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Items: 1 to 20 of 222

1.

A membrane-targeted BID BCL-2 homology 3 peptide is sufficient for high potency activation of BAX in vitro.

Oh KJ, Barbuto S, Pitter K, Morash J, Walensky LD, Korsmeyer SJ.

J Biol Chem. 2006 Dec 1;281(48):36999-7008. Epub 2006 Sep 20.

2.

A stapled BID BH3 helix directly binds and activates BAX.

Walensky LD, Pitter K, Morash J, Oh KJ, Barbuto S, Fisher J, Smith E, Verdine GL, Korsmeyer SJ.

Mol Cell. 2006 Oct 20;24(2):199-210.

3.

tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formation.

Peng J, Tan C, Roberts GJ, Nikolaeva O, Zhang Z, Lapolla SM, Primorac S, Andrews DW, Lin J.

J Biol Chem. 2006 Nov 24;281(47):35802-11. Epub 2006 Sep 27.

4.

Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax.

Werner AB, de Vries E, Tait SW, Bontjer I, Borst J.

J Biol Chem. 2002 Jun 21;277(25):22781-8. Epub 2002 Apr 19.

5.

BH3-only protein bid participates in the Bcl-2 network in healthy liver cells.

Hikita H, Takehara T, Kodama T, Shimizu S, Hosui A, Miyagi T, Tatsumi T, Ishida H, Ohkawa K, Li W, Kanto T, Hiramatsu N, Hennighausen L, Yin XM, Hayashi N.

Hepatology. 2009 Dec;50(6):1972-80. doi: 10.1002/hep.23207.

6.

Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax.

Shamas-Din A, Bindner S, Chi X, Leber B, Andrews DW, Fradin C.

Biochem J. 2015 May 1;467(3):495-505. doi: 10.1042/BJ20141291.

PMID:
25714678
7.

BH3 domains other than Bim and Bid can directly activate Bax/Bak.

Du H, Wolf J, Schafer B, Moldoveanu T, Chipuk JE, Kuwana T.

J Biol Chem. 2011 Jan 7;286(1):491-501. doi: 10.1074/jbc.M110.167148. Epub 2010 Nov 1.

8.

BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes.

Terrones O, Etxebarria A, Landajuela A, Landeta O, Antonsson B, BasaƱez G.

J Biol Chem. 2008 Mar 21;283(12):7790-803. doi: 10.1074/jbc.M708814200. Epub 2008 Jan 14.

9.

The Bcl-2-associated death promoter (BAD) lowers the threshold at which the Bcl-2-interacting domain death agonist (BID) triggers mitochondria disintegration.

Howells CC, Baumann WT, Samuels DC, Finkielstein CV.

J Theor Biol. 2011 Feb 21;271(1):114-23. doi: 10.1016/j.jtbi.2010.11.040. Epub 2010 Dec 3.

PMID:
21130780
10.

Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.

Hockings C, Anwari K, Ninnis RL, Brouwer J, O'Hely M, Evangelista M, Hinds MG, Czabotar PE, Lee EF, Fairlie WD, Dewson G, Kluck RM.

Cell Death Dis. 2015 Apr 23;6:e1735. doi: 10.1038/cddis.2015.105.

11.

Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax.

Kim TH, Zhao Y, Barber MJ, Kuharsky DK, Yin XM.

J Biol Chem. 2000 Dec 15;275(50):39474-81.

12.

Bid: a Bax-like BH3 protein.

Billen LP, Shamas-Din A, Andrews DW.

Oncogene. 2008 Dec;27 Suppl 1:S93-104. doi: 10.1038/onc.2009.47. Review.

PMID:
19641510
13.

Mechanistic issues of the interaction of the hairpin-forming domain of tBid with mitochondrial cardiolipin.

Gonzalvez F, Pariselli F, Jalmar O, Dupaigne P, Sureau F, Dellinger M, Hendrickson EA, Bernard S, Petit PX.

PLoS One. 2010 Feb 22;5(2):e9342. doi: 10.1371/journal.pone.0009342.

14.

Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid.

Shamas-Din A, Satsoura D, Khan O, Zhu W, Leber B, Fradin C, Andrews DW.

Cell Death Dis. 2014 Jun 5;5:e1277. doi: 10.1038/cddis.2014.234.

15.

B cell lymphoma-2 (BCL-2) homology domain 3 (BH3) mimetics demonstrate differential activities dependent upon the functional repertoire of pro- and anti-apoptotic BCL-2 family proteins.

Renault TT, Elkholi R, Bharti A, Chipuk JE.

J Biol Chem. 2014 Sep 19;289(38):26481-91. doi: 10.1074/jbc.M114.569632. Epub 2014 Aug 5.

16.

Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.

Roucou X, Montessuit S, Antonsson B, Martinou JC.

Biochem J. 2002 Dec 15;368(Pt 3):915-21.

17.

Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak.

Zhai D, Luciano F, Zhu X, Guo B, Satterthwait AC, Reed JC.

J Biol Chem. 2005 Apr 22;280(16):15815-24. Epub 2005 Jan 20.

18.
19.

tBid undergoes multiple conformational changes at the membrane required for Bax activation.

Shamas-Din A, Bindner S, Zhu W, Zaltsman Y, Campbell C, Gross A, Leber B, Andrews DW, Fradin C.

J Biol Chem. 2013 Jul 26;288(30):22111-27. doi: 10.1074/jbc.M113.482109. Epub 2013 Jun 6.

20.

Examining BCL-2 family function with large unilamellar vesicles.

Asciolla JJ, Renault TT, Chipuk JE.

J Vis Exp. 2012 Oct 5;(68). pii: 4291. doi: 10.3791/4291.

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