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Seminal plasma promotes the expression of tumorigenic and angiogenic genes in cervical adenocarcinoma cells via the E-series prostanoid 4 receptor.

Muller M, Sales KJ, Katz AA, Jabbour HN.

Endocrinology. 2006 Jul;147(7):3356-65. Epub 2006 Mar 30.


The prostaglandin receptor EP2 activates multiple signaling pathways and beta-arrestin1 complex formation during mouse skin papilloma development.

Chun KS, Lao HC, Trempus CS, Okada M, Langenbach R.

Carcinogenesis. 2009 Sep;30(9):1620-7. doi: 10.1093/carcin/bgp168. Epub 2009 Jul 8.


F-prostanoid receptor regulation of fibroblast growth factor 2 signaling in endometrial adenocarcinoma cells.

Sales KJ, Boddy SC, Williams AR, Anderson RA, Jabbour HN.

Endocrinology. 2007 Aug;148(8):3635-44. Epub 2007 May 3.


Prostaglandin E2 and F2alpha activate the FP receptor and up-regulate cyclooxygenase-2 expression via the cyclic AMP response element.

Sales KJ, Grant V, Jabbour HN.

Mol Cell Endocrinol. 2008 Mar 26;285(1-2):51-61. doi: 10.1016/j.mce.2008.01.016. Epub 2008 Feb 3.


EP2 prostanoid receptor promotes squamous cell carcinoma growth through epidermal growth factor receptor transactivation and iNOS and ERK1/2 pathways.

Donnini S, Finetti F, Solito R, Terzuoli E, Sacchetti A, Morbidelli L, Patrignani P, Ziche M.

FASEB J. 2007 Aug;21(10):2418-30. Epub 2007 Mar 23.


Hypoxia and prostaglandin E receptor 4 signalling pathways synergise to promote endometrial adenocarcinoma cell proliferation and tumour growth.

Catalano RD, Wilson MR, Boddy SC, McKinlay AT, Sales KJ, Jabbour HN.

PLoS One. 2011 May 12;6(5):e19209. doi: 10.1371/journal.pone.0019209.


A novel angiogenic role for prostaglandin F2alpha-FP receptor interaction in human endometrial adenocarcinomas.

Sales KJ, List T, Boddy SC, Williams AR, Anderson RA, Naor Z, Jabbour HN.

Cancer Res. 2005 Sep 1;65(17):7707-16.


Role of the prostaglandin E2/E-prostanoid 2 receptor signalling pathway in TGFβ-induced mice mesangial cell damage.

Li NN, Xu YY, Chen XL, Fan YP, Wu JH.

Biosci Rep. 2014 Dec 12;34(6):e00159. doi: 10.1042/BSR20140130.


Phosphatase and tensin homologue on chromosome 10 (PTEN) directs prostaglandin E2-mediated fibroblast responses via regulation of E prostanoid 2 receptor expression.

Sagana RL, Yan M, Cornett AM, Tsui JL, Stephenson DA, Huang SK, Moore BB, Ballinger MN, Melonakos J, Kontos CD, Aronoff DM, Peters-Golden M, White ES.

J Biol Chem. 2009 Nov 20;284(47):32264-71. doi: 10.1074/jbc.M109.004796. Epub 2009 Oct 6.


The soluble EP2 receptor FuEP2/Ex2 suppresses endometrial cancer cell growth in an orthotopic xenograft model in nude mice.

Takahashi T, Ogawa H, Izumi K, Uehara H.

Cancer Lett. 2011 Jul 1;306(1):67-75. doi: 10.1016/j.canlet.2011.02.033. Epub 2011 Mar 17.


Prostaglandin E2 promotes wound-induced migration of intestinal subepithelial myofibroblasts via EP2, EP3, and EP4 prostanoid receptor activation.

Iwanaga K, Okada M, Murata T, Hori M, Ozaki H.

J Pharmacol Exp Ther. 2012 Mar;340(3):604-11. doi: 10.1124/jpet.111.189845. Epub 2011 Dec 2.

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