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Thrombin induces GPIb-IX-mediated fibrin binding to alphaIIbbeta3 in a reconstituted Chinese hamster ovary cell model.

Pabón D, Jayo A, Xie J, Lastres P, González-Manchón C.

J Thromb Haemost. 2006 Oct;4(10):2238-47.


Glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3): effects of receptor clustering and von Willebrand factor adhesion.

Arya M, López JA, Romo GM, Cruz MA, Kasirer-Friede A, Shattil SJ, Anvari B.

J Thromb Haemost. 2003 Jun;1(6):1150-7.


Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin alpha IIbbeta 3. Studies in human platelets ans transfected Chinese hamster ovary cells.

Yap CL, Hughan SC, Cranmer SL, Nesbitt WS, Rooney MM, Giuliano S, Kulkarni S, Dopheide SM, Yuan Y, Salem HH, Jackson SP.

J Biol Chem. 2000 Dec 29;275(52):41377-88.


Cytoplasmic domains of GpIbalpha and GpIbbeta regulate 14-3-3zeta binding to GpIb/IX/V.

Feng S, Christodoulides N, Reséndiz JC, Berndt MC, Kroll MH.

Blood. 2000 Jan 15;95(2):551-7.


The von Willebrand factor-glycoprotein Ib/V/IX interaction induces actin polymerization and cytoskeletal reorganization in rolling platelets and glycoprotein Ib/V/IX-transfected cells.

Yuan Y, Kulkarni S, Ulsemer P, Cranmer SL, Yap CL, Nesbitt WS, Harper I, Mistry N, Dopheide SM, Hughan SC, Williamson D, de la Salle C, Salem HH, Lanza F, Jackson SP.

J Biol Chem. 1999 Dec 17;274(51):36241-51.


Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3.

Kasirer-Friede A, Ware J, Leng L, Marchese P, Ruggeri ZM, Shattil SJ.

J Biol Chem. 2002 Apr 5;277(14):11949-56. Epub 2002 Jan 25.


Inhibition of adhesive and signaling functions of the platelet GPIb-V-IX complex by a cell penetrating GPIbalpha peptide.

David T, Ohlmann P, Eckly A, Moog S, Cazenave JP, Gachet C, Lanza F.

J Thromb Haemost. 2006 Dec;4(12):2645-55. Erratum in: J Thromb Haemost. 2007 Jan;5(1):217.


Signaling through GP Ib-IX-V activates alpha IIb beta 3 independently of other receptors.

Kasirer-Friede A, Cozzi MR, Mazzucato M, De Marco L, Ruggeri ZM, Shattil SJ.

Blood. 2004 May 1;103(9):3403-11. Epub 2004 Jan 15.


Identification of five novel 14-3-3 isoforms interacting with the GPIb-IX complex in platelets.

Mangin PH, Receveur N, Wurtz V, David T, Gachet C, Lanza F.

J Thromb Haemost. 2009 Sep;7(9):1550-5. doi: 10.1111/j.1538-7836.2009.03530.x. Epub 2009 Jun 24.


Unique pathway of thrombin-induced platelet aggregation mediated by glycoprotein Ib.

Soslau G, Class R, Morgan DA, Foster C, Lord ST, Marchese P, Ruggeri ZM.

J Biol Chem. 2001 Jun 15;276(24):21173-83. Epub 2001 Mar 30.


Identification of a novel 14-3-3zeta binding site within the cytoplasmic domain of platelet glycoprotein Ibalpha that plays a key role in regulating the von Willebrand factor binding function of glycoprotein Ib-IX.

Yuan Y, Zhang W, Yan R, Liao Y, Zhao L, Ruan C, Du X, Dai K.

Circ Res. 2009 Dec 4;105(12):1177-85. doi: 10.1161/CIRCRESAHA.109.204669. Epub 2009 Oct 29.


Platelet aggregation: involvement of thrombin and fibrin(ogen).

Lisman T, Weeterings C, de Groot PG.

Front Biosci. 2005 Sep 1;10:2504-17. Review.


Distinct glycoprotein Ib/V/IX and integrin alpha IIbbeta 3-dependent calcium signals cooperatively regulate platelet adhesion under flow.

Nesbitt WS, Kulkarni S, Giuliano S, Goncalves I, Dopheide SM, Yap CL, Harper IS, Salem HH, Jackson SP.

J Biol Chem. 2002 Jan 25;277(4):2965-72. Epub 2001 Nov 16.


Functional association of phosphoinositide-3-kinase with platelet glycoprotein Ibalpha, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex.

Mu FT, Cranmer SL, Andrews RK, Berndt MC.

J Thromb Haemost. 2010 Feb;8(2):324-30. doi: 10.1111/j.1538-7836.2009.03672.x. Epub 2009 Oct 30.


Surface expression of glycoprotein ib alpha is dependent on glycoprotein ib beta: evidence from a novel mutation causing Bernard-Soulier syndrome.

Moran N, Morateck PA, Deering A, Ryan M, Montgomery RR, Fitzgerald DJ, Kenny D.

Blood. 2000 Jul 15;96(2):532-9.

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