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Items: 1 to 20 of 390

1.

Relationships between biomarkers of exposure and toxicokinetics in Fischer 344 rats and B6C3F1 mice administered single doses of acrylamide and glycidamide and multiple doses of acrylamide.

Tareke E, Twaddle NC, McDaniel LP, Churchwell MI, Young JF, Doerge DR.

Toxicol Appl Pharmacol. 2006 Nov 15;217(1):63-75. Epub 2006 Aug 15.

PMID:
17007897
2.

Urinary excretion of acrylamide and metabolites in Fischer 344 rats and B6C3F(1) mice administered a single dose of acrylamide.

Doerge DR, Twaddle NC, Boettcher MI, McDaniel LP, Angerer J.

Toxicol Lett. 2007 Feb 28;169(1):34-42. Epub 2006 Dec 16.

PMID:
17224249
3.

Toxicokinetics of acrylamide and glycidamide in Fischer 344 rats.

Doerge DR, Young JF, McDaniel LP, Twaddle NC, Churchwell MI.

Toxicol Appl Pharmacol. 2005 Nov 1;208(3):199-209.

PMID:
16239164
4.

Toxicokinetics of acrylamide and glycidamide in B6C3F1 mice.

Doerge DR, Young JF, McDaniel LP, Twaddle NC, Churchwell MI.

Toxicol Appl Pharmacol. 2005 Feb 1;202(3):258-67.

PMID:
15667831
5.

DNA adduct formation from acrylamide via conversion to glycidamide in adult and neonatal mice.

Gamboa da Costa G, Churchwell MI, Hamilton LP, Von Tungeln LS, Beland FA, Marques MM, Doerge DR.

Chem Res Toxicol. 2003 Oct;16(10):1328-37.

PMID:
14565774
6.

Determination of acrylamide and glycidamide serum toxicokinetics in B6C3F1 mice using LC-ES/MS/MS.

Twaddle NC, McDaniel LP, Gamboa da Costa G, Churchwell MI, Beland FA, Doerge DR.

Cancer Lett. 2004 Apr 15;207(1):9-17.

PMID:
15050729
7.

DNA adducts derived from administration of acrylamide and glycidamide to mice and rats.

Doerge DR, Gamboa da Costa G, McDaniel LP, Churchwell MI, Twaddle NC, Beland FA.

Mutat Res. 2005 Feb 7;580(1-2):131-41.

PMID:
15668115
8.

Induction of micronuclei in mouse and rat by glycidamide, genotoxic metabolite of acrylamide.

Paulsson B, Kotova N, Grawé J, Henderson A, Granath F, Golding B, Törnqvist M.

Mutat Res. 2003 Feb 5;535(1):15-24.

PMID:
12547279
9.

Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts.

Ghanayem BI, McDaniel LP, Churchwell MI, Twaddle NC, Snyder R, Fennell TR, Doerge DR.

Toxicol Sci. 2005 Dec;88(2):311-8. Epub 2005 Sep 1.

10.

Hemoglobin adducts and micronucleus frequencies in mouse and rat after acrylamide or N-methylolacrylamide treatment.

Paulsson B, Grawé J, Törnqvist M.

Mutat Res. 2002 Apr 26;516(1-2):101-11.

PMID:
11943616
11.

Physiologically based pharmacokinetic/pharmacodynamic model for acrylamide and its metabolites in mice, rats, and humans.

Young JF, Luecke RH, Doerge DR.

Chem Res Toxicol. 2007 Mar;20(3):388-99. Epub 2007 Feb 27.

PMID:
17323977
12.

Development of a physiologically-based toxicokinetic model of acrylamide and glycidamide in rats and humans.

Sweeney LM, Kirman CR, Gargas ML, Carson ML, Tardiff RG.

Food Chem Toxicol. 2010 Feb;48(2):668-85. doi: 10.1016/j.fct.2009.11.049. Epub 2009 Dec 3.

PMID:
19948202
13.

Genotoxic effects of acrylamide and glycidamide in mouse lymphoma cells.

Mei N, Hu J, Churchwell MI, Guo L, Moore MM, Doerge DR, Chen T.

Food Chem Toxicol. 2008 Feb;46(2):628-36. Epub 2007 Sep 22.

PMID:
18029077
14.

Comparison of estimated dietary intake of acrylamide with hemoglobin adducts of acrylamide and glycidamide.

Bjellaas T, Olesen PT, Frandsen H, Haugen M, Stølen LH, Paulsen JE, Alexander J, Lundanes E, Becher G.

Toxicol Sci. 2007 Jul;98(1):110-7. Epub 2007 Apr 21.

15.

Genotoxicity of acrylamide and its metabolite glycidamide administered in drinking water to male and female Big Blue mice.

Manjanatha MG, Aidoo A, Shelton SD, Bishop ME, McDaniel LP, Lyn-Cook LE, Doerge DR.

Environ Mol Mutagen. 2006 Jan;47(1):6-17.

PMID:
15957192
16.

Acrylamide and glycidamide: approach towards risk assessment based on biomarker guided dosimetry of genotoxic/mutagenic effects in human blood.

Baum M, Fauth E, Fritzen S, Herrmann A, Mertes P, Rudolphi M, Spormann T, Zankl H, Eisenbrand G, Bertow D.

Adv Exp Med Biol. 2005;561:77-88.

PMID:
16438290
17.

Mercapturic acids of acrylamide and glycidamide as biomarkers of the internal exposure to acrylamide in the general population.

Boettcher MI, Schettgen T, Kütting B, Pischetsrieder M, Angerer J.

Mutat Res. 2005 Feb 7;580(1-2):167-76.

PMID:
15668118
18.

Autoclave sterilization produces acrylamide in rodent diets: implications for toxicity testing.

Twaddle NC, Churchwell MI, McDaniel LP, Doerge DR.

J Agric Food Chem. 2004 Jun 30;52(13):4344-9.

PMID:
15212490
19.

DNA damage and DNA adduct formation in rat tissues following oral administration of acrylamide.

Manière I, Godard T, Doerge DR, Churchwell MI, Guffroy M, Laurentie M, Poul JM.

Mutat Res. 2005 Feb 7;580(1-2):119-29.

PMID:
15668114
20.

Cytogenetic damage induced by acrylamide and glycidamide in mammalian cells: correlation with specific glycidamide-DNA adducts.

Martins C, Oliveira NG, Pingarilho M, Gamboa da Costa G, Martins V, Marques MM, Beland FA, Churchwell MI, Doerge DR, Rueff J, Gaspar JF.

Toxicol Sci. 2007 Feb;95(2):383-90. Epub 2006 Nov 6.

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