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Items: 1 to 20 of 138

1.

Inhibitors of insulin-like growth factor signaling: a therapeutic approach for breast cancer.

Sachdev D, Yee D.

J Mammary Gland Biol Neoplasia. 2006 Jan;11(1):27-39. Review.

PMID:
16947084
2.

Targeting insulin-like growth factor in breast cancer therapeutics.

Karamouzis MV, Papavassiliou AG.

Crit Rev Oncol Hematol. 2012 Oct;84(1):8-17. doi: 10.1016/j.critrevonc.2012.02.010. Epub 2012 Mar 15. Review.

PMID:
22424863
3.

A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling in vitro and inhibits insulin-like growth factor-I receptor dependent tumor growth in vivo.

Ji QS, Mulvihill MJ, Rosenfeld-Franklin M, Cooke A, Feng L, Mak G, O'Connor M, Yao Y, Pirritt C, Buck E, Eyzaguirre A, Arnold LD, Gibson NW, Pachter JA.

Mol Cancer Ther. 2007 Aug;6(8):2158-67. Epub 2007 Aug 1.

4.

Targeting insulin-like growth factor type 1 receptor in cancer therapy.

Atzori F, Traina TA, Ionta MT, Massidda B.

Target Oncol. 2009 Dec;4(4):255-66. doi: 10.1007/s11523-009-0123-z. Epub 2009 Oct 30. Review.

PMID:
19876700
5.

Targeted therapy of the insulin-like growth factor-1 receptor in cancer.

Paz K, Hadari YR.

Comb Chem High Throughput Screen. 2008 Jan;11(1):62-9. Review.

PMID:
18220543
6.

Insulin-Like Growth Factor (IGF) family and prostate cancer.

Gennigens C, Menetrier-Caux C, Droz JP.

Crit Rev Oncol Hematol. 2006 May;58(2):124-45. Epub 2006 Jan 18. Review.

PMID:
16387509
7.

The insulin-like growth factor 1 receptor in cancer: old focus, new future.

Hartog H, Wesseling J, Boezen HM, van der Graaf WT.

Eur J Cancer. 2007 Sep;43(13):1895-904. Epub 2007 Jul 10. Review.

PMID:
17624760
8.

Medicinal chemistry approaches to target the kinase activity of IGF-1R.

Garcia-Echeverria C.

IDrugs. 2006 Jun;9(6):415-9.

PMID:
16752311
9.

Molecular predictors of response to a humanized anti-insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer.

Zha J, O'Brien C, Savage H, Huw LY, Zhong F, Berry L, Lewis Phillips GD, Luis E, Cavet G, Hu X, Amler LC, Lackner MR.

Mol Cancer Ther. 2009 Aug;8(8):2110-21. doi: 10.1158/1535-7163.MCT-09-0381. Epub 2009 Aug 11.

10.

The therapeutic potential of agents targeting the type I insulin-like growth factor receptor.

Zhang H, Yee D.

Expert Opin Investig Drugs. 2004 Dec;13(12):1569-77. Review.

PMID:
15566314
11.

IGF-IR: potential role in antitumor agents.

Guerreiro AS, Boller D, Doepfner KT, Arcaro A.

Drug News Perspect. 2006 Jun;19(5):261-72. Review.

PMID:
16941048
12.

The insulin-like growth factor system in advanced breast cancer.

Helle SI.

Best Pract Res Clin Endocrinol Metab. 2004 Mar;18(1):67-79. Review.

PMID:
14687598
13.

Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I).

Jernberg-Wiklund H, Nilsson K.

Adv Cancer Res. 2007;97:139-65. Review.

PMID:
17419944
14.

Insulin-like growth factor 1 receptor targeted therapeutics: novel compounds and novel treatment strategies for cancer medicine.

Hewish M, Chau I, Cunningham D.

Recent Pat Anticancer Drug Discov. 2009 Jan;4(1):54-72. Review.

PMID:
19149688
15.

Potential therapeutic strategies to interrupt insulin-like growth factor signaling in breast cancer.

Byron SA, Yee D.

Semin Oncol. 2003 Oct;30(5 Suppl 16):125-32. Review.

PMID:
14613033
16.

Insulin-like growth factor-1 receptor (IGF-1R) kinase inhibitors in cancer therapy: advances and perspectives.

Xue M, Cao X, Zhong Y, Kuang D, Liu X, Zhao Z, Li H.

Curr Pharm Des. 2012;18(20):2901-13. Review.

PMID:
22571659
17.

The insulin like growth factor-1 receptor (IGF-1R) as a drug target: novel approaches to cancer therapy.

Bähr C, Groner B.

Growth Horm IGF Res. 2004 Aug;14(4):287-95. Review.

PMID:
15231297
18.

Crosstalk between epidermal growth factor receptor- and insulin-like growth factor-1 receptor signaling: implications for cancer therapy.

van der Veeken J, Oliveira S, Schiffelers RM, Storm G, van Bergen En Henegouwen PM, Roovers RC.

Curr Cancer Drug Targets. 2009 Sep;9(6):748-60. Review.

PMID:
19754359
19.

Anti-insulin-like growth factor strategies in breast cancer.

Jerome L, Shiry L, Leyland-Jones B.

Semin Oncol. 2004 Feb;31(1 Suppl 3):54-63. Review.

PMID:
15052543
20.

ATP non-competitive IGF-1 receptor kinase inhibitors as lead anti-neoplastic and anti-papilloma agents.

Steiner L, Blum G, Friedmann Y, Levitzki A.

Eur J Pharmacol. 2007 May 7;562(1-2):1-11. Epub 2007 Feb 3.

PMID:
17376430

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