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Items: 1 to 20 of 220

1.

Identification of the Syk kinase inhibitor R112 by a human mast cell screen.

Rossi AB, Herlaar E, Braselmann S, Huynh S, Taylor V, Frances R, Issakani SD, Argade A, Singh R, Payan DG, Masuda ES.

J Allergy Clin Immunol. 2006 Sep;118(3):749-55. Epub 2006 Jul 28.

PMID:
16950297
2.

Syk-kinase inhibition prevents mast cell activation in nasal polyps.

Patou J, Holtappels G, Affleck K, van Cauwenberge P, Bachert C.

Rhinology. 2011 Mar;49(1):100-6. doi: 10.4193/Rhino09.147.

PMID:
21468383
3.

Syk and Lyn mediate distinct Syk phosphorylation events in FcɛRI-signal transduction: implications for regulation of IgE-mediated degranulation.

Sanderson MP, Wex E, Kono T, Uto K, Schnapp A.

Mol Immunol. 2010 Nov-Dec;48(1-3):171-8. doi: 10.1016/j.molimm.2010.08.012. Epub 2010 Sep 15.

PMID:
20828828
4.

Camellia japonica suppresses immunoglobulin E-mediated allergic response by the inhibition of Syk kinase activation in mast cells.

Lee JH, Kim JW, Ko NY, Mun SH, Kim DK, Kim JD, Kim HS, Lee KR, Kim YK, Radinger M, Her E, Choi WS.

Clin Exp Allergy. 2008 May;38(5):794-804. doi: 10.1111/j.1365-2222.2008.02936.x. Epub 2008 Feb 2.

PMID:
18261158
5.

Syk inhibitors as treatment for allergic rhinitis.

Masuda ES, Schmitz J.

Pulm Pharmacol Ther. 2008;21(3):461-7. Epub 2007 Jun 28. Review.

PMID:
17669674
6.
7.

Characterization of syk expression in human lung mast cells: relationship with function.

Havard S, Scola AM, Kay LJ, Ishmael SS, MacGlashan DW Jr, Peachell PT.

Clin Exp Allergy. 2011 Mar;41(3):378-88. doi: 10.1111/j.1365-2222.2010.03667.x. Epub 2011 Jan 24.

PMID:
21255137
8.

Early divergence of Fc epsilon receptor I signals for receptor up-regulation and internalization from degranulation, cytokine production, and survival.

Kitaura J, Xiao W, Maeda-Yamamoto M, Kawakami Y, Lowell CA, Kawakami T.

J Immunol. 2004 Oct 1;173(7):4317-23.

9.

ER-27319, an acridone-related compound, inhibits release of antigen-induced allergic mediators from mast cells by selective inhibition of fcepsilon receptor I-mediated activation of Syk.

Moriya K, Rivera J, Odom S, Sakuma Y, Muramato K, Yoshiuchi T, Miyamoto M, Yamada K.

Proc Natl Acad Sci U S A. 1997 Nov 11;94(23):12539-44.

10.

Homoisoflavanone prevents mast cell activation and allergic responses by inhibition of Syk signaling pathway.

Lee YS, Hur S, Kim TY.

Allergy. 2014 Apr;69(4):453-62. doi: 10.1111/all.12356. Epub 2014 Jan 22.

11.

NecroX-5 suppresses IgE/Ag-stimulated anaphylaxis and mast cell activation by regulating the SHP-1-Syk signaling module.

Li X, Kwon O, Kim DY, Taketomi Y, Murakami M, Chang HW.

Allergy. 2016 Feb;71(2):198-209. doi: 10.1111/all.12786. Epub 2015 Nov 23.

PMID:
26456627
12.

Adenine suppresses IgE-mediated mast cell activation.

Silwal P, Shin K, Choi S, Kang SW, Park JB, Lee HJ, Koo SJ, Chung KH, Namgung U, Lim K, Heo JY, Park JI, Park SK.

Mol Immunol. 2015 Jun;65(2):242-9. doi: 10.1016/j.molimm.2015.01.021. Epub 2015 Feb 17.

PMID:
25700347
13.

Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction.

Moy LY, Jia Y, Caniga M, Lieber G, Gil M, Fernandez X, Sirkowski E, Miller R, Alexander JP, Lee HH, Shin JD, Ellis JM, Chen H, Wilhelm A, Yu H, Vincent S, Chapman RW, Kelly N, Hickey E, Abraham WM, Northrup A, Miller T, Houshyar H, Crackower MA.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):1085-92. doi: 10.1165/rcmb.2013-0200OC.

PMID:
23889698
14.

Antigen-induced reduction in mast cell and basophil functional responses due to reduced Syk protein levels.

Kepley CL.

Int Arch Allergy Immunol. 2005 Sep;138(1):29-39. Epub 2005 Aug 8.

PMID:
16088210
15.

Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness.

Matsubara S, Li G, Takeda K, Loader JE, Pine P, Masuda ES, Miyahara N, Miyahara S, Lucas JJ, Dakhama A, Gelfand EW.

Am J Respir Crit Care Med. 2006 Jan 1;173(1):56-63. Epub 2005 Sep 28.

16.

Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk.

Lee JH, Kim JW, Ko NY, Mun SH, Her E, Kim BK, Han JW, Lee HY, Beaven MA, Kim YM, Choi WS.

J Allergy Clin Immunol. 2008 May;121(5):1225-31. doi: 10.1016/j.jaci.2007.12.1160. Epub 2008 Apr 18.

PMID:
18394691
17.

Inhibition of spleen tyrosine kinase as treatment of postoperative ileus.

van Bree SH, Gomez-Pinilla PJ, van de Bovenkamp FS, Di Giovangiulio M, Farro G, Nemethova A, Cailotto C, de Jonge WJ, Lee K, Ramirez-Molina C, Lugo D, Skynner MJ, Boeckxstaens GE, Matteoli G.

Gut. 2013 Nov;62(11):1581-90. doi: 10.1136/gutjnl-2012-302615. Epub 2012 Dec 13.

PMID:
23242119
18.

Induced loss of Syk in human basophils by non-IgE-dependent stimuli.

MacGlashan DW Jr, Ishmael S, MacDonald SM, Langdon JM, Arm JP, Sloane DE.

J Immunol. 2008 Mar 15;180(6):4208-17.

20.

Human mast cell line-1 (HMC-1) cells transfected with FcεRIα are sensitive to IgE/antigen-mediated stimulation demonstrating selectivity towards cytokine production.

Xia YC, Sun S, Kuek LE, Lopata AL, Hulett MD, Mackay GA.

Int Immunopharmacol. 2011 Aug;11(8):1002-11. doi: 10.1016/j.intimp.2011.02.017. Epub 2011 Feb 26.

PMID:
21356342

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