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Items: 1 to 20 of 94

1.

Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor.

Wettschureck N, Lee E, Libutti SK, Offermanns S, Robey PG, Spiegel AM.

Mol Endocrinol. 2007 Jan;21(1):274-80. Epub 2006 Sep 20.

PMID:
16988000
2.

Calcium-sensing receptor expression and signalling in human parathyroid adenomas and primary hyperplasia.

Corbetta S, Mantovani G, Lania A, Borgato S, Vicentini L, Beretta E, Faglia G, Di Blasio AM, Spada A.

Clin Endocrinol (Oxf). 2000 Mar;52(3):339-48.

PMID:
10718832
3.

Parathyroid-specific interaction of the calcium-sensing receptor and G alpha q.

Pi M, Chen L, Huang M, Luo Q, Quarles LD.

Kidney Int. 2008 Dec;74(12):1548-56. doi: 10.1038/ki.2008.411. Epub 2008 Aug 27.

4.

Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.

Vogt S, Grosse R, Schultz G, Offermanns S.

J Biol Chem. 2003 Aug 1;278(31):28743-9. Epub 2003 May 27.

5.

The Gq/G11-mediated signaling pathway is critical for autocrine potentiation of insulin secretion in mice.

Sassmann A, Gier B, Gröne HJ, Drews G, Offermanns S, Wettschureck N.

J Clin Invest. 2010 Jun;120(6):2184-93. doi: 10.1172/JCI41541. Epub 2010 May 3.

6.

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.

Babinsky VN, Hannan FM, Gorvin CM, Howles SA, Nesbit MA, Rust N, Hanyaloglu AC, Hu J, Spiegel AM, Thakker RV.

J Biol Chem. 2016 May 13;291(20):10876-85. doi: 10.1074/jbc.M115.696401. Epub 2016 Mar 18.

7.

The calcium-sensing receptor is required for normal calcium homeostasis independent of parathyroid hormone.

Kos CH, Karaplis AC, Peng JB, Hediger MA, Goltzman D, Mohammad KS, Guise TA, Pollak MR.

J Clin Invest. 2003 Apr;111(7):1021-8.

8.

Relationship between parathyroid calcium-sensing receptor expression and potency of the calcimimetic, cinacalcet, in suppressing parathyroid hormone secretion in an in vivo murine model of primary hyperparathyroidism.

Kawata T, Imanishi Y, Kobayashi K, Kenko T, Wada M, Ishimura E, Miki T, Nagano N, Inaba M, Arnold A, Nishizawa Y.

Eur J Endocrinol. 2005 Oct;153(4):587-94.

10.

Pathophysiologic Changes in Extracellular pH Modulate Parathyroid Calcium-Sensing Receptor Activity and Secretion via a Histidine-Independent Mechanism.

Campion KL, McCormick WD, Warwicker J, Khayat ME, Atkinson-Dell R, Steward MC, Delbridge LW, Mun HC, Conigrave AD, Ward DT.

J Am Soc Nephrol. 2015 Sep;26(9):2163-71. doi: 10.1681/ASN.2014070653. Epub 2015 Jan 2.

11.

The G protein α subunit variant XLαs promotes inositol 1,4,5-trisphosphate signaling and mediates the renal actions of parathyroid hormone in vivo.

He Q, Zhu Y, Corbin BA, Plagge A, Bastepe M.

Sci Signal. 2015 Aug 25;8(391):ra84. doi: 10.1126/scisignal.aaa9953.

12.

Calcimimetic compound upregulates decreased calcium-sensing receptor expression level in parathyroid glands of rats with chronic renal insufficiency.

Mizobuchi M, Hatamura I, Ogata H, Saji F, Uda S, Shiizaki K, Sakaguchi T, Negi S, Kinugasa E, Koshikawa S, Akizawa T.

J Am Soc Nephrol. 2004 Oct;15(10):2579-87.

13.

Persistence of Ca2+-sensing receptor expression in functionally active, long-term human parathyroid cell cultures.

Roussanne MC, Gogusev J, Hory B, Duchambon P, Souberbielle JC, Nabarra B, Pierrat D, Sarfati E, Drüeke T, Bourdeau A.

J Bone Miner Res. 1998 Mar;13(3):354-62.

14.

The calcium sensing receptor: from understanding parathyroid calcium homeostasis to bone metastases.

Mihai R.

Ann R Coll Surg Engl. 2008 May;90(4):271-7. doi: 10.1308/003588408X286044.

15.

The calcium-sensing receptor is localized in caveolin-rich plasma membrane domains of bovine parathyroid cells.

Kifor O, Diaz R, Butters R, Kifor I, Brown EM.

J Biol Chem. 1998 Aug 21;273(34):21708-13.

16.

Calcimimetics with potent and selective activity on the parathyroid calcium receptor.

Nemeth EF, Steffey ME, Hammerland LG, Hung BC, Van Wagenen BC, DelMar EG, Balandrin MF.

Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):4040-5.

17.

Calcium-sensing receptor gene polymorphism affects the parathyroid response to moderate hypercalcemic suppression in patients with end-stage renal disease.

Yokoyama K, Shigematsu T, Tsukada T, Hara S, Yamada A, Kawaguchi Y, Hosoya T.

Clin Nephrol. 2002 Feb;57(2):131-5.

PMID:
11863123
18.

Parathyroid expression of calcium-sensing receptor protein and in vivo parathyroid hormone-Ca(2+) set-point in patients with primary hyperparathyroidism.

Cetani F, Picone A, Cerrai P, Vignali E, Borsari S, Pardi E, Viacava P, Naccarato AG, Miccoli P, Kifor O, Brown EM, Pinchera A, Marcocci C.

J Clin Endocrinol Metab. 2000 Dec;85(12):4789-94.

PMID:
11134144
19.

Calcium-sensing receptor and calcimimetic agents.

Coburn JW, Elangovan L, Goodman WG, Frazaõ JM.

Kidney Int Suppl. 1999 Dec;73:S52-8. Review.

PMID:
10633465
20.

Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells.

Mamillapalli R, VanHouten J, Zawalich W, Wysolmerski J.

J Biol Chem. 2008 Sep 5;283(36):24435-47. doi: 10.1074/jbc.M801738200. Epub 2008 Jul 11.

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