, Yang YG.

Cell Mol Immunol. 2011 Jul;8(4):285-8. doi: 10.1038/cmi.2010.83. Epub 2011 Jan 24. Review.

13.

The CD47-SIRPα signalling system: its physiological roles and therapeutic application.

Murata Y, Kotani T, Ohnishi H, Matozaki T.

J Biochem. 2014 Jun;155(6):335-44. doi: 10.1093/jb/mvu017. Epub 2014 Mar 12. Review.

PMID:
24627525
14.
15.

Enhanced phagocytosis of CD47-deficient red blood cells by splenic macrophages requires SHPS-1.

Ishikawa-Sekigami T, Kaneko Y, Saito Y, Murata Y, Okazawa H, Ohnishi H, Oldenborg PA, Nojima Y, Matozaki T.

Biochem Biophys Res Commun. 2006 May 19;343(4):1197-200. Epub 2006 Mar 24.

PMID:
16580635
16.

Lack of CD47 impairs bone cell differentiation and results in an osteopenic phenotype in vivo due to impaired signal regulatory protein α (SIRPα) signaling.

Koskinen C, Persson E, Baldock P, Stenberg Å, Boström I, Matozaki T, Oldenborg PA, Lundberg P.

J Biol Chem. 2013 Oct 11;288(41):29333-44. doi: 10.1074/jbc.M113.494591. Epub 2013 Aug 29.

17.

Ectopic expression of murine CD47 minimizes macrophage rejection of human hepatocyte xenografts in immunodeficient mice.

Waern JM, Yuan Q, Rüdrich U, Becker PD, Schulze K, Strick-Marchand H, Huntington ND, Zacher BJ, Wursthorn K, DiSanto JP, Guzman CA, Manns MP, Ott M, Bock M.

Hepatology. 2012 Oct;56(4):1479-88. doi: 10.1002/hep.25816.

PMID:
22535707
18.

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts.

Theocharides AP, Jin L, Cheng PY, Prasolava TK, Malko AV, Ho JM, Poeppl AG, van Rooijen N, Minden MD, Danska JS, Dick JE, Wang JC.

J Exp Med. 2012 Sep 24;209(10):1883-99. Epub 2012 Sep 3.

19.

Soluble extracellular domains of human SIRPα and CD47 expressed in Escherichia coli enhances the phagocytosis of leukemia cells by macrophages in vitro.

Lin Y, Yan XQ, Yang F, Yang XW, Jiang X, Zhao XC, Zhu BK, Liu L, Qin HY, Liang YM, Han H.

Protein Expr Purif. 2012 Sep;85(1):109-16. doi: 10.1016/j.pep.2012.07.002. Epub 2012 Jul 17.

PMID:
22813925
20.

Dose-dependent inhibitory effect of CD47 in macrophage uptake of IgG-opsonized murine erythrocytes.

Olsson M, Nilsson A, Oldenborg PA.

Biochem Biophys Res Commun. 2007 Jan 5;352(1):193-7. Epub 2006 Nov 10.

PMID:
17112468

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