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Items: 1 to 20 of 90

1.

Oxidized phospholipids stimulate angiogenesis via autocrine mechanisms, implicating a novel role for lipid oxidation in the evolution of atherosclerotic lesions.

Bochkov VN, Philippova M, Oskolkova O, Kadl A, Furnkranz A, Karabeg E, Afonyushkin T, Gruber F, Breuss J, Minchenko A, Mechtcheriakova D, Hohensinner P, Rychli K, Wojta J, Resink T, Erne P, Binder BR, Leitinger N.

Circ Res. 2006 Oct 13;99(8):900-8. Epub 2006 Sep 14.

2.

Permissive role of miR-663 in induction of VEGF and activation of the ATF4 branch of unfolded protein response in endothelial cells by oxidized phospholipids.

Afonyushkin T, Oskolkova OV, Bochkov VN.

Atherosclerosis. 2012 Nov;225(1):50-5. doi: 10.1016/j.atherosclerosis.2012.06.016. Epub 2012 Jun 23.

PMID:
22776647
3.

Polar head groups are important for barrier-protective effects of oxidized phospholipids on pulmonary endothelium.

Birukova AA, Fu P, Chatchavalvanich S, Burdette D, Oskolkova O, Bochkov VN, Birukov KG.

Am J Physiol Lung Cell Mol Physiol. 2007 Apr;292(4):L924-35. Epub 2006 Dec 8.

4.

ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response.

Oskolkova OV, Afonyushkin T, Leitner A, von Schlieffen E, Gargalovic PS, Lusis AJ, Binder BR, Bochkov VN.

Blood. 2008 Jul 15;112(2):330-9. doi: 10.1182/blood-2007-09-112870. Epub 2008 May 1.

5.

Oxidized phospholipids induce phenotypic switching of vascular smooth muscle cells in vivo and in vitro.

Pidkovka NA, Cherepanova OA, Yoshida T, Alexander MR, Deaton RA, Thomas JA, Leitinger N, Owens GK.

Circ Res. 2007 Oct 12;101(8):792-801. Epub 2007 Aug 17.

6.

Oxidized phospholipids trigger atherogenic inflammation in murine arteries.

Furnkranz A, Schober A, Bochkov VN, Bashtrykov P, Kronke G, Kadl A, Binder BR, Weber C, Leitinger N.

Arterioscler Thromb Vasc Biol. 2005 Mar;25(3):633-8. Epub 2004 Dec 9.

7.

Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo.

Gharavi NM, Alva JA, Mouillesseaux KP, Lai C, Yeh M, Yeung W, Johnson J, Szeto WL, Hong L, Fishbein M, Wei L, Pfeffer LM, Berliner JA.

J Biol Chem. 2007 Oct 26;282(43):31460-8. Epub 2007 Aug 28.

8.

Retinal pigment epithelium cells produce VEGF in response to oxidized phospholipids through mechanisms involving ATF4 and protein kinase CK2.

Pollreisz A, Afonyushkin T, Oskolkova OV, Gruber F, Bochkov VN, Schmidt-Erfurth U.

Exp Eye Res. 2013 Nov;116:177-84. doi: 10.1016/j.exer.2013.08.021. Epub 2013 Sep 7.

PMID:
24021586
9.

Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids.

Singleton PA, Chatchavalvanich S, Fu P, Xing J, Birukova AA, Fortune JA, Klibanov AM, Garcia JG, Birukov KG.

Circ Res. 2009 Apr 24;104(8):978-86. doi: 10.1161/CIRCRESAHA.108.193367. Epub 2009 Mar 12.

10.

A role for neutral sphingomyelinase activation in the inhibition of LPS action by phospholipid oxidation products.

Walton KA, Gugiu BG, Thomas M, Basseri RJ, Eliav DR, Salomon RG, Berliner JA.

J Lipid Res. 2006 Sep;47(9):1967-74. Epub 2006 Jun 14.

11.

Oxidized phospholipids stimulate tissue factor expression in human endothelial cells via activation of ERK/EGR-1 and Ca(++)/NFAT.

Bochkov VN, Mechtcheriakova D, Lucerna M, Huber J, Malli R, Graier WF, Hofer E, Binder BR, Leitinger N.

Blood. 2002 Jan 1;99(1):199-206.

12.

Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways.

Afonyushkin T, Oskolkova OV, Philippova M, Resink TJ, Erne P, Binder BR, Bochkov VN.

Arterioscler Thromb Vasc Biol. 2010 May;30(5):1007-13. doi: 10.1161/ATVBAHA.110.204354. Epub 2010 Feb 25.

13.

GRP78 is a novel receptor initiating a vascular barrier protective response to oxidized phospholipids.

Birukova AA, Singleton PA, Gawlak G, Tian X, Mirzapoiazova T, Mambetsariev B, Dubrovskyi O, Oskolkova OV, Bochkov VN, Birukov KG.

Mol Biol Cell. 2014 Jul 1;25(13):2006-16. doi: 10.1091/mbc.E13-12-0743. Epub 2014 May 14.

14.

Analysis of inflammatory gene induction by oxidized phospholipids in vivo by quantitative real-time RT-PCR in comparison with effects of LPS.

Kadl A, Huber J, Gruber F, Bochkov VN, Binder BR, Leitinger N.

Vascul Pharmacol. 2002 Apr;38(4):219-27.

PMID:
12449018
15.

Role of group II secretory phospholipase A2 in atherosclerosis: 2. Potential involvement of biologically active oxidized phospholipids.

Leitinger N, Watson AD, Hama SY, Ivandic B, Qiao JH, Huber J, Faull KF, Grass DS, Navab M, Fogelman AM, de Beer FC, Lusis AJ, Berliner JA.

Arterioscler Thromb Vasc Biol. 1999 May;19(5):1291-8.

16.

Metalloproteinase processing of HBEGF is a proximal event in the response of human aortic endothelial cells to oxidized phospholipids.

Lee S, Springstead JR, Parks BW, Romanoski CE, Palvolgyi R, Ho T, Nguyen P, Lusis AJ, Berliner JA.

Arterioscler Thromb Vasc Biol. 2012 May;32(5):1246-54. doi: 10.1161/ATVBAHA.111.241257. Epub 2012 Mar 8.

17.

Protein targets of oxidized phospholipids in endothelial cells.

Gugiu BG, Mouillesseaux K, Duong V, Herzog T, Hekimian A, Koroniak L, Vondriska TM, Watson AD.

J Lipid Res. 2008 Mar;49(3):510-20. Epub 2007 Dec 10.

18.

Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC.

Li R, Mouillesseaux KP, Montoya D, Cruz D, Gharavi N, Dun M, Koroniak L, Berliner JA.

Circ Res. 2006 Mar 17;98(5):642-50. Epub 2006 Feb 2.

19.

OKL38 is an oxidative stress response gene stimulated by oxidized phospholipids.

Li R, Chen W, Yanes R, Lee S, Berliner JA.

J Lipid Res. 2007 Mar;48(3):709-15. Epub 2006 Dec 27.

20.

Structurally similar oxidized phospholipids differentially regulate endothelial binding of monocytes and neutrophils.

Leitinger N, Tyner TR, Oslund L, Rizza C, Subbanagounder G, Lee H, Shih PT, Mackman N, Tigyi G, Territo MC, Berliner JA, Vora DK.

Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):12010-5.

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