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Items: 1 to 20 of 175

1.

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

Kirstetter P, Anderson K, Porse BT, Jacobsen SE, Nerlov C.

Nat Immunol. 2006 Oct;7(10):1048-56. Epub 2006 Sep 3.

PMID:
16951689
2.

Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation.

Scheller M, Huelsken J, Rosenbauer F, Taketo MM, Birchmeier W, Tenen DG, Leutz A.

Nat Immunol. 2006 Oct;7(10):1037-47. Epub 2006 Sep 3.

PMID:
16951686
3.

Activation of CCAAT/enhancer-binding protein alpha or PU.1 in hematopoietic stem cells leads to their reduced self-renewal and proliferation.

Fukuchi Y, Ito M, Shibata F, Kitamura T, Nakajima H.

Stem Cells. 2008 Dec;26(12):3172-81. doi: 10.1634/stemcells.2008-0320. Epub 2008 Sep 11.

4.

Canonical Wnt signaling promotes early hematopoietic progenitor formation and erythroid specification during embryonic stem cell differentiation.

Tarafdar A, Dobbin E, Corrigan P, Freeburn R, Wheadon H.

PLoS One. 2013 Nov 26;8(11):e81030. doi: 10.1371/journal.pone.0081030. eCollection 2013.

5.

Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity.

Trowbridge JJ, Guezguez B, Moon RT, Bhatia M.

Stem Cells. 2010 Aug;28(8):1379-89. doi: 10.1002/stem.457.

6.

Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion.

Perry JM, He XC, Sugimura R, Grindley JC, Haug JS, Ding S, Li L.

Genes Dev. 2011 Sep 15;25(18):1928-42. doi: 10.1101/gad.17421911. Epub 2011 Sep 2.

7.

Long-term, multilineage hematopoiesis occurs in the combined absence of beta-catenin and gamma-catenin.

Jeannet G, Scheller M, Scarpellino L, Duboux S, Gardiol N, Back J, Kuttler F, Malanchi I, Birchmeier W, Leutz A, Huelsken J, Held W.

Blood. 2008 Jan 1;111(1):142-9. Epub 2007 Sep 28.

8.

Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.

Oguro H, Yuan J, Ichikawa H, Ikawa T, Yamazaki S, Kawamoto H, Nakauchi H, Iwama A.

Cell Stem Cell. 2010 Mar 5;6(3):279-86. doi: 10.1016/j.stem.2010.01.005.

9.

Distinct functions of Sox2 control self-renewal and differentiation in the osteoblast lineage.

Seo E, Basu-Roy U, Zavadil J, Basilico C, Mansukhani A.

Mol Cell Biol. 2011 Nov;31(22):4593-608. doi: 10.1128/MCB.05798-11. Epub 2011 Sep 19.

10.

Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation.

Chiba T, Zheng YW, Kita K, Yokosuka O, Saisho H, Onodera M, Miyoshi H, Nakano M, Zen Y, Nakanuma Y, Nakauchi H, Iwama A, Taniguchi H.

Gastroenterology. 2007 Sep;133(3):937-50. Epub 2007 Jun 20.

PMID:
17673212
11.

Complementary and independent function for Hoxb4 and Bmi1 in HSC activity.

Faubert A, Chagraoui J, Mayotte N, Fr├ęchette M, Iscove NN, Humphries RK, Sauvageau G.

Cold Spring Harb Symp Quant Biol. 2008;73:555-64. doi: 10.1101/sqb.2008.73.030. Epub 2008 Nov 6.

PMID:
19022763
12.

Twist-1, a novel regulator of hematopoietic stem cell self-renewal and myeloid lineage development.

Dong CY, Liu XY, Wang N, Wang LN, Yang BX, Ren Q, Liang HY, Ma XT.

Stem Cells. 2014 Dec;32(12):3173-82. doi: 10.1002/stem.1803.

13.

MOZ is essential for maintenance of hematopoietic stem cells.

Katsumoto T, Aikawa Y, Iwama A, Ueda S, Ichikawa H, Ochiya T, Kitabayashi I.

Genes Dev. 2006 May 15;20(10):1321-30.

14.

Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus.

Hu Z, Negrotto S, Gu X, Mahfouz R, Ng KP, Ebrahem Q, Copelan E, Singh H, Maciejewski JP, Saunthararajah Y.

Mol Cancer Ther. 2010 Jun;9(6):1536-43. doi: 10.1158/1535-7163.MCT-10-0191. Epub 2010 May 25.

15.

Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation.

Luis TC, Weerkamp F, Naber BA, Baert MR, de Haas EF, Nikolic T, Heuvelmans S, De Krijger RR, van Dongen JJ, Staal FJ.

Blood. 2009 Jan 15;113(3):546-54. doi: 10.1182/blood-2008-06-163774. Epub 2008 Oct 2.

17.

Canonical Wnt pathway signaling suppresses VCAM-1 expression by marrow stromal and hematopoietic cells.

Malhotra S, Kincade PW.

Exp Hematol. 2009 Jan;37(1):19-30. doi: 10.1016/j.exphem.2008.08.008. Epub 2008 Oct 25.

18.

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML.

Jamieson CH, Ailles LE, Dylla SJ, Muijtjens M, Jones C, Zehnder JL, Gotlib J, Li K, Manz MG, Keating A, Sawyers CL, Weissman IL.

N Engl J Med. 2004 Aug 12;351(7):657-67.

19.

Sulfatase modifying factor 1-mediated fibroblast growth factor signaling primes hematopoietic multilineage development.

Buono M, Visigalli I, Bergamasco R, Biffi A, Cosma MP.

J Exp Med. 2010 Aug 2;207(8):1647-60. doi: 10.1084/jem.20091022. Epub 2010 Jul 19.

20.

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