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Items: 1 to 20 of 74

1.

Itk and Th2 responses: action but no reaction.

Kosaka Y, Felices M, Berg LJ.

Trends Immunol. 2006 Oct;27(10):453-60. Review.

PMID:
16931156
2.

Mutation of Tec family kinases alters T helper cell differentiation.

Schaeffer EM, Yap GS, Lewis CM, Czar MJ, McVicar DW, Cheever AW, Sher A, Schwartzberg PL.

Nat Immunol. 2001 Dec;2(12):1183-8.

PMID:
11702066
3.

Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses.

Sahu N, Venegas AM, Jankovic D, Mitzner W, Gomez-Rodriguez J, Cannons JL, Sommers C, Love P, Sher A, Schwartzberg PL, August A.

J Immunol. 2008 Nov 1;181(9):6125-31.

4.

Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet.

Miller AT, Wilcox HM, Lai Z, Berg LJ.

Immunity. 2004 Jul;21(1):67-80.

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Differential sensitivity to Itk kinase signals for T helper 2 cytokine production and chemokine-mediated migration.

Sahu N, Mueller C, Fischer A, August A.

J Immunol. 2008 Mar 15;180(6):3833-8. Erratum in: J Immunol. 2008 May 15;180(10):7047-8.

7.

Subtle defects in pre-TCR signaling in the absence of the Tec kinase Itk.

Lucas JA, Felices M, Evans JW, Berg LJ.

J Immunol. 2007 Dec 1;179(11):7561-7.

8.

Tec kinases Itk and Rlk are required for CD8+ T cell responses to virus infection independent of their role in CD4+ T cell help.

Atherly LO, Brehm MA, Welsh RM, Berg LJ.

J Immunol. 2006 Feb 1;176(3):1571-81. Erratum in: J Immunol. 2006 Mar 15;176(6):3842.

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10.

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells.

Fowell DJ, Shinkai K, Liao XC, Beebe AM, Coffman RL, Littman DR, Locksley RM.

Immunity. 1999 Oct;11(4):399-409.

11.
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13.

A key role for Itk in both IFN gamma and IL-4 production by NKT cells.

Au-Yeung BB, Fowell DJ.

J Immunol. 2007 Jul 1;179(1):111-9.

14.
15.

Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton.

Dombroski D, Houghtling RA, Labno CM, Precht P, Takesono A, Caplen NJ, Billadeau DD, Wange RL, Burkhardt JK, Schwartzberg PL.

J Immunol. 2005 Feb 1;174(3):1385-92.

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17.

TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development.

Sun J, Walsh M, Villarino AV, Cervi L, Hunter CA, Choi Y, Pearce EJ.

J Immunol. 2005 Jan 15;174(2):742-51.

18.

The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells.

Atherly LO, Lucas JA, Felices M, Yin CC, Reiner SL, Berg LJ.

Immunity. 2006 Jul;25(1):79-91.

19.

TEC-family kinases: regulators of T-helper-cell differentiation.

Schwartzberg PL, Finkelstein LD, Readinger JA.

Nat Rev Immunol. 2005 Apr;5(4):284-95. Review.

PMID:
15803148
20.

Allele-sensitive mutant, Itkas, reveals that Itk kinase activity is required for Th1, Th2, Th17, and iNKT-cell cytokine production.

Kannan A, Lee Y, Qi Q, Huang W, Jeong AR, Ohnigian S, August A.

Eur J Immunol. 2015 Aug;45(8):2276-85. doi: 10.1002/eji.201445087.

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