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Items: 1 to 20 of 208

1.

Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design.

Tsao DH, Sutherland AG, Jennings LD, Li Y, Rush TS 3rd, Alvarez JC, Ding W, Dushin EG, Dushin RG, Haney SA, Kenny CH, Malakian AK, Nilakantan R, Mosyak L.

Bioorg Med Chem. 2006 Dec 1;14(23):7953-61. Epub 2006 Aug 17.

PMID:
16919463
2.

Development of a fluorescence polarization assay to screen for inhibitors of the FtsZ/ZipA interaction.

Kenny CH, Ding W, Kelleher K, Benard S, Dushin EG, Sutherland AG, Mosyak L, Kriz R, Ellestad G.

Anal Biochem. 2003 Dec 15;323(2):224-33.

PMID:
14656529
3.

Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction.

Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Li Y, Sukhdeo MN, Ding W, Dushin EG, Kenny CH, Moghazeh SL, Petersen PJ, Ruzin AV, Tuckman M, Sutherland AG.

Bioorg Med Chem Lett. 2004 Mar 22;14(6):1427-31.

PMID:
15006376
4.

Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA-FtsZ interaction.

Jennings LD, Foreman KW, Rush TS 3rd, Tsao DH, Mosyak L, Kincaid SL, Sukhdeo MN, Sutherland AG, Ding W, Kenny CH, Sabus CL, Liu H, Dushin EG, Moghazeh SL, Labthavikul P, Petersen PJ, Tuckman M, Haney SA, Ruzin AV.

Bioorg Med Chem. 2004 Oct 1;12(19):5115-31. Erratum in: Bioorg Med Chem. 2005 Oct 15;13(20):5884. Haney, Steven A [added].

PMID:
15351395
5.

Structure-based design of carboxybiphenylindole inhibitors of the ZipA-FtsZ interaction.

Sutherland AG, Alvarez J, Ding W, Foreman KW, Kenny CH, Labthavikul P, Mosyak L, Petersen PJ, Rush TS 3rd, Ruzin A, Tsao DH, Wheless KL.

Org Biomol Chem. 2003 Dec 7;1(23):4138-40. Epub 2003 Oct 29.

PMID:
14685315
6.

Solution structure of ZipA, a crucial component of Escherichia coli cell division.

Moy FJ, Glasfeld E, Mosyak L, Powers R.

Biochemistry. 2000 Aug 8;39(31):9146-56.

PMID:
10924108
7.

A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction.

Rush TS 3rd, Grant JA, Mosyak L, Nicholls A.

J Med Chem. 2005 Mar 10;48(5):1489-95.

PMID:
15743191
8.

The bacterial cell-division protein ZipA and its interaction with an FtsZ fragment revealed by X-ray crystallography.

Mosyak L, Zhang Y, Glasfeld E, Haney S, Stahl M, Seehra J, Somers WS.

EMBO J. 2000 Jul 3;19(13):3179-91.

9.

Recruitment of ZipA to the division site by interaction with FtsZ.

Liu Z, Mukherjee A, Lutkenhaus J.

Mol Microbiol. 1999 Mar;31(6):1853-61.

10.

Detailed microscopic study of the full zipA:FtsZ interface.

Moreira IS, Fernandes PA, Ramos MJ.

Proteins. 2006 Jun 1;63(4):811-21.

PMID:
16538616
11.

A specific role for the ZipA protein in cell division: stabilization of the FtsZ protein.

Pazos M, Natale P, Vicente M.

J Biol Chem. 2013 Feb 1;288(5):3219-26. doi: 10.1074/jbc.M112.434944. Epub 2012 Dec 11.

12.
13.

Dynamic interaction of the Escherichia coli cell division ZipA and FtsZ proteins evidenced in nanodiscs.

Hernández-Rocamora VM, Reija B, García C, Natale P, Alfonso C, Minton AP, Zorrilla S, Rivas G, Vicente M.

J Biol Chem. 2012 Aug 31;287(36):30097-104. doi: 10.1074/jbc.M112.388959. Epub 2012 Jul 11.

14.

The FtsZ protofilament and attachment of ZipA--structural constraints on the FtsZ power stroke.

Erickson HP.

Curr Opin Cell Biol. 2001 Feb;13(1):55-60. Review.

PMID:
11163134
15.
16.

The Escherichia coli cell division protein ZipA forms homodimers prior to association with FtsZ.

Skoog K, Daley DO.

Biochemistry. 2012 Feb 21;51(7):1407-15. doi: 10.1021/bi2015647. Epub 2012 Feb 9.

PMID:
22304478
17.
18.

Structure-guided fragment screening for lead discovery.

Verdonk ML, Hartshorn MJ.

Curr Opin Drug Discov Devel. 2004 Jul;7(4):404-10. Review.

PMID:
15338949
19.

Reconstitution of the Escherichia coli cell division ZipA-FtsZ complexes in nanodiscs as revealed by electron microscopy.

Hernández-Rocamora VM, García-Montañés C, Rivas G, Llorca O.

J Struct Biol. 2012 Dec;180(3):531-8. doi: 10.1016/j.jsb.2012.08.013. Epub 2012 Sep 19.

PMID:
23000704
20.

ZipA binds to FtsZ with high affinity and enhances the stability of FtsZ protofilaments.

Kuchibhatla A, Bhattacharya A, Panda D.

PLoS One. 2011;6(12):e28262. doi: 10.1371/journal.pone.0028262. Epub 2011 Dec 2.

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